Monitoring sepsis using electrical cell profiling in a mouse model

Hao Wei Su, Javier L. Prieto, Lidan Wu, Han Wei Hou, Miguel Pinilla Vera, Diana Amador-Munoz, Joshua L. Englert, Bruce D. Levy, Rebecca M. Baron, Jongyoon Han, Joel Voldman

Research output: Chapter in Book/ReportConference contribution

1 Scopus citations

Abstract

We developed double-sided iso-dielectric separation system for monitoring sepsis progression using electrical characterization of leukocyte activation. With inertial sorter integration, we can characterize the electrical properties of leukocytes from ∼ 50 μL sample of whole blood within 15 minute. In the end, we quantify leukocyte activation in a mouse sepsis model, representing the first use of electrical cell profiling to provide a clinically relevant metric.

Original languageEnglish (US)
Title of host publication18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014
PublisherChemical and Biological Microsystems Society
Pages327-329
Number of pages3
ISBN (Electronic)9780979806476
StatePublished - 2014
Externally publishedYes
Event18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014 - San Antonio, United States
Duration: Oct 26 2014Oct 30 2014

Publication series

Name18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014

Conference

Conference18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014
Country/TerritoryUnited States
CitySan Antonio
Period10/26/1410/30/14

All Science Journal Classification (ASJC) codes

  • Control and Systems Engineering

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