Interindividual responses to different exercise stimuli among insulin-resistant women

C. Álvarez, R. Ramírez-Vélez, R. Ramírez-Campillo, S. Ito, C. Celis-Morales, A. García-Hermoso, L. Rodriguez-Mañas, A. Lucia, M. Izquierdo

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

We aimed to investigate which among 20 cardiometabolic and performance outcomes do and do not respond to high-intensity interval training (HIT), resistance training (RT), or concurrent training (CT) in insulin-resistant adult women. A secondary aim was to report the training-induced changes and the prevalence of non-responders. Forty-five insulin-resistant adult women were randomly assigned to one of the following 4 groups: HIT (39.2 ± 9.5 years [y]; body mass index [BMI], 29.3 ± 3.3; n = 14), RT (33.9 ± 9.3 y; BMI, 29.4 ± 5.5; n = 8), CT (43.3 ± 8.1 y; BMI, 29.1 ± 2.9; n = 10), and a control group (CG, 40.1 ± 11.4 y; BMI, 28.3 ± 3.5; n = 13). Nine body composition, 3 cardiovascular, 3 metabolic, and 5 performance outcomes were assessed at baseline and after 12 weeks of intervention. Considering all outcomes, the lowest number of total non-responses for one or more variables was found in the RT group, followed by the CT and HIT groups. Individuals in the CG group were classified as non-responders for almost all the variables. Moreover, there were several significant changes in body composition and metabolic parameters, including fasting glucose (HIT: −5.7, RT −5.1 mg/d), fasting insulin (HIT: −0.6, RT −0.6 μIU/mL), and HOMA-IR (HIT: −0.3, RT −0.4), in addition to improvements in cardiovascular and performance parameters. Also, there were significant differences among groups in the prevalence of non-responders for the variables where a non-response was detected. Overall, the study suggests that independent of the mode of training including volume and frequency, RT has an important ability to reduce the prevalence of non-response to improve the 20 outcomes of health and performance in insulin-resistant adult women.

Original languageEnglish (US)
Pages (from-to)2052-2065
Number of pages14
JournalScandinavian Journal of Medicine and Science in Sports
Volume28
Issue number9
DOIs
StatePublished - May 11 2018

All Science Journal Classification (ASJC) codes

  • Orthopedics and Sports Medicine
  • Physical Therapy, Sports Therapy and Rehabilitation

Cite this

Álvarez, C., Ramírez-Vélez, R., Ramírez-Campillo, R., Ito, S., Celis-Morales, C., García-Hermoso, A., ... Izquierdo, M. (2018). Interindividual responses to different exercise stimuli among insulin-resistant women. Scandinavian Journal of Medicine and Science in Sports, 28(9), 2052-2065. https://doi.org/10.1111/sms.13213
Álvarez, C. ; Ramírez-Vélez, R. ; Ramírez-Campillo, R. ; Ito, S. ; Celis-Morales, C. ; García-Hermoso, A. ; Rodriguez-Mañas, L. ; Lucia, A. ; Izquierdo, M. / Interindividual responses to different exercise stimuli among insulin-resistant women. In: Scandinavian Journal of Medicine and Science in Sports. 2018 ; Vol. 28, No. 9. pp. 2052-2065.
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abstract = "We aimed to investigate which among 20 cardiometabolic and performance outcomes do and do not respond to high-intensity interval training (HIT), resistance training (RT), or concurrent training (CT) in insulin-resistant adult women. A secondary aim was to report the training-induced changes and the prevalence of non-responders. Forty-five insulin-resistant adult women were randomly assigned to one of the following 4 groups: HIT (39.2 ± 9.5 years [y]; body mass index [BMI], 29.3 ± 3.3; n = 14), RT (33.9 ± 9.3 y; BMI, 29.4 ± 5.5; n = 8), CT (43.3 ± 8.1 y; BMI, 29.1 ± 2.9; n = 10), and a control group (CG, 40.1 ± 11.4 y; BMI, 28.3 ± 3.5; n = 13). Nine body composition, 3 cardiovascular, 3 metabolic, and 5 performance outcomes were assessed at baseline and after 12 weeks of intervention. Considering all outcomes, the lowest number of total non-responses for one or more variables was found in the RT group, followed by the CT and HIT groups. Individuals in the CG group were classified as non-responders for almost all the variables. Moreover, there were several significant changes in body composition and metabolic parameters, including fasting glucose (HIT: −5.7, RT −5.1 mg/d), fasting insulin (HIT: −0.6, RT −0.6 μIU/mL), and HOMA-IR (HIT: −0.3, RT −0.4), in addition to improvements in cardiovascular and performance parameters. Also, there were significant differences among groups in the prevalence of non-responders for the variables where a non-response was detected. Overall, the study suggests that independent of the mode of training including volume and frequency, RT has an important ability to reduce the prevalence of non-response to improve the 20 outcomes of health and performance in insulin-resistant adult women.",
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Álvarez, C, Ramírez-Vélez, R, Ramírez-Campillo, R, Ito, S, Celis-Morales, C, García-Hermoso, A, Rodriguez-Mañas, L, Lucia, A & Izquierdo, M 2018, 'Interindividual responses to different exercise stimuli among insulin-resistant women', Scandinavian Journal of Medicine and Science in Sports, vol. 28, no. 9, pp. 2052-2065. https://doi.org/10.1111/sms.13213

Interindividual responses to different exercise stimuli among insulin-resistant women. / Álvarez, C.; Ramírez-Vélez, R.; Ramírez-Campillo, R.; Ito, S.; Celis-Morales, C.; García-Hermoso, A.; Rodriguez-Mañas, L.; Lucia, A.; Izquierdo, M.

In: Scandinavian Journal of Medicine and Science in Sports, Vol. 28, No. 9, 11.05.2018, p. 2052-2065.

Research output: Contribution to journalArticle

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AU - Álvarez, C.

AU - Ramírez-Vélez, R.

AU - Ramírez-Campillo, R.

AU - Ito, S.

AU - Celis-Morales, C.

AU - García-Hermoso, A.

AU - Rodriguez-Mañas, L.

AU - Lucia, A.

AU - Izquierdo, M.

PY - 2018/5/11

Y1 - 2018/5/11

N2 - We aimed to investigate which among 20 cardiometabolic and performance outcomes do and do not respond to high-intensity interval training (HIT), resistance training (RT), or concurrent training (CT) in insulin-resistant adult women. A secondary aim was to report the training-induced changes and the prevalence of non-responders. Forty-five insulin-resistant adult women were randomly assigned to one of the following 4 groups: HIT (39.2 ± 9.5 years [y]; body mass index [BMI], 29.3 ± 3.3; n = 14), RT (33.9 ± 9.3 y; BMI, 29.4 ± 5.5; n = 8), CT (43.3 ± 8.1 y; BMI, 29.1 ± 2.9; n = 10), and a control group (CG, 40.1 ± 11.4 y; BMI, 28.3 ± 3.5; n = 13). Nine body composition, 3 cardiovascular, 3 metabolic, and 5 performance outcomes were assessed at baseline and after 12 weeks of intervention. Considering all outcomes, the lowest number of total non-responses for one or more variables was found in the RT group, followed by the CT and HIT groups. Individuals in the CG group were classified as non-responders for almost all the variables. Moreover, there were several significant changes in body composition and metabolic parameters, including fasting glucose (HIT: −5.7, RT −5.1 mg/d), fasting insulin (HIT: −0.6, RT −0.6 μIU/mL), and HOMA-IR (HIT: −0.3, RT −0.4), in addition to improvements in cardiovascular and performance parameters. Also, there were significant differences among groups in the prevalence of non-responders for the variables where a non-response was detected. Overall, the study suggests that independent of the mode of training including volume and frequency, RT has an important ability to reduce the prevalence of non-response to improve the 20 outcomes of health and performance in insulin-resistant adult women.

AB - We aimed to investigate which among 20 cardiometabolic and performance outcomes do and do not respond to high-intensity interval training (HIT), resistance training (RT), or concurrent training (CT) in insulin-resistant adult women. A secondary aim was to report the training-induced changes and the prevalence of non-responders. Forty-five insulin-resistant adult women were randomly assigned to one of the following 4 groups: HIT (39.2 ± 9.5 years [y]; body mass index [BMI], 29.3 ± 3.3; n = 14), RT (33.9 ± 9.3 y; BMI, 29.4 ± 5.5; n = 8), CT (43.3 ± 8.1 y; BMI, 29.1 ± 2.9; n = 10), and a control group (CG, 40.1 ± 11.4 y; BMI, 28.3 ± 3.5; n = 13). Nine body composition, 3 cardiovascular, 3 metabolic, and 5 performance outcomes were assessed at baseline and after 12 weeks of intervention. Considering all outcomes, the lowest number of total non-responses for one or more variables was found in the RT group, followed by the CT and HIT groups. Individuals in the CG group were classified as non-responders for almost all the variables. Moreover, there were several significant changes in body composition and metabolic parameters, including fasting glucose (HIT: −5.7, RT −5.1 mg/d), fasting insulin (HIT: −0.6, RT −0.6 μIU/mL), and HOMA-IR (HIT: −0.3, RT −0.4), in addition to improvements in cardiovascular and performance parameters. Also, there were significant differences among groups in the prevalence of non-responders for the variables where a non-response was detected. Overall, the study suggests that independent of the mode of training including volume and frequency, RT has an important ability to reduce the prevalence of non-response to improve the 20 outcomes of health and performance in insulin-resistant adult women.

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Álvarez C, Ramírez-Vélez R, Ramírez-Campillo R, Ito S, Celis-Morales C, García-Hermoso A et al. Interindividual responses to different exercise stimuli among insulin-resistant women. Scandinavian Journal of Medicine and Science in Sports. 2018 May 11;28(9):2052-2065. https://doi.org/10.1111/sms.13213