Evaluation of OIDx Histoplasma urinary antigen EIA

Diego H Cáceres, Beatriz L. Gómez, Ángela M Tobón, Tom M Chiller, Mark D Lindsley

Research output: Contribution to journalArticlepeer-review

Abstract

A sandwich enzyme immunoassay (EIA) for the detection of Histoplasma antigens (Ag) in urine, developed by Optimum Imaging Diagnostics (OIDx) was evaluated. A verification using a standardized reference panel of urine samples found sensitivity of 92%, specificity of 32% and accuracy of 51%. In this study, the OIDx Histoplasma urinary Ag EIA displayed high sensitivity, however, in non-histoplasmosis cases this EIA displayed false-positive results in 68% of specimens tested.

Original languageEnglish (US)
Pages (from-to)129–131
JournalMycopathologia
Volume187
DOIs
StatePublished - Nov 20 2021

All Science Journal Classification (ASJC) codes

  • Medicine(all)

Author Keywords

  • Concept

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