Evaluation of OIDx Histoplasma urinary antigen EIA

Diego H Cáceres; Beatriz L. Gómez; Ángela M Tobón; Tom M Chiller; Mark D Lindsley

doi:10.1007/s11046-021-00602-9

Evaluation of OIDx Histoplasma urinary antigen EIA

Diego H Cáceres, Beatriz L. Gómez, Ángela M Tobón, Tom M Chiller, Mark D Lindsley

Producción científica: Contribución a una revista › Artículo › revisión exhaustiva

6 Citas (Scopus)

Resumen

A sandwich enzyme immunoassay (EIA) for the detection of Histoplasma antigens (Ag) in urine, developed by Optimum Imaging Diagnostics (OIDx) was evaluated. A verification using a standardized reference panel of urine samples found sensitivity of 92%, specificity of 32% and accuracy of 51%. In this study, the OIDx Histoplasma urinary Ag EIA displayed high sensitivity, however, in non-histoplasmosis cases this EIA displayed false-positive results in 68% of specimens tested.

Idioma original	Inglés estadounidense
Páginas (desde-hasta)	129–131
Publicación	Mycopathologia
Volumen	187
DOI	https://doi.org/10.1007/s11046-021-00602-9
Estado	Publicada - nov. 20 2021

Áreas temáticas de ASJC Scopus

Medicina General

Acceder al documento

10.1007/s11046-021-00602-9

Citar esto

@article{401b944933894ce58f015a94fd59b3d3,

title = "Evaluation of OIDx Histoplasma urinary antigen EIA",

abstract = "A sandwich enzyme immunoassay (EIA) for the detection of Histoplasma antigens (Ag) in urine, developed by Optimum Imaging Diagnostics (OIDx) was evaluated. A verification using a standardized reference panel of urine samples found sensitivity of 92%, specificity of 32% and accuracy of 51%. In this study, the OIDx Histoplasma urinary Ag EIA displayed high sensitivity, however, in non-histoplasmosis cases this EIA displayed false-positive results in 68% of specimens tested.",

author = "C{\'a}ceres, {Diego H} and G{\'o}mez, {Beatriz L.} and Tob{\'o}n, {{\'A}ngela M} and Chiller, {Tom M} and Lindsley, {Mark D}",

note = "{\textcopyright} 2021. This is a U.S. government work and not under copyright protection in the U.S.; foreign copyright protection may apply.",

year = "2021",

month = nov,

day = "20",

doi = "10.1007/s11046-021-00602-9",

language = "English (US)",

volume = "187",

pages = "129–131 ",

journal = "Mycopathologia",

issn = "0301-486X",

publisher = "Springer Netherlands",

}

TY - JOUR

T1 - Evaluation of OIDx Histoplasma urinary antigen EIA

AU - Cáceres, Diego H

AU - Gómez, Beatriz L.

AU - Tobón, Ángela M

AU - Chiller, Tom M

AU - Lindsley, Mark D

PY - 2021/11/20

Y1 - 2021/11/20

N2 - A sandwich enzyme immunoassay (EIA) for the detection of Histoplasma antigens (Ag) in urine, developed by Optimum Imaging Diagnostics (OIDx) was evaluated. A verification using a standardized reference panel of urine samples found sensitivity of 92%, specificity of 32% and accuracy of 51%. In this study, the OIDx Histoplasma urinary Ag EIA displayed high sensitivity, however, in non-histoplasmosis cases this EIA displayed false-positive results in 68% of specimens tested.

AB - A sandwich enzyme immunoassay (EIA) for the detection of Histoplasma antigens (Ag) in urine, developed by Optimum Imaging Diagnostics (OIDx) was evaluated. A verification using a standardized reference panel of urine samples found sensitivity of 92%, specificity of 32% and accuracy of 51%. In this study, the OIDx Histoplasma urinary Ag EIA displayed high sensitivity, however, in non-histoplasmosis cases this EIA displayed false-positive results in 68% of specimens tested.

U2 - 10.1007/s11046-021-00602-9

DO - 10.1007/s11046-021-00602-9

M3 - Article

C2 - 34802111

SN - 0301-486X

VL - 187

SP - 129

EP - 131

JO - Mycopathologia

JF - Mycopathologia

ER -

Evaluation of OIDx Histoplasma urinary antigen EIA

Resumen

Áreas temáticas de ASJC Scopus

Acceder al documento

Huella

Citar esto