Genetic factors associated with clinical severity in the Colombian population affected by SARS-CoV-2.

Project: Research Project

Project Details


Introduction: The variability in host genetic factors against SARS-CoV-2 infection has not been explored in our population.

These factors are considered critical in the clinical evolution of COVID-19.

Objective: The present project seeks to evaluate the association of polymorphisms in susceptibility genes and ancestral markers with the severity of COVID-19 and the presence of sequelae in the Colombian population.

Methodology: To do this, using next generation sequencing (NGS), genotyping of patients with different degrees of severity of COVID-19 will be carried out.

The genetic and non-genetic information obtained will allow the construction of a risk assessment model.

Expected results: The study will allow us to analyze the association of the polymorphisms evaluated with SARS-CoV-2 infection in the Colombian population, contributing to the understanding of the role of host genetics in the course of the disease.

Likewise, these results will allow the construction of a predictive model of potential clinical utility.

This research is carried out in collaboration with the Mayor-Méderi University Hospital.


SARS-CoV-2, genomic medicine, genetic susceptibility, “long-COVID”, predictive model.
Effective start/end date2/1/228/31/23

UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This project contributes towards the following SDG(s):

  • SDG 3 - Good Health and Well-being

Main Funding Source

  • National


  • Bogotá D.C.


Explore the research topics touched on by this project. These labels are generated based on the underlying awards/grants. Together they form a unique fingerprint.