Rheumatoid pericarditis: New immunopathological aspects

A. Travaglio-Encinoza, J. M. Anaya, A. D. D'Angeac, T. Reme, J. Sany

Resultado de la investigación: Contribución a una revistaArtículorevisión exhaustiva

7 Citas (Scopus)

Resumen

Rheumatoid pericarditis (RP) is a well known extraarticular manifestation of rheumatoid arthritis (RA). It is not frequently diagnosed despite its high reported prevalence in post-mortem studies. There have been no immunohistological studies of its presence in pericardial membranes. Here we report a complete immunohistological study of two RA patients with RP complications, using a panel of monoclonal antibodies (mAbs) for the recognition of B, T, and NK cells. Both cases showed strong and almost exclusive pericardial membrane infiltration of CD8+ T-cells which was correlated with a higher than expected similar increase in the subset of peripheral blood lymphocytes (PBL). These findings suggest an important role for CD8+ T-cells in chronic RA, especially in this extraarticular manifestation of the disease.

Idioma originalInglés estadounidense
Páginas (desde-hasta)313-316
Número de páginas4
PublicaciónClinical and Experimental Rheumatology
Volumen12
N.º3
EstadoPublicada - 1994
Publicado de forma externa

All Science Journal Classification (ASJC) codes

  • Reumatología
  • Inmulogía y alergología
  • Inmunología

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