TY - JOUR
T1 - Infectious aspects and the etiopathogenesis of rheumatoid arthritis
AU - Meron, Michal Kasher
AU - Amital, Howard
AU - Shepshelovich, Daniel
AU - Barzilai, Ori
AU - Ram, Maya
AU - Anaya, Juan Manuel
AU - Gerli, Roberto
AU - Nicola, Bizzaro
AU - Shoenfeld, Yehuda
N1 - Copyright:
Copyright 2019 Elsevier B.V., All rights reserved.
PY - 2010/4
Y1 - 2010/4
N2 - Infections are believed to contribute to the maturation of the immune system from the innate to the adaptive phases and therefore may take part in the induction of autoimmune conditions. In the current study, we present an extensive analysis conducted on sera samples of patients with rheumatoid arthritis in order to seek evidence of previous or coexisting infectious processes using the Bio-Rad BioPlex immunoassay analyzer. We detected higher rates of serological evidence of infections with Epstein-Barr virus and cytomegalovirus viruses. Our findings may indicate a role of these viruses in the pathogenesis of RA.
AB - Infections are believed to contribute to the maturation of the immune system from the innate to the adaptive phases and therefore may take part in the induction of autoimmune conditions. In the current study, we present an extensive analysis conducted on sera samples of patients with rheumatoid arthritis in order to seek evidence of previous or coexisting infectious processes using the Bio-Rad BioPlex immunoassay analyzer. We detected higher rates of serological evidence of infections with Epstein-Barr virus and cytomegalovirus viruses. Our findings may indicate a role of these viruses in the pathogenesis of RA.
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U2 - 10.1007/s12016-009-8158-6
DO - 10.1007/s12016-009-8158-6
M3 - Article
C2 - 19575154
AN - SCOPUS:77953325452
SN - 1080-0549
VL - 38
SP - 287
EP - 291
JO - Clinical Reviews in Allergy and Immunology
JF - Clinical Reviews in Allergy and Immunology
IS - 2-3
ER -
