Clinical and Serological Characteristics of Ocular Toxoplasmosis in the Democratic Republic of Congo

Nadine Nsiangani Lusambo, Dieudonné Kaimbo Wa Kaimbo, Dieudonné Mumba Ngoyi, Janvier Kilangalanga Ngoy, Marie Thérèse Ngoyi Bambi, Théodore Kadima Mutombo, Guy Kintoki Makela, Lady Ngandowe Nzamokili, Alejandra de-la-Torre

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3 Citas (Scopus)

Resumen

PURPOSE: To describe demographic data, clinical features, and serological profiles in a cohort of Congolese patients with ocular toxoplasmosis (OT).

METHOD: Cross-sectional study, carried out between March 2020 and July 2021 in two ophthalmic clinics in Kinshasa.

RESULTS: The study comprised 95 participants with OT. Fifty-three patients were male (55.8%). The mean age at presentation was 35.6 ± 14.1 years (range 8-69 years); 71 had active OT (74.7%), among them, 33 had primary OT (46.5%), and 38 had recurrences (53.5%). At presentation, 51 patients (53.7%) had visual impairment (VA < 6/18). Retinochoroidal lesions were located in the central retina in 60 patients (63.1%). Patients with primary OT tend to have higher IgG levels than those with recurrent OT ( P = .01).

CONCLUSION: We report the largest cohort of patients with OT in sub-Saharan Africa. In our setting, most patients had recurrent OT with multiple, extensive, and central retinochoroidal lesions.

Idioma originalInglés estadounidense
Páginas (desde-hasta)1-6
Número de páginas6
PublicaciónOcular Immunology and Inflammation
Volumen31
N.º7
DOI
EstadoPublicada - nov. 3 2022

Áreas temáticas de ASJC Scopus

  • Inmulogía y alergología
  • Oftalmología

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