Abstract
Renal involvement in systemic sclerosis (SSc) has a negative influence on prognosis. Cases of SSc sine scleroderma have been reported in which organ failure occurred but was not accompanied by cutaneous damage, which in some instances did develop later. We describe a patient who, after 6 months of symmetric polyarthritis, developed rapid progressive renal failure without skin changes. A diagnosis of scleroderma renal crisis, confirmed histologically, was made. Anti-RNAP m antibodies were positive. The patient developed typical scleroderma skin changes after renal failure. Despite treatment, SSc advanced to fatal endstage renal disease.
Original language | English (US) |
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Pages (from-to) | 557-560 |
Number of pages | 4 |
Journal | Journal of Rheumatology |
Volume | 22 |
Issue number | 3 |
State | Published - 1995 |
Externally published | Yes |
All Science Journal Classification (ASJC) codes
- Rheumatology
- Immunology and Allergy
- Immunology