Simple proteomic checks for detecting noncoding RNA

Stéphane Cruveiller, Oliver Clay, Kamel Jabbari, Giorgio Bernardi

Research output: Contribution to journalArticlepeer-review

5 Scopus citations

Abstract

Proper validation can accelerate sequence-based discovery of proteins and protein-coding genes. Databases currently contain a backlog of experimentally unverified gene models and tentative assignments of observed transcripts to coding or noncoding RNA. We present and apply a general principle, founded on base composition and the genetic code and validated here by bulk 2-D gels, that can improve the reliability of such classifications and of the algorithms or pipelines that lead to them.

Original languageEnglish (US)
Pages (from-to)361-363
Number of pages3
JournalProteomics
Volume7
Issue number3
DOIs
StatePublished - Feb 2007
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Molecular Biology

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