Serologically proven acute rubella infection in patients with clinical diagnosis of dengue

J. Bustos, A. Hamdan, M. A. Loroño, M. T. Montero, B. Gómez

Research output: Contribution to journalResearch Articlepeer-review

10 Scopus citations

Abstract

Patients with a clinical diagnosis of dengue but negative by serological testing were studied for rubella infection. Paired sera were obtained from 69 patients during an outbreak in Yucatán, México. The presence of specific anti-viral IgM in the acute sera was considered as diagnostic for rubella infection. The immunoglobulin was determined by measuring the difference in the inhibition of hemagglutination between the non-reduced and the reduced fractionated sera. Immunoglobulins were separated by sucrose density centrifugation. Acute rubella infection was found in 7 (10·1%) of the patients. These results demonstrate active rubella infection in patients clinically diagnosed as dengue.

Original languageEnglish (US)
Pages (from-to)297-302
Number of pages6
JournalEpidemiology and Infection
Volume104
Issue number2
DOIs
StatePublished - Apr 1990
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Epidemiology
  • Infectious Diseases

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