TY - JOUR
T1 - Musculoskeletal infection in orthopaedic trauma
T2 - Assessment of the 2018 international consensus meeting on musculoskeletal infection
AU - ICM Orthopaedic Trauma Work Group
AU - Obremskey, William T.
AU - Metsemakers, Willem Jan
AU - Schlatterer, Daniel R.
AU - Tetsworth, Kevin
AU - Egol, Kenneth
AU - Kates, Stephen
AU - McNally, Martin
AU - Gibbons, John
AU - Kenny, Paddy
AU - Stangl, Paul
AU - Patzakis, Michael J.
AU - Ferreira, Nando
AU - Tornetta, Paul
AU - Suda, Arnold J.
AU - O'Hara, Nathan
AU - Salles, Mauro Jose Costa
AU - Bhashyam, Abhiram R.
AU - Morgenstern, Mario
AU - Manrique, Jorge
AU - Malizos, Konstantinos N.
AU - Giannoudis, Peter
AU - Nana, Arvind
AU - Egol, Kenneth A.
AU - Kleftouris, George
AU - Reyes, Francisco
AU - Klement, Mitchell R.
AU - Bautista, Maria
AU - Linke, Philip
AU - Citak, Mustafa
AU - Abdelaziz, Hussein
AU - Ecker, Niklas Unter
AU - Suero, Eduardo
AU - Caba, Pedro
AU - Marais, Leonard
AU - Haasper, Carl
AU - Papakostidis, Costas
AU - Natoli, Roman M.
AU - Aldahamsheh, Osama
AU - Abuodeh, Yousef
AU - Quinnan, Stephen
AU - Suarez, Cristina
AU - Conway, Janet D.
AU - Sánchez Correa, Carlos A.
AU - Leal, Jaime A.
AU - Zalavras, Charalampos
AU - Komnos, Georgios
AU - Shope, Alexander J.
AU - Saxena, Arjun
AU - Fram, Brianna
AU - Akesson, Per
N1 - Publisher Copyright:
COPYRIGHT © 2020 BY THE JOURNAL OF BONE AND JOINT SURGERY, INCORPORATED
PY - 2020/5/20
Y1 - 2020/5/20
N2 - Fracture-related infections (FRIs) are among the most common complications following fracture fixation, and they have a huge economic and functional impact on patients. Because consensus guidelines with respect to prevention, diagnosis, and treatment of this major complication are scarce, delegates from different countries gathered in Philadelphia in July 2018 as part of the Second International Consensus Meeting (ICM) on Musculoskeletal Infection. This paper summarizes the discussion and recommendations from that consensus meeting, using the Delphi technique, with a focus on FRIs. A standardized definition that was based on diagnostic criteria was endorsed, which will hopefully improve reporting and research on FRIs in the future. Furthermore, this paper provides a grade of evidence (strong, moderate, limited, or consensus) for strategies and practices that prevent and treat infection. The grade of evidence is based on the quality of evidence as utilized by the American Academy of Orthopaedic Surgeons. The guidelines presented herein focus not only on the appropriate use of antibiotics, but also on practices for the timing of fracture fixation, soft-tissue coverage, and bone defect and hardware management. We hope that this summary as well as the full document by the International Consensus Group are utilized by those who are charged with musculoskeletal care internationally to optimize their management strategies for the prevention and treatment of FRIs.
AB - Fracture-related infections (FRIs) are among the most common complications following fracture fixation, and they have a huge economic and functional impact on patients. Because consensus guidelines with respect to prevention, diagnosis, and treatment of this major complication are scarce, delegates from different countries gathered in Philadelphia in July 2018 as part of the Second International Consensus Meeting (ICM) on Musculoskeletal Infection. This paper summarizes the discussion and recommendations from that consensus meeting, using the Delphi technique, with a focus on FRIs. A standardized definition that was based on diagnostic criteria was endorsed, which will hopefully improve reporting and research on FRIs in the future. Furthermore, this paper provides a grade of evidence (strong, moderate, limited, or consensus) for strategies and practices that prevent and treat infection. The grade of evidence is based on the quality of evidence as utilized by the American Academy of Orthopaedic Surgeons. The guidelines presented herein focus not only on the appropriate use of antibiotics, but also on practices for the timing of fracture fixation, soft-tissue coverage, and bone defect and hardware management. We hope that this summary as well as the full document by the International Consensus Group are utilized by those who are charged with musculoskeletal care internationally to optimize their management strategies for the prevention and treatment of FRIs.
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U2 - 10.2106/JBJS.19.01070
DO - 10.2106/JBJS.19.01070
M3 - Research Article
C2 - 32118653
AN - SCOPUS:85085264308
SN - 0021-9355
VL - 102
SP - E441-E449
JO - Journal of Bone and Joint Surgery - American Volume
JF - Journal of Bone and Joint Surgery - American Volume
IS - 10
ER -