Anemia aplastica. Tratamento alternativo a transplantacao medular

Translated title of the contribution: Aplastic anemia - Alternative treatment to bone marrow transplantation

T. Fonseca, J. Raposo, B. Gomez, J. J.G. D'Oliveira, J. M. Forjaz De Lacerda

Research output: Contribution to journalArticlepeer-review


We report a case of a 25-year-old woman, with the diagnosis of severe aplastic anemia without a histocompatible sibling donor for bone marrow transplantation. The patient has been treated successfully with a combination of two immunosuppressive agents, cyclosporine and antilymphocyte globulin, after not responding to primary therapy with corticosteroids and growth factors. She showed a complete response to treatment, with transfusional independence, after a follow-up of 14 months. The pathophysiology of aplastic anemia, the mechanism of action and secondary effects of these treatments are discussed.

Translated title of the contributionAplastic anemia - Alternative treatment to bone marrow transplantation
Original languagePortuguese
Pages (from-to)99-102
Number of pages4
JournalActa Medica Portuguesa
Issue number1
StatePublished - 1997
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • General Medicine


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