Abstract
We report a case of a 25-year-old woman, with the diagnosis of severe aplastic anemia without a histocompatible sibling donor for bone marrow transplantation. The patient has been treated successfully with a combination of two immunosuppressive agents, cyclosporine and antilymphocyte globulin, after not responding to primary therapy with corticosteroids and growth factors. She showed a complete response to treatment, with transfusional independence, after a follow-up of 14 months. The pathophysiology of aplastic anemia, the mechanism of action and secondary effects of these treatments are discussed.
| Translated title of the contribution | Aplastic anemia - Alternative treatment to bone marrow transplantation |
|---|---|
| Original language | Portuguese |
| Pages (from-to) | 99-102 |
| Number of pages | 4 |
| Journal | Acta Medica Portuguesa |
| Volume | 10 |
| Issue number | 1 |
| State | Published - 1997 |
| Externally published | Yes |
All Science Journal Classification (ASJC) codes
- General Medicine