Ácido úrico herramienta de tamización para preeclampsia. Una revisión sistemática de la literatura

Translated title of the contribution: Uric acid screening tool for preeclampsia a systematic review

A. M. Pedraza Flechas, M.F. Toro Wills, L.C. Sánchez Valencia, V.S. Rangel Ramos, M.C. Martínez Ávila

Research output: Contribution to journalResearch Articlepeer-review


Introduction: Uric acid has been described as a possible risk marker for the appearance of pre-eclampsia. However, so far there is no solid evidence to support it. The objective of this study is to synthesize the available literature to determine the usefulness of uric acid as a screening tool for pre-eclampsia.

Methodology: Systematic review of the literature of primary studies that analyse serum uric acid levels in the first and second trimesters of gestation with the development of pre-eclampsia. Search in PubMed (n: 639).

Results: Two studies (2 cohort studies) were included with a total of 9,746 pregnant women and 398 cases of pre-eclampsia. In the studies, higher serum uric acid levels were found in pregnant women who developed preeclampsia (OR 1.8 to 2.0).

Conclusions: Uric acid is related to the presence of preeclampsia and its pathophysiology. The scientific community is invited to continue investigating the applicability of uric acid for its implementation as a screening tool in the first and second trimester of pregnancy.

Translated title of the contributionUric acid screening tool for preeclampsia a systematic review
Original languageSpanish (Colombia)
Article number100749
Pages (from-to)1-6
Number of pages6
JournalClinica e Investigacion en Ginecologia y Obstetricia
Issue number3
StatePublished - Jul 1 2022

All Science Journal Classification (ASJC) codes

  • Reproductive Medicine
  • Obstetrics and Gynecology


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