Resumen
The aim of this study is to assess the time-dependent mechanical properties of rat femoral cortical bone in a lifespan model from growth to senescence. New nanoindentation protocol was performed to assess the time-dependent mechanical behavior. The experimental data were fitted with an elastic-viscoelastic- plastic-viscoplastic mechanical model allowing the calculus of the mechanical properties. Variation of mechanical response of bone as a function of the strain rate and age were highlighted. The most representative variations of the mechanical properties with age were found to be statistically significant (P < 0.001) from 1 to 4 months for elastic properties, from 1 to 9 months for viscoelastic properties and during all lifespan for plastic and viscoplastic properties, highlighting different maturation ages for elastic, viscoelastic, plastic and viscoplastic behaviors. These results suggest that different physical-chemical and structural processes occur at different ages reflecting bone modeling and remodeling activities in the rat's whole lifespan.
Idioma original | Inglés estadounidense |
---|---|
Páginas (desde-hasta) | 1135-1143 |
Número de páginas | 9 |
Publicación | Journal of Materials Research |
Volumen | 29 |
N.º | 10 |
DOI | |
Estado | Publicada - may. 28 2014 |
Publicado de forma externa | Sí |
Áreas temáticas de ASJC Scopus
- Ciencia de los Materiales General
- Física de la materia condensada
- Mecánica de materiales
- Ingeniería mecánica