TY - JOUR
T1 - Sleep patterns, sleep disorders and mammographic density in spanish women
T2 - The DDM-Spain/Var-DDM study
AU - Pedraza-Flechas, Ana María
AU - Lope, Virginia
AU - Moreo, Pilar
AU - Ascunce, Nieves
AU - Miranda-García, Josefa
AU - Vidal, Carmen
AU - Sánchez-Contador, Carmen
AU - Santamariña, Carmen
AU - Pedraz-Pingarrón, Carmen
AU - Llobet, Rafael
AU - Aragonés, Nuria
AU - Salas-Trejo, Dolores
AU - Pollán, Marina
AU - Pérez-Gómez, Beatriz
N1 - Funding Information:
This work was supported by grants from the Spanish Ministry of Economy and Competitiveness − Carlos III Institute of Health (ISCIII) (FI14CIII/00013, FIS PI060386 & PS09/0790), from the Spanish Federation of Breast Cancer Patients (FECMA 485 EPY 1170–10), Gent per Gent Fund (EDEMAC Project), the EPY1306/06 collaboration agreement between Astra-Zeneca and the ISCIII and partially funded by the European Regional Development Fund (FEDER).
Publisher Copyright:
© 2017 Elsevier B.V.
PY - 2017/5/1
Y1 - 2017/5/1
N2 - We explored the relationship between sleep patterns and sleep disorders and mammographic density (MD), a marker of breast cancer risk. Participants in the DDM-Spain/var-DDM study, which included 2878 middle-aged Spanish women, were interviewed via telephone and asked questions on sleep characteristics. Two radiologists assessed MD in their left craneo-caudal mammogram, assisted by a validated semiautomatic-computer tool (DM-scan). We used log-transformed percentage MD as the dependent variable and fitted mixed linear regression models, including known confounding variables. Our results showed that neither sleeping patterns nor sleep disorders were associated with MD. However, women with frequent changes in their bedtime due to anxiety or depression had higher MD (eβ:1.53;95%CI:1.04–2.26).
AB - We explored the relationship between sleep patterns and sleep disorders and mammographic density (MD), a marker of breast cancer risk. Participants in the DDM-Spain/var-DDM study, which included 2878 middle-aged Spanish women, were interviewed via telephone and asked questions on sleep characteristics. Two radiologists assessed MD in their left craneo-caudal mammogram, assisted by a validated semiautomatic-computer tool (DM-scan). We used log-transformed percentage MD as the dependent variable and fitted mixed linear regression models, including known confounding variables. Our results showed that neither sleeping patterns nor sleep disorders were associated with MD. However, women with frequent changes in their bedtime due to anxiety or depression had higher MD (eβ:1.53;95%CI:1.04–2.26).
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U2 - 10.1016/j.maturitas.2017.02.015
DO - 10.1016/j.maturitas.2017.02.015
M3 - Article
C2 - 28364862
AN - SCOPUS:85014849803
SN - 0378-5122
VL - 99
SP - 105
EP - 108
JO - Maturitas
JF - Maturitas
ER -
