Selective sweeps on novel and introgressed variation shape mimicry loci in a butterfly adaptive radiation

Markus Moest; Steven M. Van Belleghem; Jennifer E. James; Camilo Salazar; Simon H. Martin; Sarah L. Barker; Gilson R.P. Moreira; Claire Merot; Mathieu Joron; Nicola J. Nadeau; Florian M. Steiner; Chris D. Jiggins

doi:10.1371/journal.pbio.3000597

Selective sweeps on novel and introgressed variation shape mimicry loci in a butterfly adaptive radiation

Título traducido de la contribución: Barridos selectivos en nuevos loci introgresados moldean la variación de los genes del mimetismo en una radiación adaptative de mariposas

Markus Moest, Steven M. Van Belleghem, Jennifer E. James, Camilo Salazar, Simon H. Martin, Sarah L. Barker, Gilson R.P. Moreira, Claire Merot, Mathieu Joron, Nicola J. Nadeau, Florian M. Steiner, Chris D. Jiggins

Producción científica: Contribución a una revista › Artículo de Investigación › revisión exhaustiva

45 Citas (Scopus)

Resumen

La selección natural deja firmas distintivas en el genoma que pueden revelar regiones blanco y la historia de la evolución adaptativa. Al analizar los datos de la secuencia del genoma de alta cobertura de 4 loci principales de patrones de color muestreados de casi 600 individuos en 53 poblaciones, mostramos una selección generalizada en los patrones de las alas en la radiación adaptativa de Heliconius. Las firmas más fuertes corresponden a loci con los mayores efectos fenotípicos, consistentes con la selección visual por parte de los depredadores, y se encuentran en patrones de color con distribuciones geográficamente restringidas. Estos barridos recientes son similares entre los co-mímicos e indican eventos de cambio de patrones de color a pesar de la fuerte selección estabilizadora. Utilizando simulaciones, comparamos las firmas de barrido esperadas en los barridos duros clásicos con las resultantes de la introgresión adaptativa, un aspecto importante de la evolución del mimetismo en las mariposas Heliconius. Las poblaciones receptoras simuladas muestran un patrón de "volcán" distintivo con picos de aumento de la diversidad genética alrededor de la región seleccionada, característico de los barridos de variación introgresada y consistente con los patrones de diversidad encontrados en algunas poblaciones. Nuestros datos genómicos revelan una historia sorprendentemente dinámica de selección de patrones de color y coevolución en esta radiación adaptativa.

Título traducido de la contribución	Barridos selectivos en nuevos loci introgresados moldean la variación de los genes del mimetismo en una radiación adaptative de mariposas
Idioma original	Inglés estadounidense
Número de artículo	e3000597
Número de páginas	37
Publicación	PLoS Biology
Volumen	18
N.º	2
DOI	https://doi.org/10.1371/journal.pbio.3000597
Estado	Publicada - feb. 6 2020

Áreas temáticas de ASJC Scopus

Neurociencias General
Bioquímica, Genética y Biología Molecular General
Inmunología y Microbiología General
Ciencias Agrícolas y Biológicas General

Acceder al documento

10.1371/journal.pbio.3000597

https://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.3000597

Otros archivos y enlaces

Citar esto

Moest, M., Van Belleghem, S. M., James, J. E., Salazar, C., Martin, S. H., Barker, S. L., Moreira, G. R. P., Merot, C., Joron, M., Nadeau, N. J., Steiner, F. M., & Jiggins, C. D. (2020). Selective sweeps on novel and introgressed variation shape mimicry loci in a butterfly adaptive radiation. PLoS Biology, 18(2), Artículo e3000597. https://doi.org/10.1371/journal.pbio.3000597

@article{40b7752800a042d8877cf616d99095dd,

title = "Selective sweeps on novel and introgressed variation shape mimicry loci in a butterfly adaptive radiation",

abstract = "Natural selection leaves distinct signatures in the genome that can reveal the targets and history of adaptive evolution. By analysing high-coverage genome sequence data from 4 major colour pattern loci sampled from nearly 600 individuals in 53 populations, we show pervasive selection on wing patterns in the Heliconius adaptive radiation. The strongest signatures correspond to loci with the greatest phenotypic effects, consistent with visual selection by predators, and are found in colour patterns with geographically restricted distributions. These recent sweeps are similar between co-mimics and indicate colour pattern turn-over events despite strong stabilising selection. Using simulations, we compare sweep signatures expected under classic hard sweeps with those resulting from adaptive introgression, an important aspect of mimicry evolution in Heliconius butterflies. Simulated recipient populations show a distinct 'volcano' pattern with peaks of increased genetic diversity around the selected target, characteristic of sweeps of introgressed variation and consistent with diversity patterns found in some populations. Our genomic data reveal a surprisingly dynamic history of colour pattern selection and co-evolution in this adaptive radiation.",

author = "Markus Moest and {Van Belleghem}, {Steven M.} and James, {Jennifer E.} and Camilo Salazar and Martin, {Simon H.} and Barker, {Sarah L.} and Moreira, {Gilson R.P.} and Claire Merot and Mathieu Joron and Nadeau, {Nicola J.} and Steiner, {Florian M.} and Jiggins, {Chris D.}",

note = "Publisher Copyright: {\textcopyright} 2020 Moest et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.",

year = "2020",

month = feb,

day = "6",

doi = "10.1371/journal.pbio.3000597",

language = "English (US)",

volume = "18",

journal = "PLoS Biology",

issn = "1544-9173",

publisher = "Public Library of Science",

number = "2",

}

TY - JOUR

T1 - Selective sweeps on novel and introgressed variation shape mimicry loci in a butterfly adaptive radiation

AU - Moest, Markus

AU - Van Belleghem, Steven M.

AU - James, Jennifer E.

AU - Salazar, Camilo

AU - Martin, Simon H.

AU - Barker, Sarah L.

AU - Moreira, Gilson R.P.

AU - Merot, Claire

AU - Joron, Mathieu

AU - Nadeau, Nicola J.

AU - Steiner, Florian M.

AU - Jiggins, Chris D.

N1 - Publisher Copyright: © 2020 Moest et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

PY - 2020/2/6

Y1 - 2020/2/6

N2 - Natural selection leaves distinct signatures in the genome that can reveal the targets and history of adaptive evolution. By analysing high-coverage genome sequence data from 4 major colour pattern loci sampled from nearly 600 individuals in 53 populations, we show pervasive selection on wing patterns in the Heliconius adaptive radiation. The strongest signatures correspond to loci with the greatest phenotypic effects, consistent with visual selection by predators, and are found in colour patterns with geographically restricted distributions. These recent sweeps are similar between co-mimics and indicate colour pattern turn-over events despite strong stabilising selection. Using simulations, we compare sweep signatures expected under classic hard sweeps with those resulting from adaptive introgression, an important aspect of mimicry evolution in Heliconius butterflies. Simulated recipient populations show a distinct 'volcano' pattern with peaks of increased genetic diversity around the selected target, characteristic of sweeps of introgressed variation and consistent with diversity patterns found in some populations. Our genomic data reveal a surprisingly dynamic history of colour pattern selection and co-evolution in this adaptive radiation.

AB - Natural selection leaves distinct signatures in the genome that can reveal the targets and history of adaptive evolution. By analysing high-coverage genome sequence data from 4 major colour pattern loci sampled from nearly 600 individuals in 53 populations, we show pervasive selection on wing patterns in the Heliconius adaptive radiation. The strongest signatures correspond to loci with the greatest phenotypic effects, consistent with visual selection by predators, and are found in colour patterns with geographically restricted distributions. These recent sweeps are similar between co-mimics and indicate colour pattern turn-over events despite strong stabilising selection. Using simulations, we compare sweep signatures expected under classic hard sweeps with those resulting from adaptive introgression, an important aspect of mimicry evolution in Heliconius butterflies. Simulated recipient populations show a distinct 'volcano' pattern with peaks of increased genetic diversity around the selected target, characteristic of sweeps of introgressed variation and consistent with diversity patterns found in some populations. Our genomic data reveal a surprisingly dynamic history of colour pattern selection and co-evolution in this adaptive radiation.

UR - http://www.scopus.com/inward/record.url?scp=85080846797&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85080846797&partnerID=8YFLogxK

U2 - 10.1371/journal.pbio.3000597

DO - 10.1371/journal.pbio.3000597

M3 - Research Article

C2 - 32027643

AN - SCOPUS:85080846797

SN - 1544-9173

VL - 18

JO - PLoS Biology

JF - PLoS Biology

IS - 2

M1 - e3000597

ER -

Selective sweeps on novel and introgressed variation shape mimicry loci in a butterfly adaptive radiation

Resumen

Áreas temáticas de ASJC Scopus

Acceder al documento

Otros archivos y enlaces

Huella

Citar esto