Non-invasive assessment of β-carotene levels in the skin of colombian adults

Robinson Ramírez-Vélez, Katherine González-Ruiz, Sophya García, Carlos Alejandro López-Alban, Natalia Escudero, Ricardo Antonio Agredo-Zúñiga

Resultado de la investigación: Contribución a RevistaArtículo

Resumen

Introduction: Carotenoid pigments have antioxidant properties beneficial for human health. Use of resonance Raman spectroscopy (RRS) as a reliable method for measuring carotenoid levels in tissues such as dermis has been suggested. However, data about the variability and reproducibility of this technique should be collected before it can be used. Objective: To assess reproducibility of RRS for detection of total β-carotene levels in the skin of Colombian adults. Design: Forty-eight healthy men and 30 healthy women with various pigmentation levels were enrolled into the study. Measurements by RRS were performed in the palmar region and medial and lateral aspects of the arms. Odds ratio and 95% confidence intervals were calculated, adjusting for confounding factors: body mass index, waist circumference, percent body fat, age, race, smoking, and sex. Reproducibility of the technique was estimated using intraclass correlation coefficient (ICC). Results: Mean β-carotene levels were 29.9±11.9 in men and 30.6±8.6 in women (. P=.787). No differences or significant associations were found of β-carotene levels with confounding factors assessed by sex. ICCs were 0.89 in the palmar region, 0.85 in the medial aspect of arm, and 0.82 in the external aspect of arm. Conclusion: RRS spectroscopy is a reliable method for non-invasive measurement of β-carotene levels in skin, and may be used as an important biomarker of antioxidant status in nutritional and health studies in humans. © 2012 SEEN.
Idioma originalEnglish (US)
Páginas (desde-hasta)304-310
Número de páginas7
PublicaciónEndocrinologia y Nutricion
DOI
EstadoPublished - may 1 2012

Huella dactilar

Raman Spectrum Analysis
beta Carotene
Skin
Carotenoids
Antioxidants
Sex Factors
Pigmentation
Waist Circumference
Dermis
Nutritional Status
Health Status
Adipose Tissue
Spectrum Analysis
Body Mass Index
Biomarkers
Smoking
Odds Ratio
Confidence Intervals
Health

Citar esto

Ramírez-Vélez, R., González-Ruiz, K., García, S., López-Alban, C. A., Escudero, N., & Agredo-Zúñiga, R. A. (2012). Non-invasive assessment of β-carotene levels in the skin of colombian adults. Endocrinologia y Nutricion, 304-310. https://doi.org/10.1016/j.endonu.2012.03.001
Ramírez-Vélez, Robinson ; González-Ruiz, Katherine ; García, Sophya ; López-Alban, Carlos Alejandro ; Escudero, Natalia ; Agredo-Zúñiga, Ricardo Antonio. / Non-invasive assessment of β-carotene levels in the skin of colombian adults. En: Endocrinologia y Nutricion. 2012 ; pp. 304-310.
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title = "Non-invasive assessment of β-carotene levels in the skin of colombian adults",
abstract = "Introduction: Carotenoid pigments have antioxidant properties beneficial for human health. Use of resonance Raman spectroscopy (RRS) as a reliable method for measuring carotenoid levels in tissues such as dermis has been suggested. However, data about the variability and reproducibility of this technique should be collected before it can be used. Objective: To assess reproducibility of RRS for detection of total β-carotene levels in the skin of Colombian adults. Design: Forty-eight healthy men and 30 healthy women with various pigmentation levels were enrolled into the study. Measurements by RRS were performed in the palmar region and medial and lateral aspects of the arms. Odds ratio and 95{\%} confidence intervals were calculated, adjusting for confounding factors: body mass index, waist circumference, percent body fat, age, race, smoking, and sex. Reproducibility of the technique was estimated using intraclass correlation coefficient (ICC). Results: Mean β-carotene levels were 29.9±11.9 in men and 30.6±8.6 in women (. P=.787). No differences or significant associations were found of β-carotene levels with confounding factors assessed by sex. ICCs were 0.89 in the palmar region, 0.85 in the medial aspect of arm, and 0.82 in the external aspect of arm. Conclusion: RRS spectroscopy is a reliable method for non-invasive measurement of β-carotene levels in skin, and may be used as an important biomarker of antioxidant status in nutritional and health studies in humans. {\circledC} 2012 SEEN.",
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Ramírez-Vélez, R, González-Ruiz, K, García, S, López-Alban, CA, Escudero, N & Agredo-Zúñiga, RA 2012, 'Non-invasive assessment of β-carotene levels in the skin of colombian adults', Endocrinologia y Nutricion, pp. 304-310. https://doi.org/10.1016/j.endonu.2012.03.001

Non-invasive assessment of β-carotene levels in the skin of colombian adults. / Ramírez-Vélez, Robinson; González-Ruiz, Katherine; García, Sophya; López-Alban, Carlos Alejandro; Escudero, Natalia; Agredo-Zúñiga, Ricardo Antonio.

En: Endocrinologia y Nutricion, 01.05.2012, p. 304-310.

Resultado de la investigación: Contribución a RevistaArtículo

TY - JOUR

T1 - Non-invasive assessment of β-carotene levels in the skin of colombian adults

AU - Ramírez-Vélez, Robinson

AU - González-Ruiz, Katherine

AU - García, Sophya

AU - López-Alban, Carlos Alejandro

AU - Escudero, Natalia

AU - Agredo-Zúñiga, Ricardo Antonio

PY - 2012/5/1

Y1 - 2012/5/1

N2 - Introduction: Carotenoid pigments have antioxidant properties beneficial for human health. Use of resonance Raman spectroscopy (RRS) as a reliable method for measuring carotenoid levels in tissues such as dermis has been suggested. However, data about the variability and reproducibility of this technique should be collected before it can be used. Objective: To assess reproducibility of RRS for detection of total β-carotene levels in the skin of Colombian adults. Design: Forty-eight healthy men and 30 healthy women with various pigmentation levels were enrolled into the study. Measurements by RRS were performed in the palmar region and medial and lateral aspects of the arms. Odds ratio and 95% confidence intervals were calculated, adjusting for confounding factors: body mass index, waist circumference, percent body fat, age, race, smoking, and sex. Reproducibility of the technique was estimated using intraclass correlation coefficient (ICC). Results: Mean β-carotene levels were 29.9±11.9 in men and 30.6±8.6 in women (. P=.787). No differences or significant associations were found of β-carotene levels with confounding factors assessed by sex. ICCs were 0.89 in the palmar region, 0.85 in the medial aspect of arm, and 0.82 in the external aspect of arm. Conclusion: RRS spectroscopy is a reliable method for non-invasive measurement of β-carotene levels in skin, and may be used as an important biomarker of antioxidant status in nutritional and health studies in humans. © 2012 SEEN.

AB - Introduction: Carotenoid pigments have antioxidant properties beneficial for human health. Use of resonance Raman spectroscopy (RRS) as a reliable method for measuring carotenoid levels in tissues such as dermis has been suggested. However, data about the variability and reproducibility of this technique should be collected before it can be used. Objective: To assess reproducibility of RRS for detection of total β-carotene levels in the skin of Colombian adults. Design: Forty-eight healthy men and 30 healthy women with various pigmentation levels were enrolled into the study. Measurements by RRS were performed in the palmar region and medial and lateral aspects of the arms. Odds ratio and 95% confidence intervals were calculated, adjusting for confounding factors: body mass index, waist circumference, percent body fat, age, race, smoking, and sex. Reproducibility of the technique was estimated using intraclass correlation coefficient (ICC). Results: Mean β-carotene levels were 29.9±11.9 in men and 30.6±8.6 in women (. P=.787). No differences or significant associations were found of β-carotene levels with confounding factors assessed by sex. ICCs were 0.89 in the palmar region, 0.85 in the medial aspect of arm, and 0.82 in the external aspect of arm. Conclusion: RRS spectroscopy is a reliable method for non-invasive measurement of β-carotene levels in skin, and may be used as an important biomarker of antioxidant status in nutritional and health studies in humans. © 2012 SEEN.

U2 - 10.1016/j.endonu.2012.03.001

DO - 10.1016/j.endonu.2012.03.001

M3 - Article

SP - 304

EP - 310

JO - Endocrinologia, Diabetes y Nutricion

JF - Endocrinologia, Diabetes y Nutricion

SN - 2530-0164

ER -

Ramírez-Vélez R, González-Ruiz K, García S, López-Alban CA, Escudero N, Agredo-Zúñiga RA. Non-invasive assessment of β-carotene levels in the skin of colombian adults. Endocrinologia y Nutricion. 2012 may 1;304-310. https://doi.org/10.1016/j.endonu.2012.03.001