TY - JOUR
T1 - Lipid Metabolism of Leukocytes at unstimulated and activated state.
AU - Alarcón, Juan Carlos
AU - H. von Hegedus, Johannes
AU - Brouwers, Hilde
AU - Steenvoorden, Evelyne
AU - Ioan-Facsinay, Andreea
AU - Mayboroda, Oleg
AU - Ondo-Méndez, Alejandro
AU - Giera, Martin
PY - 2020/2/14
Y1 - 2020/2/14
N2 - ipidomics has emerged as a powerful technique to study cellular lipid metabolism. As the lipidome contains numerous isomeric and isobaric species resulting in a significant overlap between different lipid classes, cutting-edge analytical technology is necessary for a comprehensive analysis of lipid metabolism. Just recently, differential mobility spectrometry (DMS) has evolved as such a technology, helping to overcome several analytical challenges. We here set out to apply DMS and the Lipidyzer™ platform to obtain a comprehensive overview of leukocyte-related lipid metabolism in the resting and activated states
AB - ipidomics has emerged as a powerful technique to study cellular lipid metabolism. As the lipidome contains numerous isomeric and isobaric species resulting in a significant overlap between different lipid classes, cutting-edge analytical technology is necessary for a comprehensive analysis of lipid metabolism. Just recently, differential mobility spectrometry (DMS) has evolved as such a technology, helping to overcome several analytical challenges. We here set out to apply DMS and the Lipidyzer™ platform to obtain a comprehensive overview of leukocyte-related lipid metabolism in the resting and activated states
U2 - 10.1007/s00216-020-02460-8
DO - 10.1007/s00216-020-02460-8
M3 - Artículo
C2 - 32055910
SN - 0016-1152
SP - 2353
EP - 2363
JO - Analytical and Bioanalytical Chemistry
JF - Analytical and Bioanalytical Chemistry
ER -