Project Details
Description
Aortic dissection and aneurysms are diseases that are characterized by a low incidence and prevalence, but high rates of morbidity and mortality, as well as high social impact because they are associated with complex procedures that usually require long periods of highly complex and high hospitalization. costs, for this reason, its prevention and timely diagnosis are fundamental pillars on which the efforts of the health system must focus.
Given that most aortic diseases have a complex etiopathogenesis, the identification of associated factors has been one of the focuses of research in this area.
So far, the following have been identified: gender, advanced age, high blood pressure, smoking, collagen diseases, vasculitis and injuries to the aorta either due to trauma or surgery.
Recent reports have related anatomical variations of the aortic arch with the occurrence of aortic dissection, however, the results have been contradictory.
This study seeks to determine if there is an association between anatomical variations of the aortic arch with aneurysms and dissections of the ascending aorta, the aortic arch and the thoracic aorta.
Taking into account that these are rare conditions, a case-control study is proposed.
The medical records of patients over 18 years of age who were admitted to Méderi and Fundación Cardioinfantil-Institute of Cardiology, with a suspected diagnosis of aortic pathology and who underwent ANGIOTAC or angio-resonance, between 2010 and 2019 will be studied.
Patients whose diagnosis of aortic aneurysm or dissection in the aforementioned locations is confirmed by these means will be considered cases, while those who are ruled out will be considered controls.
On the other hand, it is also intended to carry out a diagnostic test study to evaluate the agreement and operating characteristics of ultrasonography for determining the diameter of the abdominal aorta and for detecting aneurysms of the infra and adrenal abdominal aorta, with respect to ANGIOTAC as gold standard.
Given that most aortic diseases have a complex etiopathogenesis, the identification of associated factors has been one of the focuses of research in this area.
So far, the following have been identified: gender, advanced age, high blood pressure, smoking, collagen diseases, vasculitis and injuries to the aorta either due to trauma or surgery.
Recent reports have related anatomical variations of the aortic arch with the occurrence of aortic dissection, however, the results have been contradictory.
This study seeks to determine if there is an association between anatomical variations of the aortic arch with aneurysms and dissections of the ascending aorta, the aortic arch and the thoracic aorta.
Taking into account that these are rare conditions, a case-control study is proposed.
The medical records of patients over 18 years of age who were admitted to Méderi and Fundación Cardioinfantil-Institute of Cardiology, with a suspected diagnosis of aortic pathology and who underwent ANGIOTAC or angio-resonance, between 2010 and 2019 will be studied.
Patients whose diagnosis of aortic aneurysm or dissection in the aforementioned locations is confirmed by these means will be considered cases, while those who are ruled out will be considered controls.
On the other hand, it is also intended to carry out a diagnostic test study to evaluate the agreement and operating characteristics of ultrasonography for determining the diameter of the abdominal aorta and for detecting aneurysms of the infra and adrenal abdominal aorta, with respect to ANGIOTAC as gold standard.
| Status | Finished |
|---|---|
| Effective start/end date | 7/16/20 → 7/16/23 |
UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This project contributes towards the following SDG(s):
Main Funding Source
- National
Location
- Bogotá D.C.
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