Vogt–Koyanagi–Harada Syndrome in a Group of Patients in Two Ophthalmology Referral Centers in Bogotá, Colombia: VKH syndrome in Colombia

Ligia Alejandra De La Torre Cifuentes; Carol Guayacán; Brahyan Galindo-Mendez

doi:10.1080/09273948.2017.1341536

Vogt–Koyanagi–Harada Syndrome in a Group of Patients in Two Ophthalmology Referral Centers in Bogotá, Colombia: VKH syndrome in Colombia

Título traducido de la contribución: Síndrome de Vogt-Koyanagi-Harada en un grupo de pacientes en dos centros de referencia de oftalmología en Bogotá, Colombia.

Ligia Alejandra De La Torre Cifuentes
, Carol Guayacán
, Brahyan Galindo-Mendez

Producción científica: Contribución a revista › Artículo de Investigación › revisión exhaustiva

9 Citas (Scopus)

Resumen

Objetivo: describir la presentación clínica del síndrome de Vogt-Koyanagi-Harada en un grupo de pacientes en Colombia.
Métodos: Revisión retrospectiva de 2638 historias clínicas de pacientes con uveítis en dos centros durante 17 años. Los pacientes con síndrome de Vogt-Koyanagi-Harada se reunieron para caracterizar datos demográficos y clínicos.
Resultados: Veinticinco pacientes con uveítis fueron diagnosticados con síndrome de Vogt-Koyanagi-Harada (0,95%), 78,3% mujeres, con una edad media de diagnóstico de 37 años (SD ± 29). Veintitrés pacientes con datos completos fueron incluidos. Principales quejas: visión borrosa (87%), dolores de cabeza (47.8%), tinnitus (26.1%) y deficiencias auditivas (21.7%). Hallazgos oftálmicos: desprendimiento de retina seroso bilateral (67.4%), uveítis no granulomatosa (52.3%). La mayoría de los pacientes fueron diagnosticados con enfermedad probable (56.5%). La duración promedio del seguimiento fue de catorce meses; la recaída de la enfermedad se encontró en el 26% de los pacientes a pesar del tratamiento.
Conclusión: Los pacientes en Colombia con Vogt-Koyanagi-Harada tenían características clínicas similares a las informadas en otras poblaciones hispanas, a excepción de la uveítis no granulomatosa. Se puede considerar que esta enfermedad tiene variación en las manifestaciones clínicas entre los grupos de población

Título traducido de la contribución	Síndrome de Vogt-Koyanagi-Harada en un grupo de pacientes en dos centros de referencia de oftalmología en Bogotá, Colombia.
Idioma original	Inglés estadounidense
Número de artículo	NOII 2016-0391
Páginas (desde-hasta)	1-13
Número de páginas	13
Publicación	Ocular Immunology and Inflammation
Volumen	26
N.º	7
DOI	https://doi.org/10.1080/09273948.2017.1341536
Estado	Publicada - sept 14 2017

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@article{ac5ae82b00204cb38dad7413b3ceec8b,

title = "Vogt–Koyanagi–Harada Syndrome in a Group of Patients in Two Ophthalmology Referral Centers in Bogot{\'a}, Colombia: VKH syndrome in Colombia",

abstract = "Purpose: To describe the clinical presentation of Vogt-Koyanagi-Harada syndrome in a group of patients in Colombia. Methods: Retrospective-review of 2638 medical-records of patients with uveitis in two centers during 17 years. Patients with Vogt-Koyanagi-Harada syndrome were gathered to characterize demographic and clinical data. Results: Twenty-five patients with uveitis were diagnosed with Vogt-Koyanagi-Harada syndrome (0.95\%), 78.3\% females, mean age of diagnosis 37 years old (SD ±29). Twenty-three patients with complete data were included. Main complaints: blurred vision (87\%), headaches (47.8\%), tinnitus (26.1\%) and hearing impairments (21.7\%). Ophthalmic findings: bilateral serous retinal-detachment (67.4\%), non-granulomatous uveitis (52.3\%). Most of the patients were diagnosed with probable disease (56.5\%). Mean duration of follow-up was fourteen months; disease relapse was encountered in 26\% of patients despite treatment. Conclusion: Patients in Colombia with Vogt-Koyanagi-Harada had clinical features similar to those reported in other Hispanic populations, except for the non-granulomatous uveitis. This disease may be considered as having variation of clinical manifestations across population groups. ",

author = "\{De La Torre Cifuentes\}, \{Ligia Alejandra\} and Carol Guayac{\'a}n and Brahyan Galindo-Mendez",

year = "2017",

month = sep,

day = "14",

doi = "10.1080/09273948.2017.1341536",

language = "English (US)",

volume = "26",

pages = "1--13",

journal = "Ocular Immunology and Inflammation",

issn = "0927-3948",

publisher = "Taylor and Francis Ltd.",

number = "7",

}

Vogt–Koyanagi–Harada Syndrome in a Group of Patients in Two Ophthalmology Referral Centers in Bogotá, Colombia: VKH syndrome in Colombia. / De La Torre Cifuentes, Ligia Alejandra; Guayacán, Carol; Galindo-Mendez, Brahyan.
En: Ocular Immunology and Inflammation, Vol. 26, N.º 7, NOII 2016-0391, 14.09.2017, p. 1-13.

Producción científica: Contribución a revista › Artículo de Investigación › revisión exhaustiva

TY - JOUR

T1 - Vogt–Koyanagi–Harada Syndrome in a Group of Patients in Two Ophthalmology Referral Centers in Bogotá, Colombia

T2 - VKH syndrome in Colombia

AU - De La Torre Cifuentes, Ligia Alejandra

AU - Guayacán, Carol

AU - Galindo-Mendez, Brahyan

PY - 2017/9/14

Y1 - 2017/9/14

N2 - Purpose: To describe the clinical presentation of Vogt-Koyanagi-Harada syndrome in a group of patients in Colombia. Methods: Retrospective-review of 2638 medical-records of patients with uveitis in two centers during 17 years. Patients with Vogt-Koyanagi-Harada syndrome were gathered to characterize demographic and clinical data. Results: Twenty-five patients with uveitis were diagnosed with Vogt-Koyanagi-Harada syndrome (0.95%), 78.3% females, mean age of diagnosis 37 years old (SD ±29). Twenty-three patients with complete data were included. Main complaints: blurred vision (87%), headaches (47.8%), tinnitus (26.1%) and hearing impairments (21.7%). Ophthalmic findings: bilateral serous retinal-detachment (67.4%), non-granulomatous uveitis (52.3%). Most of the patients were diagnosed with probable disease (56.5%). Mean duration of follow-up was fourteen months; disease relapse was encountered in 26% of patients despite treatment. Conclusion: Patients in Colombia with Vogt-Koyanagi-Harada had clinical features similar to those reported in other Hispanic populations, except for the non-granulomatous uveitis. This disease may be considered as having variation of clinical manifestations across population groups.

AB - Purpose: To describe the clinical presentation of Vogt-Koyanagi-Harada syndrome in a group of patients in Colombia. Methods: Retrospective-review of 2638 medical-records of patients with uveitis in two centers during 17 years. Patients with Vogt-Koyanagi-Harada syndrome were gathered to characterize demographic and clinical data. Results: Twenty-five patients with uveitis were diagnosed with Vogt-Koyanagi-Harada syndrome (0.95%), 78.3% females, mean age of diagnosis 37 years old (SD ±29). Twenty-three patients with complete data were included. Main complaints: blurred vision (87%), headaches (47.8%), tinnitus (26.1%) and hearing impairments (21.7%). Ophthalmic findings: bilateral serous retinal-detachment (67.4%), non-granulomatous uveitis (52.3%). Most of the patients were diagnosed with probable disease (56.5%). Mean duration of follow-up was fourteen months; disease relapse was encountered in 26% of patients despite treatment. Conclusion: Patients in Colombia with Vogt-Koyanagi-Harada had clinical features similar to those reported in other Hispanic populations, except for the non-granulomatous uveitis. This disease may be considered as having variation of clinical manifestations across population groups.

U2 - 10.1080/09273948.2017.1341536

DO - 10.1080/09273948.2017.1341536

M3 - Research Article

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VL - 26

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JO - Ocular Immunology and Inflammation

JF - Ocular Immunology and Inflammation

IS - 7

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ER -

Vogt–Koyanagi–Harada Syndrome in a Group of Patients in Two Ophthalmology Referral Centers in Bogotá, Colombia: VKH syndrome in Colombia

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