Virus-Induced Anterior Uveitis (VIAU) in Immunocompromised Patients

Ligia Alejandra Delatorre Cifuentes

doi:10.1080/09273948.2018.1483519

Virus-Induced Anterior Uveitis (VIAU) in Immunocompromised Patients

Título traducido de la contribución: Uveítis anterior inducida por virus (VIAU) en pacientes inmunocomprometidos

Ligia Alejandra Delatorre Cifuentes

Producción científica: Contribución a revista › Artículo de revisión › revisión exhaustiva

6 Citas (Scopus)

Resumen

PROPÓSITO:
Describir las características clínicas, el diagnóstico y el tratamiento de VIAU en pacientes inmunocomprometidos.

MÉTODOS:
Se realizó una revisión crítica de la literatura.

RESULTADOS:
El diagnóstico y tratamiento de VIAU en pacientes inmunodeprimidos puede ser un desafío debido a los cursos clínicos atípicos, presentaciones graves y recidivas más frecuentes. Se puede hacer un diagnóstico concluyente mediante análisis de PCR de humor acuoso. El pronóstico visual depende del diagnóstico precoz y el tratamiento oportuno. Se recomiendan exámenes oculares frecuentes en pacientes con VIH con recuentos de CD-4 por debajo de 100 para descartar coinfecciones oculares oportunistas. Es esencial tener en cuenta los posibles efectos secundarios de las intervenciones terapéuticas y considerar la posibilidad de Uveítis de Recuperación Inmune (IRU) en ojos con retinitis viral tratada después del inicio de TARGA.

CONCLUSIONES:
El diagnóstico precoz y el tratamiento de VIAU en pacientes inmunocomprometidos se pueden lograr con alta sospecha, reconociendo las características clínicas y obteniendo muestras para pruebas de diagnóstico molecular a fin de evitar la morbilidad ocular generalmente grave

Título traducido de la contribución	Uveítis anterior inducida por virus (VIAU) en pacientes inmunocomprometidos
Idioma original	Inglés estadounidense
Publicación	Ocular Immunology and Inflammation
Volumen	26
N.º	5
DOI	https://doi.org/10.1080/09273948.2018.1483519
Estado	Publicada - jul. 3 2018

ODS de las Naciones Unidas

Este resultado contribuye a los siguientes Objetivos de Desarrollo Sostenible

ODS 3: Salud y bienestar

Áreas temáticas de ASJC Scopus

General

Acceder al documento

10.1080/09273948.2018.1483519

Citar esto

@article{5d28970bdca4459687d44b8969dd5cb6,

title = "Virus-Induced Anterior Uveitis (VIAU) in Immunocompromised Patients",

abstract = "PURPOSE: To describe the clinical characteristics, diagnosis, and treatment of VIAU in immunocompromised patients. METHODS: A critical review of literature was performed. RESULTS: Diagnosis and treatment of VIAU in immunocompromised patients may be a challenge due to atypical clinical-courses, severe presentations, and more frequent recurrences. A conclusive diagnosis can be made by aqueous-humour PCR-analysis. Visual prognosis depends on early diagnosis and prompt treatment. Frequent ocular examinations are recommended in HIV patients with CD-4-counts below 100 in order to rule out opportunistic ocular coinfections. It is essential to bear in mind the potential side-effects of therapeutic interventions and consider the possibility of Immune Recovery Uveitis (IRU) in eyes with treated viral retinitis after the initiation of HAART. CONCLUSIONS: Early diagnosis and treatment of VIAU in immunocompromised patients can be achieved with high suspicion, recognizing clinical features, and obtaining specimens for molecular diagnostic testing in order to avoid usually severe ocular morbidity.",

author = "\{Delatorre Cifuentes\}, \{Ligia Alejandra\}",

year = "2018",

month = jul,

day = "3",

doi = "10.1080/09273948.2018.1483519",

language = "English (US)",

volume = "26",

journal = "Ocular Immunology and Inflammation",

issn = "0927-3948",

publisher = "Taylor and Francis Ltd.",

number = "5",

}

TY - JOUR

T1 - Virus-Induced Anterior Uveitis (VIAU) in Immunocompromised Patients

AU - Delatorre Cifuentes, Ligia Alejandra

PY - 2018/7/3

Y1 - 2018/7/3

N2 - PURPOSE: To describe the clinical characteristics, diagnosis, and treatment of VIAU in immunocompromised patients. METHODS: A critical review of literature was performed. RESULTS: Diagnosis and treatment of VIAU in immunocompromised patients may be a challenge due to atypical clinical-courses, severe presentations, and more frequent recurrences. A conclusive diagnosis can be made by aqueous-humour PCR-analysis. Visual prognosis depends on early diagnosis and prompt treatment. Frequent ocular examinations are recommended in HIV patients with CD-4-counts below 100 in order to rule out opportunistic ocular coinfections. It is essential to bear in mind the potential side-effects of therapeutic interventions and consider the possibility of Immune Recovery Uveitis (IRU) in eyes with treated viral retinitis after the initiation of HAART. CONCLUSIONS: Early diagnosis and treatment of VIAU in immunocompromised patients can be achieved with high suspicion, recognizing clinical features, and obtaining specimens for molecular diagnostic testing in order to avoid usually severe ocular morbidity.

AB - PURPOSE: To describe the clinical characteristics, diagnosis, and treatment of VIAU in immunocompromised patients. METHODS: A critical review of literature was performed. RESULTS: Diagnosis and treatment of VIAU in immunocompromised patients may be a challenge due to atypical clinical-courses, severe presentations, and more frequent recurrences. A conclusive diagnosis can be made by aqueous-humour PCR-analysis. Visual prognosis depends on early diagnosis and prompt treatment. Frequent ocular examinations are recommended in HIV patients with CD-4-counts below 100 in order to rule out opportunistic ocular coinfections. It is essential to bear in mind the potential side-effects of therapeutic interventions and consider the possibility of Immune Recovery Uveitis (IRU) in eyes with treated viral retinitis after the initiation of HAART. CONCLUSIONS: Early diagnosis and treatment of VIAU in immunocompromised patients can be achieved with high suspicion, recognizing clinical features, and obtaining specimens for molecular diagnostic testing in order to avoid usually severe ocular morbidity.

U2 - 10.1080/09273948.2018.1483519

DO - 10.1080/09273948.2018.1483519

M3 - Review article

C2 - 29969370

SN - 0927-3948

VL - 26

JO - Ocular Immunology and Inflammation

JF - Ocular Immunology and Inflammation

IS - 5

ER -

Virus-Induced Anterior Uveitis (VIAU) in Immunocompromised Patients

Resumen

ODS de las Naciones Unidas

Áreas temáticas de ASJC Scopus

Acceder al documento

Huella

Citar esto