Venezuela's humanitarian crisis, resurgence of vector-borne diseases, and implications for spillover in the region

Maria E Grillet, Juan V Hernández-Villena, Martin S Llewellyn, Alberto E Paniz-Mondolfi, Adriana Tami, Maria F Vincenti-Gonzalez, Marilianna Marquez, Adriana C Mogollon-Mendoza, Carlos E Hernandez-Pereira, Juan D Plaza-Morr, Gabriella Blohm, Mario J Grijalva, Jaime A Costales, Heather M Ferguson, Philipp Schwabl, Luis E Hernandez-Castro, Poppy H L Lamberton, Daniel G Streicker, Daniel T Haydon, Michael A Miles & 28 otros Alvaro Acosta-Serrano, Harry Acquattela, Maria G Basañez, Gustavo Benaim, Luis A Colmenares, Jan E Conn, Raul Espinoza, Hector Freilij, Mary C Graterol-Gil, Peter J Hotez, Hirotomo Kato, John A Lednicky, Clara E Martinez, Santiago Mas-Coma, J Glen Morris, Juan C Navarro, Jose L Ramirez, Marlenes Rodriguez, Julio A Urbina, Leopoldo Villegas, Maikell J Segovia, Hernan J Carrasco, James L Crainey, Sergio L B Luz, Juan D Moreno, Oscar O Noya Gonzalez, Juan David Ramírez, Belkisyolé Alarcón-de Noya

Resultado de la investigación: Contribución a RevistaArtículo de revisión

Resumen

In the past 5-10 years, Venezuela has faced a severe economic crisis, precipitated by political instability and declining oil revenue. Public health provision has been affected particularly. In this Review, we assess the impact of Venezuela's health-care crisis on vector-borne diseases, and the spillover into neighbouring countries. Between 2000 and 2015, Venezuela witnessed a 359% increase in malaria cases, followed by a 71% increase in 2017 (411 586 cases) compared with 2016 (240 613). Neighbouring countries, such as Brazil, have reported an escalating trend of imported malaria cases from Venezuela, from 1538 in 2014 to 3129 in 2017. In Venezuela, active Chagas disease transmission has been reported, with seroprevalence in children (<10 years), estimated to be as high as 12·5% in one community tested (n=64). Dengue incidence increased by more than four times between 1990 and 2016. The estimated incidence of chikungunya during its epidemic peak is 6975 cases per 100 000 people and that of Zika virus is 2057 cases per 100 000 people. The re-emergence of many vector-borne diseases represents a public health crisis in Venezuela and has the possibility of severely undermining regional disease elimination efforts. National, regional, and global authorities must take action to address these worsening epidemics and prevent their expansion beyond Venezuelan borders.

Idioma originalEnglish (US)
PublicaciónThe Lancet Infectious Diseases
DOI
EstadoE-pub ahead of print - feb 21 2019

Citar esto

Grillet, M. E., Hernández-Villena, J. V., Llewellyn, M. S., Paniz-Mondolfi, A. E., Tami, A., Vincenti-Gonzalez, M. F., ... Alarcón-de Noya, B. (2019). Venezuela's humanitarian crisis, resurgence of vector-borne diseases, and implications for spillover in the region. The Lancet Infectious Diseases. https://doi.org/10.1016/S1473-3099(18)30757-6
Grillet, Maria E ; Hernández-Villena, Juan V ; Llewellyn, Martin S ; Paniz-Mondolfi, Alberto E ; Tami, Adriana ; Vincenti-Gonzalez, Maria F ; Marquez, Marilianna ; Mogollon-Mendoza, Adriana C ; Hernandez-Pereira, Carlos E ; Plaza-Morr, Juan D ; Blohm, Gabriella ; Grijalva, Mario J ; Costales, Jaime A ; Ferguson, Heather M ; Schwabl, Philipp ; Hernandez-Castro, Luis E ; Lamberton, Poppy H L ; Streicker, Daniel G ; Haydon, Daniel T ; Miles, Michael A ; Acosta-Serrano, Alvaro ; Acquattela, Harry ; Basañez, Maria G ; Benaim, Gustavo ; Colmenares, Luis A ; Conn, Jan E ; Espinoza, Raul ; Freilij, Hector ; Graterol-Gil, Mary C ; Hotez, Peter J ; Kato, Hirotomo ; Lednicky, John A ; Martinez, Clara E ; Mas-Coma, Santiago ; Morris, J Glen ; Navarro, Juan C ; Ramirez, Jose L ; Rodriguez, Marlenes ; Urbina, Julio A ; Villegas, Leopoldo ; Segovia, Maikell J ; Carrasco, Hernan J ; Crainey, James L ; Luz, Sergio L B ; Moreno, Juan D ; Noya Gonzalez, Oscar O ; Ramírez, Juan David ; Alarcón-de Noya, Belkisyolé. / Venezuela's humanitarian crisis, resurgence of vector-borne diseases, and implications for spillover in the region. En: The Lancet Infectious Diseases. 2019.
@article{221321f86702470baafe22f2aab374d9,
title = "Venezuela's humanitarian crisis, resurgence of vector-borne diseases, and implications for spillover in the region",
abstract = "In the past 5-10 years, Venezuela has faced a severe economic crisis, precipitated by political instability and declining oil revenue. Public health provision has been affected particularly. In this Review, we assess the impact of Venezuela's health-care crisis on vector-borne diseases, and the spillover into neighbouring countries. Between 2000 and 2015, Venezuela witnessed a 359{\%} increase in malaria cases, followed by a 71{\%} increase in 2017 (411 586 cases) compared with 2016 (240 613). Neighbouring countries, such as Brazil, have reported an escalating trend of imported malaria cases from Venezuela, from 1538 in 2014 to 3129 in 2017. In Venezuela, active Chagas disease transmission has been reported, with seroprevalence in children (<10 years), estimated to be as high as 12·5{\%} in one community tested (n=64). Dengue incidence increased by more than four times between 1990 and 2016. The estimated incidence of chikungunya during its epidemic peak is 6975 cases per 100 000 people and that of Zika virus is 2057 cases per 100 000 people. The re-emergence of many vector-borne diseases represents a public health crisis in Venezuela and has the possibility of severely undermining regional disease elimination efforts. National, regional, and global authorities must take action to address these worsening epidemics and prevent their expansion beyond Venezuelan borders.",
author = "Grillet, {Maria E} and Hern{\'a}ndez-Villena, {Juan V} and Llewellyn, {Martin S} and Paniz-Mondolfi, {Alberto E} and Adriana Tami and Vincenti-Gonzalez, {Maria F} and Marilianna Marquez and Mogollon-Mendoza, {Adriana C} and Hernandez-Pereira, {Carlos E} and Plaza-Morr, {Juan D} and Gabriella Blohm and Grijalva, {Mario J} and Costales, {Jaime A} and Ferguson, {Heather M} and Philipp Schwabl and Hernandez-Castro, {Luis E} and Lamberton, {Poppy H L} and Streicker, {Daniel G} and Haydon, {Daniel T} and Miles, {Michael A} and Alvaro Acosta-Serrano and Harry Acquattela and Basa{\~n}ez, {Maria G} and Gustavo Benaim and Colmenares, {Luis A} and Conn, {Jan E} and Raul Espinoza and Hector Freilij and Graterol-Gil, {Mary C} and Hotez, {Peter J} and Hirotomo Kato and Lednicky, {John A} and Martinez, {Clara E} and Santiago Mas-Coma and Morris, {J Glen} and Navarro, {Juan C} and Ramirez, {Jose L} and Marlenes Rodriguez and Urbina, {Julio A} and Leopoldo Villegas and Segovia, {Maikell J} and Carrasco, {Hernan J} and Crainey, {James L} and Luz, {Sergio L B} and Moreno, {Juan D} and {Noya Gonzalez}, {Oscar O} and Ram{\'i}rez, {Juan David} and {Alarc{\'o}n-de Noya}, Belkisyol{\'e}",
note = "Copyright {\circledC} 2019 Elsevier Ltd. All rights reserved.",
year = "2019",
month = "2",
day = "21",
doi = "10.1016/S1473-3099(18)30757-6",
language = "English (US)",
journal = "The Lancet Infectious Diseases",
issn = "1473-3099",
publisher = "Lancet Publishing Group",

}

Grillet, ME, Hernández-Villena, JV, Llewellyn, MS, Paniz-Mondolfi, AE, Tami, A, Vincenti-Gonzalez, MF, Marquez, M, Mogollon-Mendoza, AC, Hernandez-Pereira, CE, Plaza-Morr, JD, Blohm, G, Grijalva, MJ, Costales, JA, Ferguson, HM, Schwabl, P, Hernandez-Castro, LE, Lamberton, PHL, Streicker, DG, Haydon, DT, Miles, MA, Acosta-Serrano, A, Acquattela, H, Basañez, MG, Benaim, G, Colmenares, LA, Conn, JE, Espinoza, R, Freilij, H, Graterol-Gil, MC, Hotez, PJ, Kato, H, Lednicky, JA, Martinez, CE, Mas-Coma, S, Morris, JG, Navarro, JC, Ramirez, JL, Rodriguez, M, Urbina, JA, Villegas, L, Segovia, MJ, Carrasco, HJ, Crainey, JL, Luz, SLB, Moreno, JD, Noya Gonzalez, OO, Ramírez, JD & Alarcón-de Noya, B 2019, 'Venezuela's humanitarian crisis, resurgence of vector-borne diseases, and implications for spillover in the region', The Lancet Infectious Diseases. https://doi.org/10.1016/S1473-3099(18)30757-6

Venezuela's humanitarian crisis, resurgence of vector-borne diseases, and implications for spillover in the region. / Grillet, Maria E; Hernández-Villena, Juan V; Llewellyn, Martin S; Paniz-Mondolfi, Alberto E; Tami, Adriana; Vincenti-Gonzalez, Maria F; Marquez, Marilianna; Mogollon-Mendoza, Adriana C; Hernandez-Pereira, Carlos E; Plaza-Morr, Juan D; Blohm, Gabriella; Grijalva, Mario J; Costales, Jaime A; Ferguson, Heather M; Schwabl, Philipp; Hernandez-Castro, Luis E; Lamberton, Poppy H L; Streicker, Daniel G; Haydon, Daniel T; Miles, Michael A; Acosta-Serrano, Alvaro; Acquattela, Harry; Basañez, Maria G; Benaim, Gustavo; Colmenares, Luis A; Conn, Jan E; Espinoza, Raul; Freilij, Hector; Graterol-Gil, Mary C; Hotez, Peter J; Kato, Hirotomo; Lednicky, John A; Martinez, Clara E; Mas-Coma, Santiago; Morris, J Glen; Navarro, Juan C; Ramirez, Jose L; Rodriguez, Marlenes; Urbina, Julio A; Villegas, Leopoldo; Segovia, Maikell J; Carrasco, Hernan J; Crainey, James L; Luz, Sergio L B; Moreno, Juan D; Noya Gonzalez, Oscar O; Ramírez, Juan David; Alarcón-de Noya, Belkisyolé.

En: The Lancet Infectious Diseases, 21.02.2019.

Resultado de la investigación: Contribución a RevistaArtículo de revisión

TY - JOUR

T1 - Venezuela's humanitarian crisis, resurgence of vector-borne diseases, and implications for spillover in the region

AU - Grillet, Maria E

AU - Hernández-Villena, Juan V

AU - Llewellyn, Martin S

AU - Paniz-Mondolfi, Alberto E

AU - Tami, Adriana

AU - Vincenti-Gonzalez, Maria F

AU - Marquez, Marilianna

AU - Mogollon-Mendoza, Adriana C

AU - Hernandez-Pereira, Carlos E

AU - Plaza-Morr, Juan D

AU - Blohm, Gabriella

AU - Grijalva, Mario J

AU - Costales, Jaime A

AU - Ferguson, Heather M

AU - Schwabl, Philipp

AU - Hernandez-Castro, Luis E

AU - Lamberton, Poppy H L

AU - Streicker, Daniel G

AU - Haydon, Daniel T

AU - Miles, Michael A

AU - Acosta-Serrano, Alvaro

AU - Acquattela, Harry

AU - Basañez, Maria G

AU - Benaim, Gustavo

AU - Colmenares, Luis A

AU - Conn, Jan E

AU - Espinoza, Raul

AU - Freilij, Hector

AU - Graterol-Gil, Mary C

AU - Hotez, Peter J

AU - Kato, Hirotomo

AU - Lednicky, John A

AU - Martinez, Clara E

AU - Mas-Coma, Santiago

AU - Morris, J Glen

AU - Navarro, Juan C

AU - Ramirez, Jose L

AU - Rodriguez, Marlenes

AU - Urbina, Julio A

AU - Villegas, Leopoldo

AU - Segovia, Maikell J

AU - Carrasco, Hernan J

AU - Crainey, James L

AU - Luz, Sergio L B

AU - Moreno, Juan D

AU - Noya Gonzalez, Oscar O

AU - Ramírez, Juan David

AU - Alarcón-de Noya, Belkisyolé

N1 - Copyright © 2019 Elsevier Ltd. All rights reserved.

PY - 2019/2/21

Y1 - 2019/2/21

N2 - In the past 5-10 years, Venezuela has faced a severe economic crisis, precipitated by political instability and declining oil revenue. Public health provision has been affected particularly. In this Review, we assess the impact of Venezuela's health-care crisis on vector-borne diseases, and the spillover into neighbouring countries. Between 2000 and 2015, Venezuela witnessed a 359% increase in malaria cases, followed by a 71% increase in 2017 (411 586 cases) compared with 2016 (240 613). Neighbouring countries, such as Brazil, have reported an escalating trend of imported malaria cases from Venezuela, from 1538 in 2014 to 3129 in 2017. In Venezuela, active Chagas disease transmission has been reported, with seroprevalence in children (<10 years), estimated to be as high as 12·5% in one community tested (n=64). Dengue incidence increased by more than four times between 1990 and 2016. The estimated incidence of chikungunya during its epidemic peak is 6975 cases per 100 000 people and that of Zika virus is 2057 cases per 100 000 people. The re-emergence of many vector-borne diseases represents a public health crisis in Venezuela and has the possibility of severely undermining regional disease elimination efforts. National, regional, and global authorities must take action to address these worsening epidemics and prevent their expansion beyond Venezuelan borders.

AB - In the past 5-10 years, Venezuela has faced a severe economic crisis, precipitated by political instability and declining oil revenue. Public health provision has been affected particularly. In this Review, we assess the impact of Venezuela's health-care crisis on vector-borne diseases, and the spillover into neighbouring countries. Between 2000 and 2015, Venezuela witnessed a 359% increase in malaria cases, followed by a 71% increase in 2017 (411 586 cases) compared with 2016 (240 613). Neighbouring countries, such as Brazil, have reported an escalating trend of imported malaria cases from Venezuela, from 1538 in 2014 to 3129 in 2017. In Venezuela, active Chagas disease transmission has been reported, with seroprevalence in children (<10 years), estimated to be as high as 12·5% in one community tested (n=64). Dengue incidence increased by more than four times between 1990 and 2016. The estimated incidence of chikungunya during its epidemic peak is 6975 cases per 100 000 people and that of Zika virus is 2057 cases per 100 000 people. The re-emergence of many vector-borne diseases represents a public health crisis in Venezuela and has the possibility of severely undermining regional disease elimination efforts. National, regional, and global authorities must take action to address these worsening epidemics and prevent their expansion beyond Venezuelan borders.

U2 - 10.1016/S1473-3099(18)30757-6

DO - 10.1016/S1473-3099(18)30757-6

M3 - Review article

JO - The Lancet Infectious Diseases

JF - The Lancet Infectious Diseases

SN - 1473-3099

ER -