Validation of an enzyme-linked immunosorbent assay that detects Histoplasma capsulatum antigenuria in colombian patients with AIDS for diagnosis and follow-up during therapy

Diego H. Caceres; Christina M. Scheel; Ángela M. Tob́on; Angela Ahlquist Cleveland; Ángela Restrepo; Mary E. Brandt; Tom Chiller; Beatriz L. Gómez

doi:10.1128/CVI.00101-14

Validation of an enzyme-linked immunosorbent assay that detects Histoplasma capsulatum antigenuria in colombian patients with AIDS for diagnosis and follow-up during therapy

Diego H. Caceres
, Christina M. Scheel
, Ángela M. Tob́on
, Angela Ahlquist Cleveland
, Ángela Restrepo
, Mary E. Brandt
, Tom Chiller
, Beatriz L. Gómez

Escuela de Medicina y Ciencias de la Salud

Producción científica: Contribución a revista › Artículo de Investigación › revisión exhaustiva

42 Citas (Scopus)

Resumen

We validated an antigen capture enzyme-linked immunosorbent assay (ELISA) in Colombian persons with AIDS and proven histoplasmosis and evaluated the correlation between antigenuria and clinical improvement during follow-up. The sensitivity of the Histoplasma capsulatum ELISA was 86%, and the overall specificity was 94%. The antigen test successfully monitored the response to therapy.

Idioma original	Inglés estadounidense
Páginas (desde-hasta)	1364-1368
Número de páginas	5
Publicación	Clinical and Vaccine Immunology
Volumen	21
N.º	9
DOI	https://doi.org/10.1128/CVI.00101-14
Estado	Publicada - sep. 2014

ODS de las Naciones Unidas

Este resultado contribuye a los siguientes Objetivos de Desarrollo Sostenible

ODS 3: Salud y bienestar

Áreas temáticas de ASJC Scopus

Inmulogía y alergología
Inmunología
Bioquímica clínica
Microbiología (médica)

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10.1128/CVI.00101-14

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Caceres, D. H., Scheel, C. M., Tob́on, Á. M., Cleveland, A. A., Restrepo, Á., Brandt, M. E., Chiller, T., & Gómez, B. L. (2014). Validation of an enzyme-linked immunosorbent assay that detects Histoplasma capsulatum antigenuria in colombian patients with AIDS for diagnosis and follow-up during therapy. Clinical and Vaccine Immunology, 21(9), 1364-1368. https://doi.org/10.1128/CVI.00101-14

@article{473a12e6d0d846d2bf646b23c1fbca8c,

title = "Validation of an enzyme-linked immunosorbent assay that detects Histoplasma capsulatum antigenuria in colombian patients with AIDS for diagnosis and follow-up during therapy",

abstract = "We validated an antigen capture enzyme-linked immunosorbent assay (ELISA) in Colombian persons with AIDS and proven histoplasmosis and evaluated the correlation between antigenuria and clinical improvement during follow-up. The sensitivity of the Histoplasma capsulatum ELISA was 86\%, and the overall specificity was 94\%. The antigen test successfully monitored the response to therapy.",

author = "Caceres, \{Diego H.\} and Scheel, \{Christina M.\} and To{\'b}on, \{{\'A}ngela M.\} and Cleveland, \{Angela Ahlquist\} and {\'A}ngela Restrepo and Brandt, \{Mary E.\} and Tom Chiller and G{\'o}mez, \{Beatriz L.\}",

year = "2014",

month = sep,

doi = "10.1128/CVI.00101-14",

language = "English (US)",

volume = "21",

pages = "1364--1368",

journal = "Clinical and Vaccine Immunology",

issn = "1556-6811",

publisher = "American Society for Microbiology",

number = "9",

}

Caceres, DH, Scheel, CM, Tob́on, ÁM, Cleveland, AA, Restrepo, Á, Brandt, ME, Chiller, T & Gómez, BL 2014, 'Validation of an enzyme-linked immunosorbent assay that detects Histoplasma capsulatum antigenuria in colombian patients with AIDS for diagnosis and follow-up during therapy', Clinical and Vaccine Immunology, vol. 21, n.º 9, pp. 1364-1368. https://doi.org/10.1128/CVI.00101-14

Validation of an enzyme-linked immunosorbent assay that detects Histoplasma capsulatum antigenuria in colombian patients with AIDS for diagnosis and follow-up during therapy. / Caceres, Diego H.; Scheel, Christina M.; Tob́on, Ángela M. et al.
En: Clinical and Vaccine Immunology, Vol. 21, N.º 9, 09.2014, p. 1364-1368.

Producción científica: Contribución a revista › Artículo de Investigación › revisión exhaustiva

TY - JOUR

T1 - Validation of an enzyme-linked immunosorbent assay that detects Histoplasma capsulatum antigenuria in colombian patients with AIDS for diagnosis and follow-up during therapy

AU - Caceres, Diego H.

AU - Scheel, Christina M.

AU - Tob́on, Ángela M.

AU - Cleveland, Angela Ahlquist

AU - Restrepo, Ángela

AU - Brandt, Mary E.

AU - Chiller, Tom

AU - Gómez, Beatriz L.

PY - 2014/9

Y1 - 2014/9

N2 - We validated an antigen capture enzyme-linked immunosorbent assay (ELISA) in Colombian persons with AIDS and proven histoplasmosis and evaluated the correlation between antigenuria and clinical improvement during follow-up. The sensitivity of the Histoplasma capsulatum ELISA was 86%, and the overall specificity was 94%. The antigen test successfully monitored the response to therapy.

AB - We validated an antigen capture enzyme-linked immunosorbent assay (ELISA) in Colombian persons with AIDS and proven histoplasmosis and evaluated the correlation between antigenuria and clinical improvement during follow-up. The sensitivity of the Histoplasma capsulatum ELISA was 86%, and the overall specificity was 94%. The antigen test successfully monitored the response to therapy.

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U2 - 10.1128/CVI.00101-14

DO - 10.1128/CVI.00101-14

M3 - Research Article

C2 - 25008902

AN - SCOPUS:84940299660

SN - 1556-6811

VL - 21

SP - 1364

EP - 1368

JO - Clinical and Vaccine Immunology

JF - Clinical and Vaccine Immunology

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ER -

Validation of an enzyme-linked immunosorbent assay that detects Histoplasma capsulatum antigenuria in colombian patients with AIDS for diagnosis and follow-up during therapy

Resumen

ODS de las Naciones Unidas

Áreas temáticas de ASJC Scopus

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Huella

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