Validation of an enzyme-linked immunosorbent assay that detects Histoplasma capsulatum antigenuria in colombian patients with AIDS for diagnosis and follow-up during therapy

Diego H. Caceres; Christina M. Scheel; Ángela M. Tob́on; Angela Ahlquist Cleveland; Ángela Restrepo; Mary E. Brandt; Tom Chiller; Beatriz L. Gómez

doi:10.1128/CVI.00101-14

Validation of an enzyme-linked immunosorbent assay that detects Histoplasma capsulatum antigenuria in colombian patients with AIDS for diagnosis and follow-up during therapy

Diego H. Caceres, Christina M. Scheel, Ángela M. Tob́on, Angela Ahlquist Cleveland, Ángela Restrepo, Mary E. Brandt, Tom Chiller, Beatriz L. Gómez

Escuela de Medicina y Ciencias de la Salud

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32 Citas (Scopus)

Resumen

We validated an antigen capture enzyme-linked immunosorbent assay (ELISA) in Colombian persons with AIDS and proven histoplasmosis and evaluated the correlation between antigenuria and clinical improvement during follow-up. The sensitivity of the Histoplasma capsulatum ELISA was 86%, and the overall specificity was 94%. The antigen test successfully monitored the response to therapy.

Idioma original	Inglés estadounidense
Páginas (desde-hasta)	1364-1368
Número de páginas	5
Publicación	Clinical and Vaccine Immunology
Volumen	21
N.º	9
DOI	https://doi.org/10.1128/CVI.00101-14
Estado	Publicada - sep. 2014

Áreas temáticas de ASJC Scopus

Inmulogía y alergología
Inmunología
Bioquímica clínica
Microbiología (médica)

ODS de las Naciones Unidas

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10.1128/CVI.00101-14

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Caceres, D. H., Scheel, C. M., Tob́on, Á. M., Cleveland, A. A., Restrepo, Á., Brandt, M. E., Chiller, T., & Gómez, B. L. (2014). Validation of an enzyme-linked immunosorbent assay that detects Histoplasma capsulatum antigenuria in colombian patients with AIDS for diagnosis and follow-up during therapy. Clinical and Vaccine Immunology, 21(9), 1364-1368. https://doi.org/10.1128/CVI.00101-14

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title = "Validation of an enzyme-linked immunosorbent assay that detects Histoplasma capsulatum antigenuria in colombian patients with AIDS for diagnosis and follow-up during therapy",

abstract = "We validated an antigen capture enzyme-linked immunosorbent assay (ELISA) in Colombian persons with AIDS and proven histoplasmosis and evaluated the correlation between antigenuria and clinical improvement during follow-up. The sensitivity of the Histoplasma capsulatum ELISA was 86%, and the overall specificity was 94%. The antigen test successfully monitored the response to therapy.",

author = "Caceres, {Diego H.} and Scheel, {Christina M.} and To{\'b}on, {{\'A}ngela M.} and Cleveland, {Angela Ahlquist} and {\'A}ngela Restrepo and Brandt, {Mary E.} and Tom Chiller and G{\'o}mez, {Beatriz L.}",

year = "2014",

month = sep,

doi = "10.1128/CVI.00101-14",

language = "English (US)",

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Caceres, DH, Scheel, CM, Tob́on, ÁM, Cleveland, AA, Restrepo, Á, Brandt, ME, Chiller, T & Gómez, BL 2014, 'Validation of an enzyme-linked immunosorbent assay that detects Histoplasma capsulatum antigenuria in colombian patients with AIDS for diagnosis and follow-up during therapy', Clinical and Vaccine Immunology, vol. 21, n.º 9, pp. 1364-1368. https://doi.org/10.1128/CVI.00101-14

Validation of an enzyme-linked immunosorbent assay that detects Histoplasma capsulatum antigenuria in colombian patients with AIDS for diagnosis and follow-up during therapy. / Caceres, Diego H.; Scheel, Christina M.; Tob́on, Ángela M. et al.
En: Clinical and Vaccine Immunology, Vol. 21, N.º 9, 09.2014, p. 1364-1368.

Producción científica: Contribución a una revista › Artículo › revisión exhaustiva

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AU - Caceres, Diego H.

AU - Scheel, Christina M.

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AU - Cleveland, Angela Ahlquist

AU - Restrepo, Ángela

AU - Brandt, Mary E.

AU - Chiller, Tom

AU - Gómez, Beatriz L.

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AB - We validated an antigen capture enzyme-linked immunosorbent assay (ELISA) in Colombian persons with AIDS and proven histoplasmosis and evaluated the correlation between antigenuria and clinical improvement during follow-up. The sensitivity of the Histoplasma capsulatum ELISA was 86%, and the overall specificity was 94%. The antigen test successfully monitored the response to therapy.

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Validation of an enzyme-linked immunosorbent assay that detects Histoplasma capsulatum antigenuria in colombian patients with AIDS for diagnosis and follow-up during therapy

Resumen

Áreas temáticas de ASJC Scopus

ODS de las Naciones Unidas

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