Usefulness of patients-reported outcomes in rheumatoid arthritis focus group

Jenny Amaya-Amaya, Diana Botello-Corzo, Omar Javier Calixto, Rolando Calderón-Rojas, Aura-Maria Domínguez, Paola Cruz-Tapias, Gladis Montoya-Ortiz, Ruben-Dario Mantilla, Juan-Manuel Anaya, Adriana Rojas-Villarraga

Resultado de la investigación: Contribución a RevistaArtículo

Resumen

Objective. Patient-reported outcomes (PROs) have become an essential part of the assessment of patients with rheumatoid arthritis (RA). We aimed to evaluate the agreement and correlation between PROs and the physician's measurements. Methods. This was a cross-sectional analytical study in which 135 patients with RA were clinically evaluated during two different sessions of focus group interviews. Rheumatologist recorded 28 swollen (SJCs) and tender joint counts (TJCs). The patients filled out the PROs instruments (MDHAQ, RADAI, RAPID3, 4, and 5 and self-report articular index (SAI) diagram for pain and joint swelling). DAS28 was calculated (C-reactive protein). An adjusted multiple lineal regression model was done (DAS28 as dependent variable). Results. Highly significant agreements were found between SJC and TJC registered by the physician and patient. There was moderate correlation between DAS28 with patient SJC (r = 0.52), patient TJC (r = 0.55), RADAI (r = 0.56), RAPID3 (r = 0.52), RAPID4 (r = 0.56), RAPID5 (r = 0.66), and VAS-Global (r = 0.51). Likewise, we found moderate to high correlations between CDAI and SDAI with all variable measurements done by the patients. The resulting predictive equation was DAS28(CRP) = 2.02 + 0.037 × RAPID4 + 0.042× patient SJC. Conclusion. PROs applied in focus groups interview are a useful tool for managing patients with RA regardless of gender, educational level, and duration of disease.

Idioma originalEnglish (US)
Número de páginas13
PublicaciónArthritis
Volumen2012
DOI
EstadoPublished - 2012

Huella dactilar

Focus Groups
Rheumatoid Arthritis
Joints
Interviews
Physicians
Patient Reported Outcome Measures
Arthralgia
C-Reactive Protein
Self Report
Cross-Sectional Studies

Citar esto

Amaya-Amaya, J., Botello-Corzo, D., Calixto, O. J., Calderón-Rojas, R., Domínguez, A-M., Cruz-Tapias, P., ... Rojas-Villarraga, A. (2012). Usefulness of patients-reported outcomes in rheumatoid arthritis focus group. Arthritis, 2012. https://doi.org/10.1155/2012/935187
Amaya-Amaya, Jenny ; Botello-Corzo, Diana ; Calixto, Omar Javier ; Calderón-Rojas, Rolando ; Domínguez, Aura-Maria ; Cruz-Tapias, Paola ; Montoya-Ortiz, Gladis ; Mantilla, Ruben-Dario ; Anaya, Juan-Manuel ; Rojas-Villarraga, Adriana. / Usefulness of patients-reported outcomes in rheumatoid arthritis focus group. En: Arthritis. 2012 ; Vol. 2012.
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title = "Usefulness of patients-reported outcomes in rheumatoid arthritis focus group",
abstract = "Objective. Patient-reported outcomes (PROs) have become an essential part of the assessment of patients with rheumatoid arthritis (RA). We aimed to evaluate the agreement and correlation between PROs and the physician's measurements. Methods. This was a cross-sectional analytical study in which 135 patients with RA were clinically evaluated during two different sessions of focus group interviews. Rheumatologist recorded 28 swollen (SJCs) and tender joint counts (TJCs). The patients filled out the PROs instruments (MDHAQ, RADAI, RAPID3, 4, and 5 and self-report articular index (SAI) diagram for pain and joint swelling). DAS28 was calculated (C-reactive protein). An adjusted multiple lineal regression model was done (DAS28 as dependent variable). Results. Highly significant agreements were found between SJC and TJC registered by the physician and patient. There was moderate correlation between DAS28 with patient SJC (r = 0.52), patient TJC (r = 0.55), RADAI (r = 0.56), RAPID3 (r = 0.52), RAPID4 (r = 0.56), RAPID5 (r = 0.66), and VAS-Global (r = 0.51). Likewise, we found moderate to high correlations between CDAI and SDAI with all variable measurements done by the patients. The resulting predictive equation was DAS28(CRP) = 2.02 + 0.037 × RAPID4 + 0.042× patient SJC. Conclusion. PROs applied in focus groups interview are a useful tool for managing patients with RA regardless of gender, educational level, and duration of disease.",
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doi = "10.1155/2012/935187",
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journal = "Arthritis",
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Amaya-Amaya, J, Botello-Corzo, D, Calixto, OJ, Calderón-Rojas, R, Domínguez, A-M, Cruz-Tapias, P, Montoya-Ortiz, G, Mantilla, R-D, Anaya, J-M & Rojas-Villarraga, A 2012, 'Usefulness of patients-reported outcomes in rheumatoid arthritis focus group', Arthritis, vol. 2012. https://doi.org/10.1155/2012/935187

Usefulness of patients-reported outcomes in rheumatoid arthritis focus group. / Amaya-Amaya, Jenny; Botello-Corzo, Diana; Calixto, Omar Javier; Calderón-Rojas, Rolando; Domínguez, Aura-Maria; Cruz-Tapias, Paola; Montoya-Ortiz, Gladis; Mantilla, Ruben-Dario; Anaya, Juan-Manuel; Rojas-Villarraga, Adriana.

En: Arthritis, Vol. 2012, 2012.

Resultado de la investigación: Contribución a RevistaArtículo

TY - JOUR

T1 - Usefulness of patients-reported outcomes in rheumatoid arthritis focus group

AU - Amaya-Amaya, Jenny

AU - Botello-Corzo, Diana

AU - Calixto, Omar Javier

AU - Calderón-Rojas, Rolando

AU - Domínguez, Aura-Maria

AU - Cruz-Tapias, Paola

AU - Montoya-Ortiz, Gladis

AU - Mantilla, Ruben-Dario

AU - Anaya, Juan-Manuel

AU - Rojas-Villarraga, Adriana

PY - 2012

Y1 - 2012

N2 - Objective. Patient-reported outcomes (PROs) have become an essential part of the assessment of patients with rheumatoid arthritis (RA). We aimed to evaluate the agreement and correlation between PROs and the physician's measurements. Methods. This was a cross-sectional analytical study in which 135 patients with RA were clinically evaluated during two different sessions of focus group interviews. Rheumatologist recorded 28 swollen (SJCs) and tender joint counts (TJCs). The patients filled out the PROs instruments (MDHAQ, RADAI, RAPID3, 4, and 5 and self-report articular index (SAI) diagram for pain and joint swelling). DAS28 was calculated (C-reactive protein). An adjusted multiple lineal regression model was done (DAS28 as dependent variable). Results. Highly significant agreements were found between SJC and TJC registered by the physician and patient. There was moderate correlation between DAS28 with patient SJC (r = 0.52), patient TJC (r = 0.55), RADAI (r = 0.56), RAPID3 (r = 0.52), RAPID4 (r = 0.56), RAPID5 (r = 0.66), and VAS-Global (r = 0.51). Likewise, we found moderate to high correlations between CDAI and SDAI with all variable measurements done by the patients. The resulting predictive equation was DAS28(CRP) = 2.02 + 0.037 × RAPID4 + 0.042× patient SJC. Conclusion. PROs applied in focus groups interview are a useful tool for managing patients with RA regardless of gender, educational level, and duration of disease.

AB - Objective. Patient-reported outcomes (PROs) have become an essential part of the assessment of patients with rheumatoid arthritis (RA). We aimed to evaluate the agreement and correlation between PROs and the physician's measurements. Methods. This was a cross-sectional analytical study in which 135 patients with RA were clinically evaluated during two different sessions of focus group interviews. Rheumatologist recorded 28 swollen (SJCs) and tender joint counts (TJCs). The patients filled out the PROs instruments (MDHAQ, RADAI, RAPID3, 4, and 5 and self-report articular index (SAI) diagram for pain and joint swelling). DAS28 was calculated (C-reactive protein). An adjusted multiple lineal regression model was done (DAS28 as dependent variable). Results. Highly significant agreements were found between SJC and TJC registered by the physician and patient. There was moderate correlation between DAS28 with patient SJC (r = 0.52), patient TJC (r = 0.55), RADAI (r = 0.56), RAPID3 (r = 0.52), RAPID4 (r = 0.56), RAPID5 (r = 0.66), and VAS-Global (r = 0.51). Likewise, we found moderate to high correlations between CDAI and SDAI with all variable measurements done by the patients. The resulting predictive equation was DAS28(CRP) = 2.02 + 0.037 × RAPID4 + 0.042× patient SJC. Conclusion. PROs applied in focus groups interview are a useful tool for managing patients with RA regardless of gender, educational level, and duration of disease.

U2 - 10.1155/2012/935187

DO - 10.1155/2012/935187

M3 - Article

C2 - 23097701

VL - 2012

JO - Arthritis

JF - Arthritis

SN - 2090-1984

ER -

Amaya-Amaya J, Botello-Corzo D, Calixto OJ, Calderón-Rojas R, Domínguez A-M, Cruz-Tapias P y otros. Usefulness of patients-reported outcomes in rheumatoid arthritis focus group. Arthritis. 2012;2012. https://doi.org/10.1155/2012/935187