Use of subcutaneous ivermectin in hyperinfection syndrome by Strongyloides stercoralis. A case report / Uso de ivermectina subcutánea en síndrome de hiperinfección por Strongyloides stercoralis. Reporte un caso

Diana Carolina Hennessey, Oscar Andrés Ballesteros, Diego Javier Merchán, Freddy Orlando Guevara, Diego Fernando Severiche

Resultado de la investigación: Contribución a una revistaArtículorevisión exhaustiva

Resumen

Strongyloidiasis is a disease caused by the nematode Strongyloides stercoralis that is endemic in rural regions in tropical and subtropical countries. Immunosuppressed patients have an increased risk of infection by this parasitic and are at risk of developing a hyperinfection syndrome which carries a higher risk of death. However, in Colombia and the world there is no parenteral presentation of ivermectin for the use in humans, which is an important problem in patients who have compromised enteral absorption, as in the case of patients with intestinal obstructions. We present the first case of hyperinfection syndrome by Strongyloides stercoralis in Colombia treated with subcutaneous ivermectin in order to encourage pharmacokinetic and pharmacodynamic studies to establish this route of administration in the future as an alternative to those patients who have a high risk of therapeutic failure with the oral route. © 2019, Instituto Nacional de Salud.
Título traducido de la contribuciónUse of subcutaneous ivermectin in hyperinfection syndrome by Strongyloides stercoralis. A case report
Idioma originalInglés
Número de artículo6098
PublicaciónBiomedica
Volumen40
N.º2
EstadoPublicada - jun 15 2020

All Science Journal Classification (ASJC) codes

  • Bioquímica, genética y biología molecular (todo)

Concepts

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Huella Profundice en los temas de investigación de 'Use of subcutaneous ivermectin in hyperinfection syndrome by Strongyloides stercoralis. A case report / Uso de ivermectina subcutánea en síndrome de hiperinfección por Strongyloides stercoralis. Reporte un caso'. En conjunto forman una huella única.

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