High-Resolution Molecular Typing of Trypanosoma cruzi in 2 Large Outbreaks of Acute Chagas Disease in Colombia

Título traducido de la contribución: Tipificación molecular de alta resolución de Trypanosoma cruzi en 2 grandes brotes de la enfermedad aguda de Chagas en Colombia

Carolina Hernández, Mauricio Javier Vera, Zulma Cucunubá, Carolina Flórez, Omar Cantillo, Luz Stella Buitrago, Marina Stella González, Susanne Ardila, Liliana Zuleta Dueñas, Rubn Tovar, Luis Fernando Forero, Juan David Ramírez

Resultado de la investigación: Contribución a RevistaArtículo

10 Citas (Scopus)

Resumen

La transmisión oral de Trypanosoma cruzi ha ganado relevancia por su asociación con altas tasas de morbilidad y mortalidad. Esta vía de transmisión es la responsable de mantener la infección del parásito en los ciclos selváticos, y los casos humanos se han asociado principalmente con el consumo de alimentos contaminados con heces de triatomina o secreciones de didelphid. Varios cambios ecológicos permiten la intrusión de reservorios selváticos y triatomines en los ambientes domésticos con la consiguiente contaminación de los alimentos. Aquí se utilizaron herramientas moleculares de alta resolución para detectar y genotipo T. cruzi en humanos, reservorios e insectos vectores en 2 brotes agudos de presunta transmisión oral en el este de Colombia.
Idioma originalEnglish (US)
Páginas (desde-hasta)1252-1255
Número de páginas3
PublicaciónJournal of Infectious Diseases
Volumen214
N.º8
DOI
EstadoPublished - oct 15 2016

Huella dactilar

Molecular Typing
Colombia
Chagas Disease
Trypanosoma cruzi
Acute Disease
Disease Outbreaks
Insect Vectors
Food Contamination
Parasitic Diseases
Feces
Genotype
Morbidity
Food

Citar esto

Hernández, Carolina ; Vera, Mauricio Javier ; Cucunubá, Zulma ; Flórez, Carolina ; Cantillo, Omar ; Buitrago, Luz Stella ; González, Marina Stella ; Ardila, Susanne ; Dueñas, Liliana Zuleta ; Tovar, Rubn ; Forero, Luis Fernando ; Ramírez, Juan David. / High-Resolution Molecular Typing of Trypanosoma cruzi in 2 Large Outbreaks of Acute Chagas Disease in Colombia. En: Journal of Infectious Diseases. 2016 ; Vol. 214, N.º 8. pp. 1252-1255.
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abstract = "{\circledC} 2016 The Author.Oral transmission of Trypanosoma cruzi has gained relevance because of its association with high morbidity and lethality rates. This transmission route is responsible for maintaining the infection of the parasite in sylvatic cycles, and human cases have been associated mainly with the consumption of food contaminated with triatomine feces or didelphid secretions. Several ecological changes allow the intrusion of sylvatic reservoirs and triatomines to the domestic environments with subsequent food contamination. Here, high-resolution molecular tools were used to detect and genotype T. cruzi across humans, reservoirs, and insect vectors in 2 acute outbreaks of presumptive oral transmission in eastern Colombia.",
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Hernández, C, Vera, MJ, Cucunubá, Z, Flórez, C, Cantillo, O, Buitrago, LS, González, MS, Ardila, S, Dueñas, LZ, Tovar, R, Forero, LF & Ramírez, JD 2016, 'High-Resolution Molecular Typing of Trypanosoma cruzi in 2 Large Outbreaks of Acute Chagas Disease in Colombia', Journal of Infectious Diseases, vol. 214, n.º 8, pp. 1252-1255. https://doi.org/10.1093/infdis/jiw360, https://doi.org/10.1093/infdis/jiw360

High-Resolution Molecular Typing of Trypanosoma cruzi in 2 Large Outbreaks of Acute Chagas Disease in Colombia. / Hernández, Carolina; Vera, Mauricio Javier; Cucunubá, Zulma; Flórez, Carolina; Cantillo, Omar; Buitrago, Luz Stella; González, Marina Stella; Ardila, Susanne; Dueñas, Liliana Zuleta; Tovar, Rubn; Forero, Luis Fernando; Ramírez, Juan David.

En: Journal of Infectious Diseases, Vol. 214, N.º 8, 15.10.2016, p. 1252-1255.

Resultado de la investigación: Contribución a RevistaArtículo

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AU - Cantillo, Omar

AU - Buitrago, Luz Stella

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AU - Dueñas, Liliana Zuleta

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AB - © 2016 The Author.Oral transmission of Trypanosoma cruzi has gained relevance because of its association with high morbidity and lethality rates. This transmission route is responsible for maintaining the infection of the parasite in sylvatic cycles, and human cases have been associated mainly with the consumption of food contaminated with triatomine feces or didelphid secretions. Several ecological changes allow the intrusion of sylvatic reservoirs and triatomines to the domestic environments with subsequent food contamination. Here, high-resolution molecular tools were used to detect and genotype T. cruzi across humans, reservoirs, and insect vectors in 2 acute outbreaks of presumptive oral transmission in eastern Colombia.

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