The combined association of adherence to Mediterranean diet, muscular and cardiorespiratory fitness on low-grade inflammation in adolescents

a pooled analysis

César Agostinis-Sobrinho, Robinson Ramírez-Vélez, Antonio García-Hermoso, Rafaela Rosário, Carla Moreira, Luís Lopes, Arvydas Martinkenas, Jorge Mota, Rute Santos

Resultado de la investigación: Contribución a RevistaArtículo

1 Cita (Scopus)

Resumen

PROPÓSITO:
La inflamación de bajo grado conduce a varios trastornos metabólicos, y la adherencia a una dieta mediterránea (MedDiet), el acondicionamiento cardiorrespiratorio (CRF) y el acondicionamiento muscular (MF) se han considerado marcadores importantes de salud metabólica en la juventud. Se investigó la asociación combinada de la adherencia a la dieta mediterránea y el estado físico muscular y cardiorrespiratorio con la proteína C reactiva de alta sensibilidad (PCR-ps) en adolescentes.

MÉTODOS:
Este es un análisis transversal con 1462 adolescentes (625 niñas) de 9 a 18 años de Colombia y Portugal. MedDiet fue evaluado por el cuestionario de Kidmed. La prueba de funcionamiento del transbordador se utilizó para evaluar el CRF. La MF se evaluó mediante las pruebas de salto de longitud en pie y de empuñadura. Se utilizaron ensayos de alta sensibilidad para obtener el nivel de PCR de alta sensibilidad.

RESULTADOS:
La regresión logística muestra que los sujetos con una baja adherencia a MedDiet y LowMF/LowCRF tuvieron probabilidades similares (OR = 2,3; IC del 95%: 1,2 a 4,0) que aquellos con una adherencia óptima a MedDiet y LowMF/LowCRF (OR = 2,3; IC del 95%: 1,2 a 5,0) de expresar un alto perfil inflamatorio en comparación con aquellos con una adherencia óptima a MedDiet y HighMF/HighCRF. Además, ANCOVA mostró que los sujetos clasificados como de alta adherencia a MedDiet y HighMF/HighCRF tuvieron, en promedio, los niveles más bajos de PCR-as (F(7,1454) = 2.051 p = 0.04).

CONCLUSIÓN:
La combinación de niveles óptimos de CRF y MF y la adherencia a MedDiet se asocia con una menor PCR-ps. Sin embargo, la alta MF y CRF parece contrarrestar el efecto perjudicial de tener una baja adherencia a MedDiet en los niveles de hs-CRP.
Idioma originalEnglish (US)
PublicaciónEuropean Journal of Nutrition
DOI
EstadoAccepted/In press - ene 1 2018

All Science Journal Classification (ASJC) codes

  • Medicine (miscellaneous)
  • Nutrition and Dietetics

Citar esto

Agostinis-Sobrinho, César ; Ramírez-Vélez, Robinson ; García-Hermoso, Antonio ; Rosário, Rafaela ; Moreira, Carla ; Lopes, Luís ; Martinkenas, Arvydas ; Mota, Jorge ; Santos, Rute. / The combined association of adherence to Mediterranean diet, muscular and cardiorespiratory fitness on low-grade inflammation in adolescents : a pooled analysis. En: European Journal of Nutrition. 2018.
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title = "The combined association of adherence to Mediterranean diet, muscular and cardiorespiratory fitness on low-grade inflammation in adolescents: a pooled analysis",
abstract = "Purpose: Low-grade inflammation leads to several metabolic disorders, and adherence to a Mediterranean diet (MedDiet), cardiorespiratory fitness (CRF), and muscular fitness (MF) has been considered important markers of metabolic healthy in youth. We investigated the combined association of adherence to Mediterranean diet, and muscular and cardiorespiratory fitness on high-sensitivity C-reactive protein (hs-CRP) in adolescents. Methods: This is a cross-sectional analysis with 1462 adolescents (625 girls) aged 9–18 years from Colombia and Portugal. MedDiet was assessed by Kidmed questionnaire. Shuttle run test was used to assess CRF. MF was assessed by the standing long-jump and handgrip tests. High-sensitivity assays were used to obtain the hs-CRP level. Results: Logistic regression shows that subjects with a low adherence to MedDiet and LowMF/LowCRF had a similar odds (OR = 2.3; 95{\%} CI 1.2–4.0) as those with an optimal adherence to MedDiet and LowMF/LowCRF (OR = 2.3; 95{\%} CI 1.2–5.0) of expressing high inflammatory profile when compared to those with an optimal adherence to MedDiet and HighMF/HighCRF. In addition, ANCOVA showed that subjects classified as high adherence to MedDiet and HighMF/HighCRF had, on average, the lowest levels of hs-CRP (F(7,1454) = 2.051 p = 0.04). Conclusion: The combination of optimal levels of CRF and MF and adherence to MedDiet is associated with lower hs-CRP. However, high MF and CRF seems to counteract the deleterious effect of having a low adherence to the MedDiet on hs-CRP levels.",
author = "C{\'e}sar Agostinis-Sobrinho and Robinson Ram{\'i}rez-V{\'e}lez and Antonio Garc{\'i}a-Hermoso and Rafaela Ros{\'a}rio and Carla Moreira and Lu{\'i}s Lopes and Arvydas Martinkenas and Jorge Mota and Rute Santos",
year = "2018",
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doi = "10.1007/s00394-018-1812-0",
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The combined association of adherence to Mediterranean diet, muscular and cardiorespiratory fitness on low-grade inflammation in adolescents : a pooled analysis. / Agostinis-Sobrinho, César; Ramírez-Vélez, Robinson; García-Hermoso, Antonio; Rosário, Rafaela; Moreira, Carla; Lopes, Luís; Martinkenas, Arvydas; Mota, Jorge; Santos, Rute.

En: European Journal of Nutrition, 01.01.2018.

Resultado de la investigación: Contribución a RevistaArtículo

TY - JOUR

T1 - The combined association of adherence to Mediterranean diet, muscular and cardiorespiratory fitness on low-grade inflammation in adolescents

T2 - a pooled analysis

AU - Agostinis-Sobrinho, César

AU - Ramírez-Vélez, Robinson

AU - García-Hermoso, Antonio

AU - Rosário, Rafaela

AU - Moreira, Carla

AU - Lopes, Luís

AU - Martinkenas, Arvydas

AU - Mota, Jorge

AU - Santos, Rute

PY - 2018/1/1

Y1 - 2018/1/1

N2 - Purpose: Low-grade inflammation leads to several metabolic disorders, and adherence to a Mediterranean diet (MedDiet), cardiorespiratory fitness (CRF), and muscular fitness (MF) has been considered important markers of metabolic healthy in youth. We investigated the combined association of adherence to Mediterranean diet, and muscular and cardiorespiratory fitness on high-sensitivity C-reactive protein (hs-CRP) in adolescents. Methods: This is a cross-sectional analysis with 1462 adolescents (625 girls) aged 9–18 years from Colombia and Portugal. MedDiet was assessed by Kidmed questionnaire. Shuttle run test was used to assess CRF. MF was assessed by the standing long-jump and handgrip tests. High-sensitivity assays were used to obtain the hs-CRP level. Results: Logistic regression shows that subjects with a low adherence to MedDiet and LowMF/LowCRF had a similar odds (OR = 2.3; 95% CI 1.2–4.0) as those with an optimal adherence to MedDiet and LowMF/LowCRF (OR = 2.3; 95% CI 1.2–5.0) of expressing high inflammatory profile when compared to those with an optimal adherence to MedDiet and HighMF/HighCRF. In addition, ANCOVA showed that subjects classified as high adherence to MedDiet and HighMF/HighCRF had, on average, the lowest levels of hs-CRP (F(7,1454) = 2.051 p = 0.04). Conclusion: The combination of optimal levels of CRF and MF and adherence to MedDiet is associated with lower hs-CRP. However, high MF and CRF seems to counteract the deleterious effect of having a low adherence to the MedDiet on hs-CRP levels.

AB - Purpose: Low-grade inflammation leads to several metabolic disorders, and adherence to a Mediterranean diet (MedDiet), cardiorespiratory fitness (CRF), and muscular fitness (MF) has been considered important markers of metabolic healthy in youth. We investigated the combined association of adherence to Mediterranean diet, and muscular and cardiorespiratory fitness on high-sensitivity C-reactive protein (hs-CRP) in adolescents. Methods: This is a cross-sectional analysis with 1462 adolescents (625 girls) aged 9–18 years from Colombia and Portugal. MedDiet was assessed by Kidmed questionnaire. Shuttle run test was used to assess CRF. MF was assessed by the standing long-jump and handgrip tests. High-sensitivity assays were used to obtain the hs-CRP level. Results: Logistic regression shows that subjects with a low adherence to MedDiet and LowMF/LowCRF had a similar odds (OR = 2.3; 95% CI 1.2–4.0) as those with an optimal adherence to MedDiet and LowMF/LowCRF (OR = 2.3; 95% CI 1.2–5.0) of expressing high inflammatory profile when compared to those with an optimal adherence to MedDiet and HighMF/HighCRF. In addition, ANCOVA showed that subjects classified as high adherence to MedDiet and HighMF/HighCRF had, on average, the lowest levels of hs-CRP (F(7,1454) = 2.051 p = 0.04). Conclusion: The combination of optimal levels of CRF and MF and adherence to MedDiet is associated with lower hs-CRP. However, high MF and CRF seems to counteract the deleterious effect of having a low adherence to the MedDiet on hs-CRP levels.

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U2 - 10.1007/s00394-018-1812-0

DO - 10.1007/s00394-018-1812-0

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JO - European Journal of Nutrition

JF - European Journal of Nutrition

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