Temporal variation of Trypanosoma cruzi discrete typing units in asymptomatic Chagas disease patients

Laura V. Sánchez; Diana C. Bautista; Andrés F. Corredor; Victor M. Herrera; Luz X. Martinez; Juan Carlos Villar; Juan David Ramírez

doi:10.1016/j.micinf.2013.06.008

Temporal variation of Trypanosoma cruzi discrete typing units in asymptomatic Chagas disease patients

Laura V. Sánchez, Diana C. Bautista, Andrés F. Corredor, Victor M. Herrera, Luz X. Martinez, Juan Carlos Villar, Juan David Ramírez

Producción científica: Contribución a una revista › Artículo › revisión exhaustiva

8 Citas (Scopus)

Resumen

Chagas disease caused by Trypanosoma cruzi is a public health problem in Latin America. This parasite displays a high genetic diversity evidenced in six Discrete Typing Units (DTUs) namely TcI-TcVI. The aim of this study was to observe the temporal variation of the DTUs in asymptomatic patients at three different times (10 days interval). The results showed that intermittence is the rule in the bloodstream of Chagas disease patients. The patients showed different detectable DTUs with short time intervals, which favors the clonal histiotropic model and the multiclonality structure of this parasite.

Idioma original	Inglés estadounidense
Páginas (desde-hasta)	745-748
Número de páginas	4
Publicación	Microbes and Infection
Volumen	15
N.º	10-11
DOI	https://doi.org/10.1016/j.micinf.2013.06.008
Estado	Publicada - sep. 2013
Publicado de forma externa	Sí

Áreas temáticas de ASJC Scopus

Microbiología
Inmunología
Enfermedades infecciosas

ODS de las Naciones Unidas

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title = "Temporal variation of Trypanosoma cruzi discrete typing units in asymptomatic Chagas disease patients",

abstract = "Chagas disease caused by Trypanosoma cruzi is a public health problem in Latin America. This parasite displays a high genetic diversity evidenced in six Discrete Typing Units (DTUs) namely TcI-TcVI. The aim of this study was to observe the temporal variation of the DTUs in asymptomatic patients at three different times (10 days interval). The results showed that intermittence is the rule in the bloodstream of Chagas disease patients. The patients showed different detectable DTUs with short time intervals, which favors the clonal histiotropic model and the multiclonality structure of this parasite.",

author = "S{\'a}nchez, {Laura V.} and Bautista, {Diana C.} and Corredor, {Andr{\'e}s F.} and Herrera, {Victor M.} and Martinez, {Luz X.} and Villar, {Juan Carlos} and Ram{\'i}rez, {Juan David}",

year = "2013",

month = sep,

doi = "10.1016/j.micinf.2013.06.008",

language = "English (US)",

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journal = "Microbes and Infection",

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T1 - Temporal variation of Trypanosoma cruzi discrete typing units in asymptomatic Chagas disease patients

AU - Sánchez, Laura V.

AU - Bautista, Diana C.

AU - Corredor, Andrés F.

AU - Herrera, Victor M.

AU - Martinez, Luz X.

AU - Villar, Juan Carlos

AU - Ramírez, Juan David

PY - 2013/9

Y1 - 2013/9

N2 - Chagas disease caused by Trypanosoma cruzi is a public health problem in Latin America. This parasite displays a high genetic diversity evidenced in six Discrete Typing Units (DTUs) namely TcI-TcVI. The aim of this study was to observe the temporal variation of the DTUs in asymptomatic patients at three different times (10 days interval). The results showed that intermittence is the rule in the bloodstream of Chagas disease patients. The patients showed different detectable DTUs with short time intervals, which favors the clonal histiotropic model and the multiclonality structure of this parasite.

AB - Chagas disease caused by Trypanosoma cruzi is a public health problem in Latin America. This parasite displays a high genetic diversity evidenced in six Discrete Typing Units (DTUs) namely TcI-TcVI. The aim of this study was to observe the temporal variation of the DTUs in asymptomatic patients at three different times (10 days interval). The results showed that intermittence is the rule in the bloodstream of Chagas disease patients. The patients showed different detectable DTUs with short time intervals, which favors the clonal histiotropic model and the multiclonality structure of this parasite.

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AN - SCOPUS:84884160270

SN - 1286-4579

VL - 15

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JO - Microbes and Infection

JF - Microbes and Infection

IS - 10-11

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Temporal variation of Trypanosoma cruzi discrete typing units in asymptomatic Chagas disease patients

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