Sjögren's syndrome at the crossroad of polyautoimmunity

Manuel J. Amador-Patarroyo, Juan Guillermo Arbelaez, Ruben D. Mantilla, Alberto Rodriguez-Rodriguez, Jorge Cárdenas-Roldán, Ricardo Pineda-Tamayo, Mayra R. Guarin, Liliana Lopez Kleine, Adriana Rojas-Villarraga, Juan Manuel Anaya

Resultado de la investigación: Contribución a RevistaArtículo

42 Citas (Scopus)

Resumen

The coexistence of autoimmune diseases (i.e., polyautoimmunity) in Sjögren's syndrome (SS) was investigated in a cross-sectional study involving 410 patients. Logistic regression analysis and the Rogers and Tanimoto index were used to evaluate risk factors and clustering, respectively. There were 134 (32.6%) patients with polyautoimmunity. The most frequent and closer coexistent diseases were autoimmune thyroid disease (21.5%), rheumatoid arthritis (8.3%), systemic lupus erythematosus (7.6%), and inflammatory bowel disease (0.7%) which together constituted a cluster group. There were 35 (8.5%) patients with multiple autoimmune syndrome. Besides disease duration, a history of habitual smoking and spontaneous abortion were found to be risk factors for the developing of polyautoimmunity. This study discloses a high prevalence of polyautoimmunity in SS, its associated risk factors and the grouping pattern of such a condition. These results may serve to define plausible approaches to study the common mechanisms of autoimmune diseases. © 2012 Elsevier Ltd.
Idioma originalEnglish (US)
Páginas (desde-hasta)199-205
Número de páginas7
PublicaciónJournal of Autoimmunity
DOI
EstadoPublished - sep 1 2012

Huella dactilar

Sjogren's Syndrome
Autoimmune Diseases
Habitual Abortion
Thyroid Diseases
Spontaneous Abortion
Inflammatory Bowel Diseases
Systemic Lupus Erythematosus
Cluster Analysis
Rheumatoid Arthritis
Cross-Sectional Studies
Logistic Models
Smoking
Regression Analysis

Citar esto

Amador-Patarroyo, M. J., Arbelaez, J. G., Mantilla, R. D., Rodriguez-Rodriguez, A., Cárdenas-Roldán, J., Pineda-Tamayo, R., ... Anaya, J. M. (2012). Sjögren's syndrome at the crossroad of polyautoimmunity. Journal of Autoimmunity, 199-205. https://doi.org/10.1016/j.jaut.2012.05.008
Amador-Patarroyo, Manuel J. ; Arbelaez, Juan Guillermo ; Mantilla, Ruben D. ; Rodriguez-Rodriguez, Alberto ; Cárdenas-Roldán, Jorge ; Pineda-Tamayo, Ricardo ; Guarin, Mayra R. ; Kleine, Liliana Lopez ; Rojas-Villarraga, Adriana ; Anaya, Juan Manuel. / Sjögren's syndrome at the crossroad of polyautoimmunity. En: Journal of Autoimmunity. 2012 ; pp. 199-205.
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abstract = "The coexistence of autoimmune diseases (i.e., polyautoimmunity) in Sj{\"o}gren's syndrome (SS) was investigated in a cross-sectional study involving 410 patients. Logistic regression analysis and the Rogers and Tanimoto index were used to evaluate risk factors and clustering, respectively. There were 134 (32.6{\%}) patients with polyautoimmunity. The most frequent and closer coexistent diseases were autoimmune thyroid disease (21.5{\%}), rheumatoid arthritis (8.3{\%}), systemic lupus erythematosus (7.6{\%}), and inflammatory bowel disease (0.7{\%}) which together constituted a cluster group. There were 35 (8.5{\%}) patients with multiple autoimmune syndrome. Besides disease duration, a history of habitual smoking and spontaneous abortion were found to be risk factors for the developing of polyautoimmunity. This study discloses a high prevalence of polyautoimmunity in SS, its associated risk factors and the grouping pattern of such a condition. These results may serve to define plausible approaches to study the common mechanisms of autoimmune diseases. {\circledC} 2012 Elsevier Ltd.",
author = "Amador-Patarroyo, {Manuel J.} and Arbelaez, {Juan Guillermo} and Mantilla, {Ruben D.} and Alberto Rodriguez-Rodriguez and Jorge C{\'a}rdenas-Rold{\'a}n and Ricardo Pineda-Tamayo and Guarin, {Mayra R.} and Kleine, {Liliana Lopez} and Adriana Rojas-Villarraga and Anaya, {Juan Manuel}",
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Amador-Patarroyo, MJ, Arbelaez, JG, Mantilla, RD, Rodriguez-Rodriguez, A, Cárdenas-Roldán, J, Pineda-Tamayo, R, Guarin, MR, Kleine, LL, Rojas-Villarraga, A & Anaya, JM 2012, 'Sjögren's syndrome at the crossroad of polyautoimmunity', Journal of Autoimmunity, pp. 199-205. https://doi.org/10.1016/j.jaut.2012.05.008

Sjögren's syndrome at the crossroad of polyautoimmunity. / Amador-Patarroyo, Manuel J.; Arbelaez, Juan Guillermo; Mantilla, Ruben D.; Rodriguez-Rodriguez, Alberto; Cárdenas-Roldán, Jorge; Pineda-Tamayo, Ricardo; Guarin, Mayra R.; Kleine, Liliana Lopez; Rojas-Villarraga, Adriana; Anaya, Juan Manuel.

En: Journal of Autoimmunity, 01.09.2012, p. 199-205.

Resultado de la investigación: Contribución a RevistaArtículo

TY - JOUR

T1 - Sjögren's syndrome at the crossroad of polyautoimmunity

AU - Amador-Patarroyo, Manuel J.

AU - Arbelaez, Juan Guillermo

AU - Mantilla, Ruben D.

AU - Rodriguez-Rodriguez, Alberto

AU - Cárdenas-Roldán, Jorge

AU - Pineda-Tamayo, Ricardo

AU - Guarin, Mayra R.

AU - Kleine, Liliana Lopez

AU - Rojas-Villarraga, Adriana

AU - Anaya, Juan Manuel

PY - 2012/9/1

Y1 - 2012/9/1

N2 - The coexistence of autoimmune diseases (i.e., polyautoimmunity) in Sjögren's syndrome (SS) was investigated in a cross-sectional study involving 410 patients. Logistic regression analysis and the Rogers and Tanimoto index were used to evaluate risk factors and clustering, respectively. There were 134 (32.6%) patients with polyautoimmunity. The most frequent and closer coexistent diseases were autoimmune thyroid disease (21.5%), rheumatoid arthritis (8.3%), systemic lupus erythematosus (7.6%), and inflammatory bowel disease (0.7%) which together constituted a cluster group. There were 35 (8.5%) patients with multiple autoimmune syndrome. Besides disease duration, a history of habitual smoking and spontaneous abortion were found to be risk factors for the developing of polyautoimmunity. This study discloses a high prevalence of polyautoimmunity in SS, its associated risk factors and the grouping pattern of such a condition. These results may serve to define plausible approaches to study the common mechanisms of autoimmune diseases. © 2012 Elsevier Ltd.

AB - The coexistence of autoimmune diseases (i.e., polyautoimmunity) in Sjögren's syndrome (SS) was investigated in a cross-sectional study involving 410 patients. Logistic regression analysis and the Rogers and Tanimoto index were used to evaluate risk factors and clustering, respectively. There were 134 (32.6%) patients with polyautoimmunity. The most frequent and closer coexistent diseases were autoimmune thyroid disease (21.5%), rheumatoid arthritis (8.3%), systemic lupus erythematosus (7.6%), and inflammatory bowel disease (0.7%) which together constituted a cluster group. There were 35 (8.5%) patients with multiple autoimmune syndrome. Besides disease duration, a history of habitual smoking and spontaneous abortion were found to be risk factors for the developing of polyautoimmunity. This study discloses a high prevalence of polyautoimmunity in SS, its associated risk factors and the grouping pattern of such a condition. These results may serve to define plausible approaches to study the common mechanisms of autoimmune diseases. © 2012 Elsevier Ltd.

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DO - 10.1016/j.jaut.2012.05.008

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SP - 199

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JO - Journal of Autoimmunity

JF - Journal of Autoimmunity

SN - 0896-8411

ER -

Amador-Patarroyo MJ, Arbelaez JG, Mantilla RD, Rodriguez-Rodriguez A, Cárdenas-Roldán J, Pineda-Tamayo R y otros. Sjögren's syndrome at the crossroad of polyautoimmunity. Journal of Autoimmunity. 2012 sep 1;199-205. https://doi.org/10.1016/j.jaut.2012.05.008