Simple proteomic checks for detecting noncoding RNA

Stéphane Cruveiller; Oliver Clay; Kamel Jabbari; Giorgio Bernardi

doi:10.1002/pmic.200600813

Simple proteomic checks for detecting noncoding RNA

Stéphane Cruveiller
, Oliver Clay
, Kamel Jabbari
, Giorgio Bernardi

Producción científica: Contribución a revista › Artículo de Investigación › revisión exhaustiva

6 Citas (Scopus)

Resumen

Proper validation can accelerate sequence-based discovery of proteins and protein-coding genes. Databases currently contain a backlog of experimentally unverified gene models and tentative assignments of observed transcripts to coding or noncoding RNA. We present and apply a general principle, founded on base composition and the genetic code and validated here by bulk 2-D gels, that can improve the reliability of such classifications and of the algorithms or pipelines that lead to them.

Idioma original	Inglés estadounidense
Páginas (desde-hasta)	361-363
Número de páginas	3
Publicación	Proteomics
Volumen	7
N.º	3
DOI	https://doi.org/10.1002/pmic.200600813
Estado	Publicada - feb. 2007
Publicado de forma externa	Sí

Áreas temáticas de ASJC Scopus

Bioquímica
Biología molecular

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10.1002/pmic.200600813

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AB - Proper validation can accelerate sequence-based discovery of proteins and protein-coding genes. Databases currently contain a backlog of experimentally unverified gene models and tentative assignments of observed transcripts to coding or noncoding RNA. We present and apply a general principle, founded on base composition and the genetic code and validated here by bulk 2-D gels, that can improve the reliability of such classifications and of the algorithms or pipelines that lead to them.

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Simple proteomic checks for detecting noncoding RNA

Resumen

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