Vogt-Koyanagi-Harada Syndrome in a Group of Patients in Two Ophthalmology Referral Centers in Bogotá, Colombia. VKH syndrome in Colombia

Título traducido de la contribución: Síndrome de Vogt-Koyanagi-Harada en un grupo de pacientes en dos centros de referencia de oftalmología en Bogotá, Colombia.

Ligia Alejandra De La Torre Cifuentes, Carol Guayacán, Brahyan Galindo-Mendez

Resultado de la investigación: Contribución a RevistaArtículo

Resumen

PROPÓSITO:
Describir la presentación clínica del síndrome de Vogt-Koyanagi-Harada (VKH) en un grupo de pacientes en Colombia.

MÉTODOS:
Revisión retrospectiva de 2638 historias clínicas de pacientes con uveítis en dos centros durante 17 años.

RESULTADOS:
Un total de 25 pacientes con uveítis fueron diagnosticados con el síndrome de VKH (0,95%), 23 pacientes fueron incluidos en el análisis de datos (0,87%), 78,3% mujeres, y la edad media de diagnóstico fue de 37 años (DE ± 29). Principales quejas: visión borrosa (87%), cefaleas (47,8%), tinnitus (26,1%) y deficiencias auditivas (21,7%). Hallazgos oftálmicos: desprendimiento seroso bilateral de retina (73,9%) y uveítis no granulomatosa (52,3%). La mayoría de los pacientes fueron diagnosticados con enfermedad probable (56.5%). La duración media del seguimiento fue de 14 meses; se encontró recaída de la enfermedad en el 26% de los pacientes a pesar del tratamiento.

CONCLUSIÓN:
Los pacientes en Colombia con VKH tuvieron características clínicas similares a las reportadas en otras poblaciones hispanas, excepto por la uveítis no granulomatosa. Se puede considerar que esta enfermedad tiene una variación de las manifestaciones clínicas entre los grupos de población.
Idioma originalEnglish (US)
Número de artículoNOII 2016-0391
Páginas (desde-hasta)1-13
Número de páginas13
PublicaciónOcular Immunology and Inflammation
DOI
EstadoPublished - sep 14 2017

Huella dactilar

Uveomeningoencephalitic Syndrome
Colombia
Ophthalmology
Referral and Consultation
Uveitis
Tinnitus
Retinal Detachment
Hearing Loss
Population Groups
Hispanic Americans
Medical Records
Headache
Demography
Recurrence

Citar esto

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title = "Vogt-Koyanagi-Harada Syndrome in a Group of Patients in Two Ophthalmology Referral Centers in Bogot{\'a}, Colombia.: VKH syndrome in Colombia",
abstract = "Purpose: To describe the clinical presentation of Vogt-Koyanagi-Harada syndrome in a group of patients in Colombia.Methods: Retrospective-review of 2638 medical-records of patients with uveitis in two centers during 17 years. Patients with Vogt-Koyanagi-Harada syndrome were gathered to characterize demographic and clinical data. Results: Twenty-five patients with uveitis were diagnosed with Vogt-Koyanagi-Harada syndrome (0.95{\%}), 78.3{\%} females, mean age of diagnosis 37 years old (SD ±29). Twenty-three patients with complete data were included. Main complaints: blurred vision (87{\%}), headaches (47.8{\%}), tinnitus (26.1{\%}) and hearing impairments (21.7{\%}). Ophthalmic findings: bilateral serous retinal-detachment (67.4{\%}), non-granulomatous uveitis (52.3{\%}). Most of the patients were diagnosed with probable disease (56.5{\%}). Mean duration of follow-up was fourteen months; disease relapse was encountered in 26{\%} of patients despite treatment. Conclusion: Patients in Colombia with Vogt-Koyanagi-Harada had clinical features similar to those reported in other Hispanic populations, except for the non-granulomatous uveitis. This disease may be considered as having variation of clinical manifestations across population groups.",
author = "{De La Torre Cifuentes}, {Ligia Alejandra} and Carol Guayac{\'a}n and Brahyan Galindo-Mendez",
year = "2017",
month = "9",
day = "14",
doi = "10.1080/09273948.2017.1341536",
language = "English (US)",
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journal = "Ocular Immunology and Inflammation",
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Vogt-Koyanagi-Harada Syndrome in a Group of Patients in Two Ophthalmology Referral Centers in Bogotá, Colombia. VKH syndrome in Colombia. / De La Torre Cifuentes, Ligia Alejandra; Guayacán, Carol; Galindo-Mendez, Brahyan.

En: Ocular Immunology and Inflammation, 14.09.2017, p. 1-13.

Resultado de la investigación: Contribución a RevistaArtículo

TY - JOUR

T1 - Vogt-Koyanagi-Harada Syndrome in a Group of Patients in Two Ophthalmology Referral Centers in Bogotá, Colombia.

T2 - VKH syndrome in Colombia

AU - De La Torre Cifuentes, Ligia Alejandra

AU - Guayacán, Carol

AU - Galindo-Mendez, Brahyan

PY - 2017/9/14

Y1 - 2017/9/14

N2 - Purpose: To describe the clinical presentation of Vogt-Koyanagi-Harada syndrome in a group of patients in Colombia.Methods: Retrospective-review of 2638 medical-records of patients with uveitis in two centers during 17 years. Patients with Vogt-Koyanagi-Harada syndrome were gathered to characterize demographic and clinical data. Results: Twenty-five patients with uveitis were diagnosed with Vogt-Koyanagi-Harada syndrome (0.95%), 78.3% females, mean age of diagnosis 37 years old (SD ±29). Twenty-three patients with complete data were included. Main complaints: blurred vision (87%), headaches (47.8%), tinnitus (26.1%) and hearing impairments (21.7%). Ophthalmic findings: bilateral serous retinal-detachment (67.4%), non-granulomatous uveitis (52.3%). Most of the patients were diagnosed with probable disease (56.5%). Mean duration of follow-up was fourteen months; disease relapse was encountered in 26% of patients despite treatment. Conclusion: Patients in Colombia with Vogt-Koyanagi-Harada had clinical features similar to those reported in other Hispanic populations, except for the non-granulomatous uveitis. This disease may be considered as having variation of clinical manifestations across population groups.

AB - Purpose: To describe the clinical presentation of Vogt-Koyanagi-Harada syndrome in a group of patients in Colombia.Methods: Retrospective-review of 2638 medical-records of patients with uveitis in two centers during 17 years. Patients with Vogt-Koyanagi-Harada syndrome were gathered to characterize demographic and clinical data. Results: Twenty-five patients with uveitis were diagnosed with Vogt-Koyanagi-Harada syndrome (0.95%), 78.3% females, mean age of diagnosis 37 years old (SD ±29). Twenty-three patients with complete data were included. Main complaints: blurred vision (87%), headaches (47.8%), tinnitus (26.1%) and hearing impairments (21.7%). Ophthalmic findings: bilateral serous retinal-detachment (67.4%), non-granulomatous uveitis (52.3%). Most of the patients were diagnosed with probable disease (56.5%). Mean duration of follow-up was fourteen months; disease relapse was encountered in 26% of patients despite treatment. Conclusion: Patients in Colombia with Vogt-Koyanagi-Harada had clinical features similar to those reported in other Hispanic populations, except for the non-granulomatous uveitis. This disease may be considered as having variation of clinical manifestations across population groups.

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