Tubulointerstitial Nephritis and Uveitis Syndrome: Case Report and Review of the Literature

María Camila Aguilar; Marcela Lonngi; Alejandra de-la-Torre

doi:10.3109/09273948.2015.1034374

Tubulointerstitial Nephritis and Uveitis Syndrome: Case Report and Review of the Literature

Título traducido de la contribución: Síndrome de nefritis tubulointersticial y uveítis: presentación de un caso y revisión de la literatura

María Camila Aguilar, Marcela Lonngi, Alejandra de-la-Torre

Producción científica: Contribución a una revista › Reseña científica › revisión exhaustiva

12 Citas (Scopus)

Resumen

Objetivo: revisar la literatura sobre el síndrome de nefritis tubulointersticial y uveítis (TINU) y reportar un caso de un paciente con policondritis recidivante (PR) y síndrome TINU. Método: el síndrome TINU es un trastorno inflamatorio oculorenal raro. Es más común en mujeres jóvenes con condiciones autoinmunes, infecciones, enfermedades sistémicas y uso previo de medicamentos. Divulgamos el caso de una mujer de 62 años con policondritis recidivante y una historia de 2 años de uveítis aguda, recurrente, asimétrica, bilateral, anterior, no granulomatosa acompañada de nefritis tubulointersticial. Resultados: el paciente fue diagnosticado con síndrome TINU asociado a policondritis recidivante. No se han reportado casos de esta asociación en la literatura. Las características clínicas del síndrome TINU se discuten en base a los trabajos publicados. Conclusiones: TINU es un síndrome poco común; solo alrededor de 200 casos han sido reportados en la literatura relacionada con infecciones, enfermedades sistémicas y uso previo de medicamentos como antibióticos y antiinflamatorios no esteroideos (AINE). Encontramos que puede asociarse con policondritis recidivante; por lo tanto, es importante investigar los síntomas de esta enfermedad ya que el síndrome TINU puede coexistir con ella

Título traducido de la contribución	Síndrome de nefritis tubulointersticial y uveítis: presentación de un caso y revisión de la literatura
Idioma original	Inglés estadounidense
Páginas (desde-hasta)	415-421
Número de páginas	7
Publicación	Ocular Immunology and Inflammation
Volumen	24
N.º	4
DOI	https://doi.org/10.3109/09273948.2015.1034374
Estado	Publicada - jul. 3 2016

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@article{8e93a678aa73424a88d5aff27ab4cfdc,

title = "Tubulointerstitial Nephritis and Uveitis Syndrome: Case Report and Review of the Literature",

abstract = "Purpose: To review the literature on tubulointerstitial nephritis and uveitis (TINU) syndrome, and to report a case of a patient with relapsing polychondritis (RP) and TINU syndrome. Method: TINU syndrome is a rare oculorenal inflammatory disorder. It is more common in young women with autoimmune conditions, infections, systemic disease, and previous use of medications. We report the case of a 62-year-old woman with relapsing polychondritis and a 2-year history of acute, recurrent, asymmetric, bilateral, anterior, non-granulomatous uveitis accompanied by tubulointerstitial nephritis. Results: The patient was diagnosed with TINU syndrome associated with relapsing polychondritis. No cases of this association have been reported in the literature. The clinical features of TINU syndrome are discussed based on the published works. Conclusions: TINU is an uncommon syndrome; only about 200 cases have been reported in the literature related to infections, systemic disease, and previous use of medications such as antibiotics and non-steroidal anti-inflammatory drugs (NSAIDs). We found that it can be associated with relapsing polychondritis; therefore, it is important to investigate symptoms of this disease since TINU syndrome can co-exist with it.",

author = "Aguilar, {Mar{\'i}a Camila} and Marcela Lonngi and Alejandra de-la-Torre",

year = "2016",

month = jul,

day = "3",

doi = "10.3109/09273948.2015.1034374",

language = "English (US)",

volume = "24",

pages = "415--421",

journal = "Ocular Immunology and Inflammation",

issn = "0927-3948",

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number = "4",

}

TY - JOUR

T1 - Tubulointerstitial Nephritis and Uveitis Syndrome: Case Report and Review of the Literature

AU - Aguilar, María Camila

AU - Lonngi, Marcela

AU - de-la-Torre, Alejandra

PY - 2016/7/3

Y1 - 2016/7/3

N2 - Purpose: To review the literature on tubulointerstitial nephritis and uveitis (TINU) syndrome, and to report a case of a patient with relapsing polychondritis (RP) and TINU syndrome. Method: TINU syndrome is a rare oculorenal inflammatory disorder. It is more common in young women with autoimmune conditions, infections, systemic disease, and previous use of medications. We report the case of a 62-year-old woman with relapsing polychondritis and a 2-year history of acute, recurrent, asymmetric, bilateral, anterior, non-granulomatous uveitis accompanied by tubulointerstitial nephritis. Results: The patient was diagnosed with TINU syndrome associated with relapsing polychondritis. No cases of this association have been reported in the literature. The clinical features of TINU syndrome are discussed based on the published works. Conclusions: TINU is an uncommon syndrome; only about 200 cases have been reported in the literature related to infections, systemic disease, and previous use of medications such as antibiotics and non-steroidal anti-inflammatory drugs (NSAIDs). We found that it can be associated with relapsing polychondritis; therefore, it is important to investigate symptoms of this disease since TINU syndrome can co-exist with it.

AB - Purpose: To review the literature on tubulointerstitial nephritis and uveitis (TINU) syndrome, and to report a case of a patient with relapsing polychondritis (RP) and TINU syndrome. Method: TINU syndrome is a rare oculorenal inflammatory disorder. It is more common in young women with autoimmune conditions, infections, systemic disease, and previous use of medications. We report the case of a 62-year-old woman with relapsing polychondritis and a 2-year history of acute, recurrent, asymmetric, bilateral, anterior, non-granulomatous uveitis accompanied by tubulointerstitial nephritis. Results: The patient was diagnosed with TINU syndrome associated with relapsing polychondritis. No cases of this association have been reported in the literature. The clinical features of TINU syndrome are discussed based on the published works. Conclusions: TINU is an uncommon syndrome; only about 200 cases have been reported in the literature related to infections, systemic disease, and previous use of medications such as antibiotics and non-steroidal anti-inflammatory drugs (NSAIDs). We found that it can be associated with relapsing polychondritis; therefore, it is important to investigate symptoms of this disease since TINU syndrome can co-exist with it.

U2 - 10.3109/09273948.2015.1034374

DO - 10.3109/09273948.2015.1034374

M3 - Literature review

C2 - 26400208

SN - 0927-3948

VL - 24

SP - 415

EP - 421

JO - Ocular Immunology and Inflammation

JF - Ocular Immunology and Inflammation

IS - 4

ER -

Tubulointerstitial Nephritis and Uveitis Syndrome: Case Report and Review of the Literature

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