Relationship between handgrip strength and muscle mass in female survivors of breast cancer

A mediation analysis

Lorena Benavides-Rodríguez, Antonio García-Hermoso, Diogo Rodrigues-Bezerra, Mikel Izquierdo, Jorge Enrique Correa-Bautista, Robinson Ramírez-Vélez

Resultado de la investigación: Contribución a RevistaArtículo

2 Citas (Scopus)

Resumen

This study explored the mediating factors of sarcopenia in a group of women survivors of breast cancer in Bogotá, Colombia. This was a descriptive cross-sectional study with 98 women survivors of breast cancer, who were registered with the SIMMON (Integrated Synergies to Improve Oncological Management in Colombia) Foundation. Body weight, height, and waist circumference (WC) were measured, and body mass index (BMI) was calculated. Body composition (percentage of fat and muscle mass) was evaluated via four-pole bioelectrical impedance analysis. Sarcopenia was defined as low muscle mass plus low grip strength or low gait speed (European Working Group on Sarcopenia in Older People (EWGSOP) criteria). A “causal” mediation analysis with the Baron & Kenny procedure (PROCESS® macro, Columbus, OH, USA) was used to explore variables related to sarcopenia. Analyses were performed with the IBM SPSS 21 statistical package (SPSS Inc., Chicago, IL, USA). The significance level of the results obtained in the hypothesis contrast was p < 0.05. The mean age of the sample was 65.5 ± 5.9 years, with a BMI of 27.8 ± 4.7 kg/m2. The prevalence of sarcopenia was 22.4%. Linear regression models suggest a partial mediation of anthropometric parameters (body mass, body mass index and waist circumference) in the association between handgrip strength and muscle mass. In conclusion, one in every five women survivors of breast cancer had sarcopenia. The findings seem to emphasize the importance of obesity prevention in women survivors of breast cancer, suggesting that high handgrip strength may not relate closely to greater muscle mass and therefore would not exclude the risk of sarcopenia.

Idioma originalEnglish (US)
Número de artículo695
PublicaciónNutrients
Volumen9
N.º7
DOI
EstadoPublished - jul 4 2017
Publicado de forma externa

Huella dactilar

sarcopenia
Sarcopenia
Muscle Strength
breast neoplasms
Survivors
Breast Neoplasms
muscles
body mass index
Body Mass Index
Colombia
waist circumference
Waist Circumference
Muscles
Linear Models
Body Height
bioelectrical impedance
Hand Strength
gait
Body Composition
Electric Impedance

All Science Journal Classification (ASJC) codes

  • Food Science

Citar esto

Benavides-Rodríguez, L., García-Hermoso, A., Rodrigues-Bezerra, D., Izquierdo, M., Correa-Bautista, J. E., & Ramírez-Vélez, R. (2017). Relationship between handgrip strength and muscle mass in female survivors of breast cancer: A mediation analysis. Nutrients, 9(7), [695]. https://doi.org/10.3390/nu9070695
Benavides-Rodríguez, Lorena ; García-Hermoso, Antonio ; Rodrigues-Bezerra, Diogo ; Izquierdo, Mikel ; Correa-Bautista, Jorge Enrique ; Ramírez-Vélez, Robinson. / Relationship between handgrip strength and muscle mass in female survivors of breast cancer : A mediation analysis. En: Nutrients. 2017 ; Vol. 9, N.º 7.
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abstract = "This study explored the mediating factors of sarcopenia in a group of women survivors of breast cancer in Bogot{\'a}, Colombia. This was a descriptive cross-sectional study with 98 women survivors of breast cancer, who were registered with the SIMMON (Integrated Synergies to Improve Oncological Management in Colombia) Foundation. Body weight, height, and waist circumference (WC) were measured, and body mass index (BMI) was calculated. Body composition (percentage of fat and muscle mass) was evaluated via four-pole bioelectrical impedance analysis. Sarcopenia was defined as low muscle mass plus low grip strength or low gait speed (European Working Group on Sarcopenia in Older People (EWGSOP) criteria). A “causal” mediation analysis with the Baron & Kenny procedure (PROCESS{\circledR} macro, Columbus, OH, USA) was used to explore variables related to sarcopenia. Analyses were performed with the IBM SPSS 21 statistical package (SPSS Inc., Chicago, IL, USA). The significance level of the results obtained in the hypothesis contrast was p < 0.05. The mean age of the sample was 65.5 ± 5.9 years, with a BMI of 27.8 ± 4.7 kg/m2. The prevalence of sarcopenia was 22.4{\%}. Linear regression models suggest a partial mediation of anthropometric parameters (body mass, body mass index and waist circumference) in the association between handgrip strength and muscle mass. In conclusion, one in every five women survivors of breast cancer had sarcopenia. The findings seem to emphasize the importance of obesity prevention in women survivors of breast cancer, suggesting that high handgrip strength may not relate closely to greater muscle mass and therefore would not exclude the risk of sarcopenia.",
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Benavides-Rodríguez, L, García-Hermoso, A, Rodrigues-Bezerra, D, Izquierdo, M, Correa-Bautista, JE & Ramírez-Vélez, R 2017, 'Relationship between handgrip strength and muscle mass in female survivors of breast cancer: A mediation analysis', Nutrients, vol. 9, n.º 7, 695. https://doi.org/10.3390/nu9070695

Relationship between handgrip strength and muscle mass in female survivors of breast cancer : A mediation analysis. / Benavides-Rodríguez, Lorena; García-Hermoso, Antonio; Rodrigues-Bezerra, Diogo; Izquierdo, Mikel; Correa-Bautista, Jorge Enrique; Ramírez-Vélez, Robinson.

En: Nutrients, Vol. 9, N.º 7, 695, 04.07.2017.

Resultado de la investigación: Contribución a RevistaArtículo

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AU - Ramírez-Vélez, Robinson

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Benavides-Rodríguez L, García-Hermoso A, Rodrigues-Bezerra D, Izquierdo M, Correa-Bautista JE, Ramírez-Vélez R. Relationship between handgrip strength and muscle mass in female survivors of breast cancer: A mediation analysis. Nutrients. 2017 jul 4;9(7). 695. https://doi.org/10.3390/nu9070695