Prevalence and clinical features of multiple sclerosis in Latin America

Ernesto Ojeda, Diana Díaz-Cortes, Dominique Rosales, Carolina Duarte-Rey, Juan Manuel Anaya, Adriana Rojas-Villarraga

Resultado de la investigación: Contribución a RevistaRevisión Literaria

11 Citas (Scopus)

Resumen

Multiple sclerosis (MS) in Latin America (LA) is considered to have a low to medium prevalence. However, accurate information on MS in LA is scarce. The aim of this study was to compare clinical characteristics among LA patients through a systematic review of the literature. A systematic search (Spanish, Portuguese and English) was done for all clinical studies of MS in humans (MEDLINE, PubMed, Scielo, BIREME, EMBASE and LILACS) up to May 2011 being focused on a well-defined Latin American population (peer-reviewed journal) following the MOOSE guidelines. The search strategy included combinations of different Mesh terms (two independent researchers). Classification of each article by using the Oxford Centre for Evidence-based Medicine-Levels of Evidence was done. The total number of patients per country for each specific characteristic was compiled. Chi-square test was used to compare the characteristics in the studies retrieved per country. There were 38 articles fulfilling the inclusion criteria, accounting for 4524 patients. Relapsing-remitting form was the most frequent in LA patients and the main initial symptom was motor, followed by optic neuritis and sensorial. A mild expanded disability status scale was the most prevalent in all LA countries. Factors accounting for differences in distribution and clinical course across LA countries include genetics, environment, diagnostic techniques, socioeconomic structure and medical facilities. © 2012 Elsevier B.V.
Idioma originalEnglish (US)
Páginas (desde-hasta)381-387
Número de páginas7
PublicaciónClinical Neurology and Neurosurgery
DOI
EstadoPublished - abr 1 2013

Huella dactilar

Latin America
Multiple Sclerosis
Hospital Distribution Systems
Optic Neuritis
Evidence-Based Medicine
Chi-Square Distribution
PubMed
MEDLINE
Research Personnel
Guidelines
Population

Citar esto

Ojeda, E., Díaz-Cortes, D., Rosales, D., Duarte-Rey, C., Anaya, J. M., & Rojas-Villarraga, A. (2013). Prevalence and clinical features of multiple sclerosis in Latin America. Clinical Neurology and Neurosurgery, 381-387. https://doi.org/10.1016/j.clineuro.2012.11.028
Ojeda, Ernesto ; Díaz-Cortes, Diana ; Rosales, Dominique ; Duarte-Rey, Carolina ; Anaya, Juan Manuel ; Rojas-Villarraga, Adriana. / Prevalence and clinical features of multiple sclerosis in Latin America. En: Clinical Neurology and Neurosurgery. 2013 ; pp. 381-387.
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abstract = "Multiple sclerosis (MS) in Latin America (LA) is considered to have a low to medium prevalence. However, accurate information on MS in LA is scarce. The aim of this study was to compare clinical characteristics among LA patients through a systematic review of the literature. A systematic search (Spanish, Portuguese and English) was done for all clinical studies of MS in humans (MEDLINE, PubMed, Scielo, BIREME, EMBASE and LILACS) up to May 2011 being focused on a well-defined Latin American population (peer-reviewed journal) following the MOOSE guidelines. The search strategy included combinations of different Mesh terms (two independent researchers). Classification of each article by using the Oxford Centre for Evidence-based Medicine-Levels of Evidence was done. The total number of patients per country for each specific characteristic was compiled. Chi-square test was used to compare the characteristics in the studies retrieved per country. There were 38 articles fulfilling the inclusion criteria, accounting for 4524 patients. Relapsing-remitting form was the most frequent in LA patients and the main initial symptom was motor, followed by optic neuritis and sensorial. A mild expanded disability status scale was the most prevalent in all LA countries. Factors accounting for differences in distribution and clinical course across LA countries include genetics, environment, diagnostic techniques, socioeconomic structure and medical facilities. {\circledC} 2012 Elsevier B.V.",
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Ojeda, E, Díaz-Cortes, D, Rosales, D, Duarte-Rey, C, Anaya, JM & Rojas-Villarraga, A 2013, 'Prevalence and clinical features of multiple sclerosis in Latin America', Clinical Neurology and Neurosurgery, pp. 381-387. https://doi.org/10.1016/j.clineuro.2012.11.028

Prevalence and clinical features of multiple sclerosis in Latin America. / Ojeda, Ernesto; Díaz-Cortes, Diana; Rosales, Dominique; Duarte-Rey, Carolina; Anaya, Juan Manuel; Rojas-Villarraga, Adriana.

En: Clinical Neurology and Neurosurgery, 01.04.2013, p. 381-387.

Resultado de la investigación: Contribución a RevistaRevisión Literaria

TY - JOUR

T1 - Prevalence and clinical features of multiple sclerosis in Latin America

AU - Ojeda, Ernesto

AU - Díaz-Cortes, Diana

AU - Rosales, Dominique

AU - Duarte-Rey, Carolina

AU - Anaya, Juan Manuel

AU - Rojas-Villarraga, Adriana

PY - 2013/4/1

Y1 - 2013/4/1

N2 - Multiple sclerosis (MS) in Latin America (LA) is considered to have a low to medium prevalence. However, accurate information on MS in LA is scarce. The aim of this study was to compare clinical characteristics among LA patients through a systematic review of the literature. A systematic search (Spanish, Portuguese and English) was done for all clinical studies of MS in humans (MEDLINE, PubMed, Scielo, BIREME, EMBASE and LILACS) up to May 2011 being focused on a well-defined Latin American population (peer-reviewed journal) following the MOOSE guidelines. The search strategy included combinations of different Mesh terms (two independent researchers). Classification of each article by using the Oxford Centre for Evidence-based Medicine-Levels of Evidence was done. The total number of patients per country for each specific characteristic was compiled. Chi-square test was used to compare the characteristics in the studies retrieved per country. There were 38 articles fulfilling the inclusion criteria, accounting for 4524 patients. Relapsing-remitting form was the most frequent in LA patients and the main initial symptom was motor, followed by optic neuritis and sensorial. A mild expanded disability status scale was the most prevalent in all LA countries. Factors accounting for differences in distribution and clinical course across LA countries include genetics, environment, diagnostic techniques, socioeconomic structure and medical facilities. © 2012 Elsevier B.V.

AB - Multiple sclerosis (MS) in Latin America (LA) is considered to have a low to medium prevalence. However, accurate information on MS in LA is scarce. The aim of this study was to compare clinical characteristics among LA patients through a systematic review of the literature. A systematic search (Spanish, Portuguese and English) was done for all clinical studies of MS in humans (MEDLINE, PubMed, Scielo, BIREME, EMBASE and LILACS) up to May 2011 being focused on a well-defined Latin American population (peer-reviewed journal) following the MOOSE guidelines. The search strategy included combinations of different Mesh terms (two independent researchers). Classification of each article by using the Oxford Centre for Evidence-based Medicine-Levels of Evidence was done. The total number of patients per country for each specific characteristic was compiled. Chi-square test was used to compare the characteristics in the studies retrieved per country. There were 38 articles fulfilling the inclusion criteria, accounting for 4524 patients. Relapsing-remitting form was the most frequent in LA patients and the main initial symptom was motor, followed by optic neuritis and sensorial. A mild expanded disability status scale was the most prevalent in all LA countries. Factors accounting for differences in distribution and clinical course across LA countries include genetics, environment, diagnostic techniques, socioeconomic structure and medical facilities. © 2012 Elsevier B.V.

U2 - 10.1016/j.clineuro.2012.11.028

DO - 10.1016/j.clineuro.2012.11.028

M3 - Literature review

SP - 381

EP - 387

JO - Clinical Neurology and Neurosurgery

JF - Clinical Neurology and Neurosurgery

SN - 0303-8467

ER -

Ojeda E, Díaz-Cortes D, Rosales D, Duarte-Rey C, Anaya JM, Rojas-Villarraga A. Prevalence and clinical features of multiple sclerosis in Latin America. Clinical Neurology and Neurosurgery. 2013 abr 1;381-387. https://doi.org/10.1016/j.clineuro.2012.11.028