Preprocessing by means of subspace projections for continuous Cerebral Autoregulation assessment using NIRS

A. Caicedo, G. Naulaers, S. Van Huffel

Resultado de la investigación: Capítulo en Libro/Reporte/ConferenciaContribución a la conferencia

5 Citas (Scopus)

Resumen

Cerebral Autoregulation (CA) refers to the capability of the brain to maintain a more or less stable cerebral blood flow (CBF), despite the changes in blood perfusion. Monitoring this mechanism is of vital importance, especially in neonates, in order to prevent damage due to ischemia or hemorrhage. In clinical practice near-infrared spectroscopy (NIRS) measurements are used as a surrogate measurement for CBF. However, NIRS signals are highly dependent on the variations in arterial oxygen saturation (SaO2). Therefore, only segments with relatively constant SaO2 are used for CA assessment; which limits the possibilities of the use of NIRS for online monitoring. In this paper we propose the use of subspace projections to subtract the influence of SaO2 from NIRS measurements. Since this approach will be used in an online monitoring system, this preprocessing is carried out in a window-by-window framework. However, the use of subspace projections in consecutive segments produces discontinuities; we propose a methodology to reduce these effects. Obtained results indicate that the proposed method reduces the effect of discontinuities between consecutive segments. In addition, this methodology is able to subtract the influence of SaO2 from NIRS measurements. This approach facilitates the introduction of NIRS for online CA assessment.

Idioma originalInglés estadounidense
Título de la publicación alojada2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2013
Páginas2032-2035
Número de páginas4
DOI
EstadoPublicada - 2013
Publicado de forma externa
Evento2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2013 - Osaka, Japón
Duración: jul 3 2013jul 7 2013

Serie de la publicación

NombreProceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS
ISSN (versión impresa)1557-170X

Conferencia

Conferencia2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2013
País/TerritorioJapón
CiudadOsaka
Período7/3/137/7/13

All Science Journal Classification (ASJC) codes

  • Procesamiento de senales
  • Ingeniería biomédica
  • Visión artificial y reconocimiento de patrones
  • Informática aplicada a la salud

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