Posterior cortical atrophy misdiagnosed as typical Alzheimer's disease: Clinical and neuropsychological evolution over eight years. A case report

Posterior cortical atrophy (PCA) is a challenging diagnosis and is often misdiagnosed due to its subtle and atypical presentation. We present a woman with early-onset visuospatial dysfunction, apraxia, and dysgraphia. Neuroimaging revealed posterior atrophy with sparing of the hippocampi. Clinical features, neuropsychological findings, and neuroimaging were consistent with a diagnosis of PCA. The diagnosis was established based on the three-level PCA classification framework. This case highlights the importance of clinical evaluation and multidisciplinary collaboration in identifying atypical presentations of neurodegenerative diseases.