Resumen
Thrombotic microangiopathies (TMA) include a variety of vascular disorders characterized by
the presence of microthrombi, coagulopathy by platelet activation and consumption, and systemic damage. The most frequent secondary causes are infections and some medications.
However, the presence of chemotherapeutic agents is not so common, and the induction of
TMA by oxaliplatin is poorly understood, with few published case reports. We present the case
of a patient with a history of gallbladder carcinoma, in whom findings compatible with TMA
were documented, and with a temporal and sole relation to oxaliplatin.
the presence of microthrombi, coagulopathy by platelet activation and consumption, and systemic damage. The most frequent secondary causes are infections and some medications.
However, the presence of chemotherapeutic agents is not so common, and the induction of
TMA by oxaliplatin is poorly understood, with few published case reports. We present the case
of a patient with a history of gallbladder carcinoma, in whom findings compatible with TMA
were documented, and with a temporal and sole relation to oxaliplatin.
Título traducido de la contribución | MIcroangiopatia trombotica inducida por oxaliplatino, en un paciente con carcinoma de vesícula estadio IV. ¿causal directo o multifactorial? |
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Idioma original | Inglés estadounidense |
Páginas (desde-hasta) | 1191 |
Número de páginas | 1195 |
Publicación | Case Reports in Oncology |
Volumen | 13 |
Estado | Publicada - sep. 29 2020 |
Publicado de forma externa | Sí |