Noncoronary Vascular Calcification, Bone Mineral Density, and Muscle Mass in Institutionalized Frail Nonagenarians

Fernando Idoate, Eduardo L. Cadore, Alvaro Casas-Herrero, Fabricio Zambom-Ferraresi, Nicolas Martínez-Velilla, Leocadio Rodriguez-Mañas, Pedro M. Azcárate, Martim Bottaro, Robinson Ramírez-Vélez, Mikel Izquierdo

Resultado de la investigación: Contribución a RevistaArtículo

6 Citas (Scopus)

Resumen

The purpose of this study was to compare the vascular calcification in thoracic aorta (TAC), abdominal aorta (AAC), iliac arteries (IAC), and femoral arteries (FAC) and bone mineral density (BMD) of the lumbar vertebrae between frail and robust nonagenarians, as well as to verify the associations between vascular calcification with BMD, muscle tissue quality, and quantity in both groups. Forty-two elderly subjects participated in this study: 29 institutionalized frail (92.0 ± 3.2 years) and 13 robust (89.0 ± 4.0 years) elderly participants. All patients underwent nonenhanced helical thoracic, abdominal, and thigh computed tomography. The frail group presented significantly greater FAC as well as less lumbar BMD than the robust group (p < 0.05). In the frail group, significant negative relationships were observed between the individual values of FAC with the individual values of BMD (r = -0.35 to -0.43, p < 0.05) and with the individual values of the quadriceps muscle quantity and quality (r = -0.52, p < 0.01), whereas no significant relationships were observed in the robust group. The robust group presented less vascular calcification and more BMD in the vertebral bodies than the frail group. In the frail group, femoral artery calcification was significantly negatively correlated with BMD, leg muscle quality, and muscle mass volume.

Idioma originalEnglish (US)
Páginas (desde-hasta)298-308
Número de páginas11
PublicaciónRejuvenation Research
Volumen20
N.º4
DOI
EstadoPublished - ago 1 2017

All Science Journal Classification (ASJC) codes

  • Aging
  • Geriatrics and Gerontology

Citar esto

Idoate, F., Cadore, E. L., Casas-Herrero, A., Zambom-Ferraresi, F., Martínez-Velilla, N., Rodriguez-Mañas, L., ... Izquierdo, M. (2017). Noncoronary Vascular Calcification, Bone Mineral Density, and Muscle Mass in Institutionalized Frail Nonagenarians. Rejuvenation Research, 20(4), 298-308. https://doi.org/10.1089/rej.2016.1868
Idoate, Fernando ; Cadore, Eduardo L. ; Casas-Herrero, Alvaro ; Zambom-Ferraresi, Fabricio ; Martínez-Velilla, Nicolas ; Rodriguez-Mañas, Leocadio ; Azcárate, Pedro M. ; Bottaro, Martim ; Ramírez-Vélez, Robinson ; Izquierdo, Mikel. / Noncoronary Vascular Calcification, Bone Mineral Density, and Muscle Mass in Institutionalized Frail Nonagenarians. En: Rejuvenation Research. 2017 ; Vol. 20, N.º 4. pp. 298-308.
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title = "Noncoronary Vascular Calcification, Bone Mineral Density, and Muscle Mass in Institutionalized Frail Nonagenarians",
abstract = "The purpose of this study was to compare the vascular calcification in thoracic aorta (TAC), abdominal aorta (AAC), iliac arteries (IAC), and femoral arteries (FAC) and bone mineral density (BMD) of the lumbar vertebrae between frail and robust nonagenarians, as well as to verify the associations between vascular calcification with BMD, muscle tissue quality, and quantity in both groups. Forty-two elderly subjects participated in this study: 29 institutionalized frail (92.0 ± 3.2 years) and 13 robust (89.0 ± 4.0 years) elderly participants. All patients underwent nonenhanced helical thoracic, abdominal, and thigh computed tomography. The frail group presented significantly greater FAC as well as less lumbar BMD than the robust group (p < 0.05). In the frail group, significant negative relationships were observed between the individual values of FAC with the individual values of BMD (r = -0.35 to -0.43, p < 0.05) and with the individual values of the quadriceps muscle quantity and quality (r = -0.52, p < 0.01), whereas no significant relationships were observed in the robust group. The robust group presented less vascular calcification and more BMD in the vertebral bodies than the frail group. In the frail group, femoral artery calcification was significantly negatively correlated with BMD, leg muscle quality, and muscle mass volume.",
author = "Fernando Idoate and Cadore, {Eduardo L.} and Alvaro Casas-Herrero and Fabricio Zambom-Ferraresi and Nicolas Mart{\'i}nez-Velilla and Leocadio Rodriguez-Ma{\~n}as and Azc{\'a}rate, {Pedro M.} and Martim Bottaro and Robinson Ram{\'i}rez-V{\'e}lez and Mikel Izquierdo",
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Idoate, F, Cadore, EL, Casas-Herrero, A, Zambom-Ferraresi, F, Martínez-Velilla, N, Rodriguez-Mañas, L, Azcárate, PM, Bottaro, M, Ramírez-Vélez, R & Izquierdo, M 2017, 'Noncoronary Vascular Calcification, Bone Mineral Density, and Muscle Mass in Institutionalized Frail Nonagenarians', Rejuvenation Research, vol. 20, n.º 4, pp. 298-308. https://doi.org/10.1089/rej.2016.1868

Noncoronary Vascular Calcification, Bone Mineral Density, and Muscle Mass in Institutionalized Frail Nonagenarians. / Idoate, Fernando; Cadore, Eduardo L.; Casas-Herrero, Alvaro; Zambom-Ferraresi, Fabricio; Martínez-Velilla, Nicolas; Rodriguez-Mañas, Leocadio; Azcárate, Pedro M.; Bottaro, Martim; Ramírez-Vélez, Robinson; Izquierdo, Mikel.

En: Rejuvenation Research, Vol. 20, N.º 4, 01.08.2017, p. 298-308.

Resultado de la investigación: Contribución a RevistaArtículo

TY - JOUR

T1 - Noncoronary Vascular Calcification, Bone Mineral Density, and Muscle Mass in Institutionalized Frail Nonagenarians

AU - Idoate, Fernando

AU - Cadore, Eduardo L.

AU - Casas-Herrero, Alvaro

AU - Zambom-Ferraresi, Fabricio

AU - Martínez-Velilla, Nicolas

AU - Rodriguez-Mañas, Leocadio

AU - Azcárate, Pedro M.

AU - Bottaro, Martim

AU - Ramírez-Vélez, Robinson

AU - Izquierdo, Mikel

PY - 2017/8/1

Y1 - 2017/8/1

N2 - The purpose of this study was to compare the vascular calcification in thoracic aorta (TAC), abdominal aorta (AAC), iliac arteries (IAC), and femoral arteries (FAC) and bone mineral density (BMD) of the lumbar vertebrae between frail and robust nonagenarians, as well as to verify the associations between vascular calcification with BMD, muscle tissue quality, and quantity in both groups. Forty-two elderly subjects participated in this study: 29 institutionalized frail (92.0 ± 3.2 years) and 13 robust (89.0 ± 4.0 years) elderly participants. All patients underwent nonenhanced helical thoracic, abdominal, and thigh computed tomography. The frail group presented significantly greater FAC as well as less lumbar BMD than the robust group (p < 0.05). In the frail group, significant negative relationships were observed between the individual values of FAC with the individual values of BMD (r = -0.35 to -0.43, p < 0.05) and with the individual values of the quadriceps muscle quantity and quality (r = -0.52, p < 0.01), whereas no significant relationships were observed in the robust group. The robust group presented less vascular calcification and more BMD in the vertebral bodies than the frail group. In the frail group, femoral artery calcification was significantly negatively correlated with BMD, leg muscle quality, and muscle mass volume.

AB - The purpose of this study was to compare the vascular calcification in thoracic aorta (TAC), abdominal aorta (AAC), iliac arteries (IAC), and femoral arteries (FAC) and bone mineral density (BMD) of the lumbar vertebrae between frail and robust nonagenarians, as well as to verify the associations between vascular calcification with BMD, muscle tissue quality, and quantity in both groups. Forty-two elderly subjects participated in this study: 29 institutionalized frail (92.0 ± 3.2 years) and 13 robust (89.0 ± 4.0 years) elderly participants. All patients underwent nonenhanced helical thoracic, abdominal, and thigh computed tomography. The frail group presented significantly greater FAC as well as less lumbar BMD than the robust group (p < 0.05). In the frail group, significant negative relationships were observed between the individual values of FAC with the individual values of BMD (r = -0.35 to -0.43, p < 0.05) and with the individual values of the quadriceps muscle quantity and quality (r = -0.52, p < 0.01), whereas no significant relationships were observed in the robust group. The robust group presented less vascular calcification and more BMD in the vertebral bodies than the frail group. In the frail group, femoral artery calcification was significantly negatively correlated with BMD, leg muscle quality, and muscle mass volume.

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Idoate F, Cadore EL, Casas-Herrero A, Zambom-Ferraresi F, Martínez-Velilla N, Rodriguez-Mañas L y otros. Noncoronary Vascular Calcification, Bone Mineral Density, and Muscle Mass in Institutionalized Frail Nonagenarians. Rejuvenation Research. 2017 ago 1;20(4):298-308. https://doi.org/10.1089/rej.2016.1868