Serum levels of dehydroepiandrosterone sulfate (DHEAS) in ocular toxoplasmosis

Alejandra De-la-Torre; Angela Cristina Ríos-Cadavid; Carlos Mario Cardozo-García; Leonardo Padilla; Jorge Enrique Gómez-Marín

doi:10.1016/j.jmii.2011.09.003

Serum levels of dehydroepiandrosterone sulfate (DHEAS) in ocular toxoplasmosis

Título traducido de la contribución: Niveles séricos de sulfato de dehidroepiandrosterona (DHEAS) en la toxoplasmosis ocular

Alejandra De-la-Torre, Angela Cristina Ríos-Cadavid, Carlos Mario Cardozo-García, Leonardo Padilla, Jorge Enrique Gómez-Marín

Resultado de la investigación: Contribución a una revista › Artículo › revisión exhaustiva

3 Citas (Scopus)

Resumen

No hay estudios previos sobre la toxoplasmosis ocular y los niveles séricos de la hormona sulfatada dehidroepiandrosterona (DHEAS). Utilizamos el ensayo de Immulite automatizado por quimioluminiscencia para determinar los niveles de DHEAS. Se estudiaron cuatro grupos: (1) Individuos con infección crónica asintomática con una prueba positiva para IgG anti-Toxoplasma y sin lesiones oculares (n = 16); (2) Pacientes asintomáticos crónicos con cicatrices retinianas de retinocoroiditis por Toxoplasma (n = 19); (3) Pacientes sintomáticos agudos con retinocoroiditis activa por Toxoplasma (n = 26); (4) Individuos con ensayos negativos para IgG anti-Toxoplasma (n = 21). La comparación de los niveles de DHEAS entre los grupos se ajustó por edad y sexo y se aplicaron pruebas estadísticas no paramétricas de Kruskall Wallis. No se encontraron diferencias significativas en los niveles séricos de DHEAS entre los grupos cuando se controlaron la edad y el sexo. Los niveles de DHEAS no fueron significativamente diferentes en la toxoplasmosis ocular activa relacionada con personas no activas o no infectadas.

Título traducido de la contribución	Niveles séricos de sulfato de dehidroepiandrosterona (DHEAS) en la toxoplasmosis ocular
Idioma original	Inglés estadounidense
Páginas (desde-hasta)	65-68
Número de páginas	4
Publicación	Journal of Microbiology, Immunology and Infection
DOI	https://doi.org/10.1016/j.jmii.2011.09.003
Estado	Publicada - feb. 1 2012
Publicado de forma externa	Sí

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title = "Serum levels of dehydroepiandrosterone sulfate (DHEAS) in ocular toxoplasmosis",

abstract = "There are no previous study about ocular toxoplasmosis and serum levels of dehydroepiandrosterone sulphated hormone (DHEAS). We use the chemoluminiscence automatized Immulite assay to determine the levels of DHEAS. Four groups were studied: (1) Individuals with chronic asymptomatic infection with a positive test for IgG anti-Toxoplasma and without ocular lesions (n = 16); (2) Chronic asymptomatic patients with retinal scars of retinochoroiditis by Toxoplasma (n = 19); (3) Acute symptomatic patients with active retinochoroiditis by Toxoplasma (n = 26); (4) Individuals with negative assays for IgG anti-Toxoplasma (n = 21). Comparison of DHEAS levels between groups were adjusted by age and sex and non-parametric Kruskall Wallis statistical tests were applied. No significant differences in serum levels of DHEAS were found between groups when age and sex were controlled. DHEAS levels were not significantly different in active ocular toxoplasmosis related to non active or non infected persons. {\textcopyright} 2011.",

author = "Alejandra De-la-Torre and R{\'i}os-Cadavid, {Angela Cristina} and Cardozo-Garc{\'i}a, {Carlos Mario} and Leonardo Padilla and G{\'o}mez-Mar{\'i}n, {Jorge Enrique}",

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doi = "10.1016/j.jmii.2011.09.003",

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T1 - Serum levels of dehydroepiandrosterone sulfate (DHEAS) in ocular toxoplasmosis

AU - De-la-Torre, Alejandra

AU - Ríos-Cadavid, Angela Cristina

AU - Cardozo-García, Carlos Mario

AU - Padilla, Leonardo

AU - Gómez-Marín, Jorge Enrique

PY - 2012/2/1

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N2 - There are no previous study about ocular toxoplasmosis and serum levels of dehydroepiandrosterone sulphated hormone (DHEAS). We use the chemoluminiscence automatized Immulite assay to determine the levels of DHEAS. Four groups were studied: (1) Individuals with chronic asymptomatic infection with a positive test for IgG anti-Toxoplasma and without ocular lesions (n = 16); (2) Chronic asymptomatic patients with retinal scars of retinochoroiditis by Toxoplasma (n = 19); (3) Acute symptomatic patients with active retinochoroiditis by Toxoplasma (n = 26); (4) Individuals with negative assays for IgG anti-Toxoplasma (n = 21). Comparison of DHEAS levels between groups were adjusted by age and sex and non-parametric Kruskall Wallis statistical tests were applied. No significant differences in serum levels of DHEAS were found between groups when age and sex were controlled. DHEAS levels were not significantly different in active ocular toxoplasmosis related to non active or non infected persons. © 2011.

AB - There are no previous study about ocular toxoplasmosis and serum levels of dehydroepiandrosterone sulphated hormone (DHEAS). We use the chemoluminiscence automatized Immulite assay to determine the levels of DHEAS. Four groups were studied: (1) Individuals with chronic asymptomatic infection with a positive test for IgG anti-Toxoplasma and without ocular lesions (n = 16); (2) Chronic asymptomatic patients with retinal scars of retinochoroiditis by Toxoplasma (n = 19); (3) Acute symptomatic patients with active retinochoroiditis by Toxoplasma (n = 26); (4) Individuals with negative assays for IgG anti-Toxoplasma (n = 21). Comparison of DHEAS levels between groups were adjusted by age and sex and non-parametric Kruskall Wallis statistical tests were applied. No significant differences in serum levels of DHEAS were found between groups when age and sex were controlled. DHEAS levels were not significantly different in active ocular toxoplasmosis related to non active or non infected persons. © 2011.

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DO - 10.1016/j.jmii.2011.09.003

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JO - Journal of Microbiology, Immunology and Infection

JF - Journal of Microbiology, Immunology and Infection

ER -

Serum levels of dehydroepiandrosterone sulfate (DHEAS) in ocular toxoplasmosis

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