TY - JOUR
T1 - New 2030 Global Targets for Histoplasmosis from International Society for Human and Animal Mycology (ISHAM) 2025 Histoplasmosis Working Group
AU - Pasqualotto, Alessandro C.
AU - Denning, David W.
AU - Le, Thuy
AU - Govender, Nelesh P.
AU - Hagen, Ferry
AU - Zancope-Oliveira, Rosely M.
AU - Caceres, Diego H.
AU - Francoise, Ugo
AU - Guimaraes, Allan
AU - Damasceno, Lisandra S.
AU - Falci, Diego R.
AU - Gomez, Beatriz L.
AU - Schwartz, Ilan
AU - Vidal, Jose E.
AU - Galan, Luis E.
AU - Xavier, Melissa O.
AU - Nacher, Mathieu
AU - Effron, Guillermo G.
AU - Brown, Gordon
AU - Barros, Nicolas
AU - Godoy, Cassia M.
AU - Fraga, Taiguara
AU - Soares, Renata B.A.
AU - Severo, Cecilia B.
AU - Schwarzbold, Alexandre V.
AU - Berrio, Indira
AU - de Melo, Marineide G.
AU - Reis, Nicole
AU - Tenorio, Bernardo G.
AU - Leitao, Terezinha M.J.
AU - Claudilson, Claudilson J.
AU - Bay, Monica B.
AU - de Lacerda, Marcus V.G.
AU - Bazana, Luana C.G.
AU - Dalla Lana, Daiane F.
AU - Vieceli, Tarsila
AU - Riche, Cezar V.W.
AU - Arathoon, Eduardo
AU - Canteros, Cristina
AU - Boulware, David
AU - Alastruey-Izquierdo, Ana
AU - Oladele, Rita
AU - de M. Teixeira, Marcus
AU - Colombo, Arnaldo L.
AU - Perez, Freddy M.
AU - Chiller, Tom
AU - Bahr, Nathan C.
AU - Tudela, Juan L.R.
AU - Adenis, Antoine
N1 - Publisher Copyright:
© 2026, Centers for Disease Control and Prevention (CDC). All rights reserved.
PY - 2026/3
Y1 - 2026/3
N2 - Histoplasmosis remains a neglected yet deadly fungal infection, disproportionately affecting persons living with HIV/AIDS and other immunocompromised populations in endemic regions. Despite the World Health Organization's designation of Histoplasma as a high-priority pathogen, the disease remains underdiagnosed and excluded from national surveillance systems, resulting in delayed treatment and high death rates. To coordinate a global response, the International Society for Human and Animal Mycology convened a Histoplasmosis Working Group during its 2025 congress in Brazil. Experts engaged in structured discussions across 5 domains: awareness, research, diagnostics and treatment, capacity building, and fungal biology. The group highlighted persistent diagnostic delays, underuse of antigen testing, and poor access to liposomal amphotericin B and itraconazole. Innovations such as lateral flow assays and molecular tools were discussed, alongside the need for biobanks and validated diagnostic algorithms. A global 90–90–90 target for histoplasmosis by 2030 was proposed to improve diagnosis, treatment, and survival.
AB - Histoplasmosis remains a neglected yet deadly fungal infection, disproportionately affecting persons living with HIV/AIDS and other immunocompromised populations in endemic regions. Despite the World Health Organization's designation of Histoplasma as a high-priority pathogen, the disease remains underdiagnosed and excluded from national surveillance systems, resulting in delayed treatment and high death rates. To coordinate a global response, the International Society for Human and Animal Mycology convened a Histoplasmosis Working Group during its 2025 congress in Brazil. Experts engaged in structured discussions across 5 domains: awareness, research, diagnostics and treatment, capacity building, and fungal biology. The group highlighted persistent diagnostic delays, underuse of antigen testing, and poor access to liposomal amphotericin B and itraconazole. Innovations such as lateral flow assays and molecular tools were discussed, alongside the need for biobanks and validated diagnostic algorithms. A global 90–90–90 target for histoplasmosis by 2030 was proposed to improve diagnosis, treatment, and survival.
UR - https://www.scopus.com/pages/publications/105033650820
UR - https://www.scopus.com/pages/publications/105033650820#tab=citedBy
U2 - 10.3201/eid3203.251165
DO - 10.3201/eid3203.251165
M3 - Research Article
C2 - 41863768
AN - SCOPUS:105033650820
SN - 1080-6040
VL - 32
SP - e1-e9
JO - Emerging Infectious Diseases
JF - Emerging Infectious Diseases
IS - 3
ER -
ODS 3: Salud y bienestar