Multiple drugs interaction

Carlos Alberto Calderon Ospina

Multiple drugs interaction

Carlos Alberto Calderon Ospina

Producción científica: Contribución a revista › Artículo de Investigación › revisión exhaustiva

Resumen

A 58-year-old man developed neurological toxicity during
concomitant administration of phenytoin, atorvastatin,
enalapril and metformin [routes not stated].
The man, who had been receiving phenytoin
100 mg/12 hours capsule for last two months for epilepsy,
presented for confusion, double vision, in-coordination and
difficulty articulating words. A total phenytoin plasma
concentration was high 49 mg/L. He was also receiving
enalapril 20mg twice daily for arterial hypertension, metformin
850mg twice daily for diabetes mellitus and atorvastatin 20mg
once daily and aspirin for prevention of heart attack.
Phenytoin-induced neurotoxicity was suspected.

Idioma original	Inglés
Número de artículo	1711
Publicación	Reactions
Volumen	209
N.º	2018
Estado	Publicada - jul. 21 2018

Acceder al documento

https://link.springer.com/article/10.1007/s40278-018-49190-4

Citar esto

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title = "Multiple drugs interaction",

abstract = "A 58-year-old man developed neurological toxicity during concomitant administration of phenytoin, atorvastatin, enalapril and metformin [routes not stated]. The man, who had been receiving phenytoin 100 mg/12 hours capsule for last two months for epilepsy, presented for confusion, double vision, in-coordination and difficulty articulating words. A total phenytoin plasma concentration was high 49 mg/L. He was also receiving enalapril 20mg twice daily for arterial hypertension, metformin 850mg twice daily for diabetes mellitus and atorvastatin 20mg once daily and aspirin for prevention of heart attack. Phenytoin-induced neurotoxicity was suspected.",

author = "\{Calderon Ospina\}, \{Carlos Alberto\}",

year = "2018",

month = jul,

day = "21",

language = "Ingl{\'e}s",

volume = "209 ",

number = "2018",

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TY - JOUR

T1 - Multiple drugs interaction

AU - Calderon Ospina, Carlos Alberto

PY - 2018/7/21

Y1 - 2018/7/21

N2 - A 58-year-old man developed neurological toxicity during concomitant administration of phenytoin, atorvastatin, enalapril and metformin [routes not stated]. The man, who had been receiving phenytoin 100 mg/12 hours capsule for last two months for epilepsy, presented for confusion, double vision, in-coordination and difficulty articulating words. A total phenytoin plasma concentration was high 49 mg/L. He was also receiving enalapril 20mg twice daily for arterial hypertension, metformin 850mg twice daily for diabetes mellitus and atorvastatin 20mg once daily and aspirin for prevention of heart attack. Phenytoin-induced neurotoxicity was suspected.

AB - A 58-year-old man developed neurological toxicity during concomitant administration of phenytoin, atorvastatin, enalapril and metformin [routes not stated]. The man, who had been receiving phenytoin 100 mg/12 hours capsule for last two months for epilepsy, presented for confusion, double vision, in-coordination and difficulty articulating words. A total phenytoin plasma concentration was high 49 mg/L. He was also receiving enalapril 20mg twice daily for arterial hypertension, metformin 850mg twice daily for diabetes mellitus and atorvastatin 20mg once daily and aspirin for prevention of heart attack. Phenytoin-induced neurotoxicity was suspected.

M3 - Artículo de Investigación

VL - 209

JO - Reactions

JF - Reactions

IS - 2018

M1 - 1711

ER -