Diagnostic moléculaire des papillomavirus humains (HPV) : quel(s) test(s) en pratique clinique ?

D. Guenat, D. Riethmuller, R. Ramanah, A. Morel, F. Aubin, C. Mougin, J. L. Prétet

Resultado de la investigación: Contribución a una revistaArtículo de revisiónrevisión exhaustiva


Prescription of an HPV test in practice will enable the clinician to optimize the monitoring and the management of patients, especially in the context of cervical cancer screening. Numerous HPV tests are available that present different analytical and clinical sensitivity and specificity. International recommendations on clinical performance of HPV tests used for cervical cancer screening have been published by a group of experts, and tests that meet these performance criteria should be used. Apart from the HPV detection kit, the whole circuit from sampling to report of the results must be considered. This implies that the pre-analytical (sampling, quality of sample collection medium, storage condition and sample transportation…) and post-analytical steps (quality of result reporting, providing expert advices…) are also standardized. For this purpose, medical-biology laboratories are subjected to a COFRAC certification, as defined by the international standard ISO 15189 providing quality criteria for any clinical laboratory test and HPV test in particular.

Título traducido de la contribuciónMolecular diagnosis of human papillomaviruses (HPV): What test(s) in clinical practice?
Idioma originalFrancés
Páginas (desde-hasta)1009-1019
Número de páginas11
PublicaciónJournal de Gynecologie Obstetrique et Biologie de la Reproduction
EstadoPublicada - nov 1 2016
Publicado de forma externa

All Science Journal Classification (ASJC) codes

  • Medicina reproductiva
  • Ginecología y obstetricia


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