Mayaro: an emerging viral threat?

Resultado de la investigación: Contribución a una revistaArtículo de revisiónrevisión exhaustiva

50 Citas (Scopus)

Resumen

Mayaro virus (MAYV), an enveloped RNA virus, belongs to the Togaviridae family and Alphavirus genus. This arthropod-borne virus (Arbovirus) is similar to Chikungunya (CHIKV), Dengue (DENV), and Zika virus (ZIKV). The term “ChikDenMaZika syndrome” has been coined for clinically suspected arboviruses, which have arisen as a consequence of the high viral burden, viral co-infection, and co-circulation in South America. In most cases, MAYV disease is nonspecific, mild, and self-limited. Fever, arthralgia, and maculopapular rash are among the most common symptoms described, being largely indistinguishable from those caused by other arboviruses. However, severe manifestations of the infection have been reported, such as chronic polyarthritis, neurological complications, hemorrhage, myocarditis, and even death. Currently, there are no specific commercial tools for the diagnosis of MAYV, and the use of serological methods can be affected by cross-reactivity and the window period. A diagnosis based on clinical and epidemiological data alone is still premature. Therefore, new entomological research is warranted, and new highly specific molecular diagnostic methods should be developed. This comprehensive review is intended to encourage public health authorities and scientific communities to actively work on diagnosing, preventing, and treating MAYV infection.

Idioma originalInglés estadounidense
Número de artículo163
PublicaciónEmerging Microbes and Infections
Volumen7
N.º1
DOI
EstadoPublicada - dic 1 2018

All Science Journal Classification (ASJC) codes

  • Parasitología
  • Epidemiología
  • Microbiología
  • Inmunología
  • Descubrimiento de medicamentos
  • Virología
  • Enfermedades infecciosas

Huella

Profundice en los temas de investigación de 'Mayaro: an emerging viral threat?'. En conjunto forman una huella única.

Citar esto