TY - JOUR
T1 - Lupus mimickers
AU - Calixto, Omar Javier
AU - Franco, Juan Sebastian
AU - Anaya, Juan Manuel
N1 - Funding Information:
The authors are grateful to all the members of the Center for Autoimmune Diseases Research (CREA) for their fruitful discussions and contributions to this paper. This work was supported by The School of Medicine and Health Sciences of Universidad del Rosario (ABN011) in Bogotá, Colombia.
Copyright:
Copyright 2014 Elsevier B.V., All rights reserved.
PY - 2014/8
Y1 - 2014/8
N2 - Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by multisystem organ involvement, heterogeneity of clinical features, and variety in degree of severity. The differential diagnosis is a crucial aspect in SLE as many other autoimmune diseases portray clinical similarities and autoantibody positivity. Lupus mimickers refer to a group of conditions that exhibit both clinical features and laboratory characteristics, including autoantibody profiles that resemble those present in patients with SLE, and prompt a diagnostic challenge in everyday clinical practice. Thus, lupus mimickers may present as a lupus-like condition (i.e., 2 or 3 criteria) or as one meeting the classification criteria for SLE. Herein we review and classify the current literature on lupus mimickers based on diverse etiologies which include infections, malign and benign neoplasms, medications, and vaccine-related reactions.
AB - Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by multisystem organ involvement, heterogeneity of clinical features, and variety in degree of severity. The differential diagnosis is a crucial aspect in SLE as many other autoimmune diseases portray clinical similarities and autoantibody positivity. Lupus mimickers refer to a group of conditions that exhibit both clinical features and laboratory characteristics, including autoantibody profiles that resemble those present in patients with SLE, and prompt a diagnostic challenge in everyday clinical practice. Thus, lupus mimickers may present as a lupus-like condition (i.e., 2 or 3 criteria) or as one meeting the classification criteria for SLE. Herein we review and classify the current literature on lupus mimickers based on diverse etiologies which include infections, malign and benign neoplasms, medications, and vaccine-related reactions.
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U2 - 10.1016/j.autrev.2014.05.002
DO - 10.1016/j.autrev.2014.05.002
M3 - Review article
C2 - 24820523
AN - SCOPUS:84902126572
SN - 1568-9972
VL - 13
SP - 865
EP - 872
JO - Autoimmunity Reviews
JF - Autoimmunity Reviews
IS - 8
ER -
