LDH-A and α-actin as tools to assess the effects of temperature on the vertebrate genome: Some problems

Oliver Clay, Stilianos Arhondakis, Giuseppe D'Onofrio, Giorgio Bernardi

Resultado de la investigación: Contribución a una revistaArtículorevisión exhaustiva

4 Citas (Scopus)

Resumen

In a recent paper written with the purpose of shedding light on the question of whether genomic GC levels are related to temperature in vertebrates, Ream et al. [Mol. Biol. Evol. 20 (2003) 105] offered an analysis of two sets of homologous genes: those coding for α-actin and lactate dehydrogenase-A (LDH-A). The conclusion was that "there is no consistent relationship between adaptation temperature and the percentage of thermal stability-enhancing G+C base pairs in protein-coding genes". We argue here that the data presented neither prove nor suggest such a conclusion because of conceptual and methodological errors.

Idioma originalInglés estadounidense
Páginas (desde-hasta)157-160
Número de páginas4
PublicaciónGene
Volumen317
N.º1-2
DOI
EstadoPublicada - oct 23 2003
Publicado de forma externa

All Science Journal Classification (ASJC) codes

  • Genética

Huella

Profundice en los temas de investigación de 'LDH-A and α-actin as tools to assess the effects of temperature on the vertebrate genome: Some problems'. En conjunto forman una huella única.

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