Arterial Stiffness is Reduced Regardless of Ecercise Training in Obese Paediatric Populations: A Meta-analysis of Randomised Controlled Trials

Título traducido de la contribución: La rigidez arterial se reduce independientemente del entrenamiento de la eccercosis en poblaciones pediátricas obesas: un metanálisis de ensayos controlados aleatorios

Robinson Ramírez-Vélez, Maria Alejandra Tordecilla Sanders, Antonio Garcia-Hermoso, Katherine González-Ruíz

Resultado de la investigación: Contribución a RevistaArtículo

Resumen

PROPÓSITO: En las poblaciones pediátricas, ha aumentado el uso del grosor de la íntima-media carotídea (IMT) como marcador del riesgo cardiovascular. Sin embargo, los estudios anteriores que examinaron los efectos del entrenamiento con ejercicios sobre la estructura y función arterial en niños y adolescentes obesos han mostrado resultados inconsistentes. El objetivo principal de esta revisión sistemática y metanálisis es ampliar el cuerpo actual de la bibliografía proporcionando una estimación cuantitativa del cambio en la TMI carotídea después del entrenamiento con ejercicios, así como proporcionar un análisis exploratorio de los moderadores potenciales asociados con la variación en respuesta a una intervención de entrenamiento con ejercicios en jóvenes con sobrepeso y obesos.
MÉTODOS: Se realizó una búsqueda de la bibliografía mediante las bases de datos electrónicas CENTRAL, EMBASE y MEDLINE. Los términos utilizados fueron: ['Obesidad' y 'Sobrepeso' O], ['Ejercicio' y 'Entrenamiento' y 'Actividad física' y 'Deporte' O]. Todos los términos de los encabezamientos de los temas médicos se combinaron con el grosor del intima-media* y los niños y adolescentes como limitadores. No se exploraron los estudios informados en idiomas diferentes al inglés. El análisis se limitó a los estudios que examinaron el efecto de las intervenciones con ejercicios sobre la IMT carotídea en la obesidad pediátrica (6-18 años de edad). Se incluyeron seis ensayos controlados aleatorios (ECA) (303 jóvenes). Se calcularon los intervalos de confianza del 95%.
RESULTADOS: El ejercicio se asoció con una reducción pequeña a moderada pero significativa de la IMT carotídea (g = 0,306; IC del 95%: -0,540 a -0,072; p = 0,011). Asimismo, la duración del programa de ejercicio por semana influyó significativamente en el efecto del ejercicio sobre la IMT carotídea (β=-0.060; p=0.015). El análisis de metarregresión muestra que hubo una mayor disminución de la IMT carotídea en los estudios con una duración de más de una semana. El coeficiente de regresión de la pendiente fue -0,060[IC del 95%: -0,136 a -0,015] y fue significativo (p = 0,015). Estos datos indican que se observó una mayor disminución de la IMT carotídea en los individuos que lograron intervenciones más grandes en términos de minutos por semana.
CONCLUSIONES: El ejercicio parece reducir la IMT carotídea en la obesidad infantil. Por lo tanto, animar a las personas obesas pediátricas a ser físicamente activas puede llevar a cambios favorables en la pared arterial.
Idioma originalEnglish (US)
Páginas (desde-hasta)806
Número de páginas1
PublicaciónMedicine and Science in Sports and Exercise
Volumen49
N.º5
EstadoPublished - 2017

Huella dactilar

Vascular Stiffness
Carotid Intima-Media Thickness
Meta-Analysis
Randomized Controlled Trials
Exercise
Pediatrics
Population
Pediatric Obesity
Medical Subject Headings
MEDLINE
Sports
Teaching
Language
Obesity
Regression Analysis
Databases
Confidence Intervals

Citar esto

@article{c76af2bab7084c3398db371335c850f3,
title = "Arterial Stiffness is Reduced Regardless of Ecercise Training in Obese Paediatric Populations: A Meta-analysis of Randomised Controlled Trials",
abstract = "PURPOSE: In paediatric populations, the use of carotid intima-media thickness (IMT) as a marker of cardiovascular risk has increased. However, previous studies examining the effects of exercise training on arterial structure and function in obese children and adolescents have shown inconsistent findings. The primary aim of this systematic review and meta-analysis is to expand on the current body of literature by providing a quantitative estimate of the change in carotid IMT following exercise training, as well as to provide an exploratory analysis of potential moderators associated with the variation in response to an exercise training intervention in overweight and obese youth.METHODS: A search of the literature was performed using the electronic databases CENTRAL, EMBASE, and MEDLINE. The terms used were: [‘Obesity’ and ‘Overweight’ OR], [‘Exercise’ and ‘Training’ and ‘physical activity’ and ‘sport’ OR]. All medical subject heading terms were combined with intima-media thickness* and children and adolescent as limiters. Studies reported in languages other than English were not explored. The analysis was restricted to studies that examined the effect of exercise interventions on carotid IMT in paediatric obesity (6-18-year-olds). Six randomised controlled trials (RCTs) (303 youths) were included. Hedges´g and 95{\%} confidence intervals were calculated.RESULTS: Exercise was associated with a small-to-moderate but significant reduction in carotid IMT (g=−0.306; 95{\%} CI, −0.540 to −0.072; p=0.011). Likewise, exercise programme duration per week significantly influenced the effect of exercise on carotid IMT (β=-0.060; p=0.015). The meta-regression analysis shows that there was a greater decrease in carotid IMT in studies with a duration of more than a week. The slope regression coefficient was -0.060 [95{\%} CI = -0.136 to -0.015] and was significant (p=0.015). These data indicate that greater decrease in carotid IMT was observed in individuals that achieved larger interventions in terms of minutes per week.CONCLUSIONS: Exercise seems to reduce carotid IMT in childhood obesity. Therefore, encouraging obese paediatric individuals to become physically active can lead to favourable changes in the arterial wall.",
author = "Robinson Ram{\'i}rez-V{\'e}lez and {Tordecilla Sanders}, {Maria Alejandra} and Antonio Garcia-Hermoso and Katherine Gonz{\'a}lez-Ru{\'i}z",
year = "2017",
language = "English (US)",
volume = "49",
pages = "806",
journal = "Medicine and Science in Sports and Exercise",
issn = "0195-9131",
publisher = "Lippincott Williams and Wilkins",
number = "5",

}

Arterial Stiffness is Reduced Regardless of Ecercise Training in Obese Paediatric Populations: A Meta-analysis of Randomised Controlled Trials. / Ramírez-Vélez, Robinson; Tordecilla Sanders, Maria Alejandra; Garcia-Hermoso, Antonio; González-Ruíz, Katherine.

En: Medicine and Science in Sports and Exercise, Vol. 49, N.º 5, 2017, p. 806.

Resultado de la investigación: Contribución a RevistaArtículo

TY - JOUR

T1 - Arterial Stiffness is Reduced Regardless of Ecercise Training in Obese Paediatric Populations: A Meta-analysis of Randomised Controlled Trials

AU - Ramírez-Vélez, Robinson

AU - Tordecilla Sanders, Maria Alejandra

AU - Garcia-Hermoso, Antonio

AU - González-Ruíz, Katherine

PY - 2017

Y1 - 2017

N2 - PURPOSE: In paediatric populations, the use of carotid intima-media thickness (IMT) as a marker of cardiovascular risk has increased. However, previous studies examining the effects of exercise training on arterial structure and function in obese children and adolescents have shown inconsistent findings. The primary aim of this systematic review and meta-analysis is to expand on the current body of literature by providing a quantitative estimate of the change in carotid IMT following exercise training, as well as to provide an exploratory analysis of potential moderators associated with the variation in response to an exercise training intervention in overweight and obese youth.METHODS: A search of the literature was performed using the electronic databases CENTRAL, EMBASE, and MEDLINE. The terms used were: [‘Obesity’ and ‘Overweight’ OR], [‘Exercise’ and ‘Training’ and ‘physical activity’ and ‘sport’ OR]. All medical subject heading terms were combined with intima-media thickness* and children and adolescent as limiters. Studies reported in languages other than English were not explored. The analysis was restricted to studies that examined the effect of exercise interventions on carotid IMT in paediatric obesity (6-18-year-olds). Six randomised controlled trials (RCTs) (303 youths) were included. Hedges´g and 95% confidence intervals were calculated.RESULTS: Exercise was associated with a small-to-moderate but significant reduction in carotid IMT (g=−0.306; 95% CI, −0.540 to −0.072; p=0.011). Likewise, exercise programme duration per week significantly influenced the effect of exercise on carotid IMT (β=-0.060; p=0.015). The meta-regression analysis shows that there was a greater decrease in carotid IMT in studies with a duration of more than a week. The slope regression coefficient was -0.060 [95% CI = -0.136 to -0.015] and was significant (p=0.015). These data indicate that greater decrease in carotid IMT was observed in individuals that achieved larger interventions in terms of minutes per week.CONCLUSIONS: Exercise seems to reduce carotid IMT in childhood obesity. Therefore, encouraging obese paediatric individuals to become physically active can lead to favourable changes in the arterial wall.

AB - PURPOSE: In paediatric populations, the use of carotid intima-media thickness (IMT) as a marker of cardiovascular risk has increased. However, previous studies examining the effects of exercise training on arterial structure and function in obese children and adolescents have shown inconsistent findings. The primary aim of this systematic review and meta-analysis is to expand on the current body of literature by providing a quantitative estimate of the change in carotid IMT following exercise training, as well as to provide an exploratory analysis of potential moderators associated with the variation in response to an exercise training intervention in overweight and obese youth.METHODS: A search of the literature was performed using the electronic databases CENTRAL, EMBASE, and MEDLINE. The terms used were: [‘Obesity’ and ‘Overweight’ OR], [‘Exercise’ and ‘Training’ and ‘physical activity’ and ‘sport’ OR]. All medical subject heading terms were combined with intima-media thickness* and children and adolescent as limiters. Studies reported in languages other than English were not explored. The analysis was restricted to studies that examined the effect of exercise interventions on carotid IMT in paediatric obesity (6-18-year-olds). Six randomised controlled trials (RCTs) (303 youths) were included. Hedges´g and 95% confidence intervals were calculated.RESULTS: Exercise was associated with a small-to-moderate but significant reduction in carotid IMT (g=−0.306; 95% CI, −0.540 to −0.072; p=0.011). Likewise, exercise programme duration per week significantly influenced the effect of exercise on carotid IMT (β=-0.060; p=0.015). The meta-regression analysis shows that there was a greater decrease in carotid IMT in studies with a duration of more than a week. The slope regression coefficient was -0.060 [95% CI = -0.136 to -0.015] and was significant (p=0.015). These data indicate that greater decrease in carotid IMT was observed in individuals that achieved larger interventions in terms of minutes per week.CONCLUSIONS: Exercise seems to reduce carotid IMT in childhood obesity. Therefore, encouraging obese paediatric individuals to become physically active can lead to favourable changes in the arterial wall.

M3 - Article

VL - 49

SP - 806

JO - Medicine and Science in Sports and Exercise

JF - Medicine and Science in Sports and Exercise

SN - 0195-9131

IS - 5

ER -