Is It Possible to Correlate Age Related Time-Dependent Micro Mechanical Properties of Cortical Bone and Its Physico-Chemical Data?

Sebastián Jaramillo-Isaza, Pierre Emmanuel Mazeran, Karim El-Kirat, Marie Christine Ho Ba Tho

Producción científica: Capítulo en Libro/InformeContribución a la conferencia

Resumen

Correlational models between mechanical and physico-chemical properties are of interest for bone modeling and numerical simulations of bone growth and remodeling. Therefore, the aim of this work was to determine if it is possible to correlate mechanical and physic-chemical properties of cortical bone. Micro-mechanical and physico-chemical data were assessed in a rat cortical bone life-span model including samples aged of 1, 4, 9, 12, 18 and 24 months old. Time-dependent mechanical properties at the micro scale including elasticity, viscous properties and hardness were determined using nanoindentation tests. Meanwhile, physico-chemical properties include tissue micro-porosity, mineral, phosphates, carbonates and collagen content were determined using specific techniques for each property. Then, both properties were correlated and the highest matched were used to propose correlational models using multivariable-linear regressions. These initial results show good determinant and correlation coefficients in high agreement with the experimental data. These results could provide new evidences of how physico-chemical properties affect the mechanical response of bone material.

Idioma originalInglés estadounidense
Título de la publicación alojadaApplied Computer Sciences in Engineering - 6th Workshop on Engineering Applications, WEA 2019, Proceedings
EditoresJuan Carlos Figueroa-García, Mario Duarte-González, Sebastián Jaramillo-Isaza, Alvaro David Orjuela-Cañon, Yesid Díaz-Gutierrez
EditorialSpringer
Páginas345-356
Número de páginas12
ISBN (versión impresa)9783030310189
DOI
EstadoPublicada - 2019
Publicado de forma externa
Evento6th Workshop on Engineering Applications, WEA 2019 - Santa Marta, Colombia
Duración: oct. 16 2019oct. 18 2019

Serie de la publicación

NombreCommunications in Computer and Information Science
Volumen1052
ISSN (versión impresa)1865-0929
ISSN (versión digital)1865-0937

Conferencia

Conferencia6th Workshop on Engineering Applications, WEA 2019
País/TerritorioColombia
CiudadSanta Marta
Período10/16/1910/18/19

Áreas temáticas de ASJC Scopus

  • Ciencia de la Computación General
  • Matemáticas General

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