Imaging-Based Anatomical Characterization of Aortic Aneurysms and Dissections: An Observational Study in a Tertiary Hospital in Bogotá, Colombia

Angy Carolina Villamil Duarte; Ernesto Fajardo Chavarro; Adriana Urbina; Juan Fernando Cediel Becerra; Sergio Borda; María Paula Cerón Falla; María Andrea Calderón Ardila; Jorge Alberto Carrillo Bayona

doi:10.3390/medicina61091558

Imaging-Based Anatomical Characterization of Aortic Aneurysms and Dissections: An Observational Study in a Tertiary Hospital in Bogotá, Colombia

Título traducido de la contribución: Caracterización anatómica basada en imágenes de aneurismas y disecciones aórticas: Un estudio observacional en un hospital terciario de Bogotá, Colombia

Angy Carolina Villamil Duarte
, Ernesto Fajardo Chavarro
, Adriana Urbina
, Juan Fernando Cediel Becerra
, Sergio Borda
, María Paula Cerón Falla
, María Andrea Calderón Ardila
, Jorge Alberto Carrillo Bayona

Producción científica: Contribución a revista › Artículo de Investigación › revisión exhaustiva

Resumen

Antecedentes y objetivos: Los aneurismas y disecciones aórticas son trastornos vasculares potencialmente mortales con alta morbilidad y mortalidad. Mejorar las estrategias diagnósticas y terapéuticas requiere una caracterización precisa de sus características anatómicas y clínicas. Este estudio tuvo como objetivo detallar las características anatómicas demográficas, clínicas y de imagen de los aneurismas y disecciones aórticas en una cohorte de pacientes colombianos. Materiales y métodos: Realizamos un estudio observacional, descriptivo y retrospectivo en un hospital terciario en Bogotá, Colombia. Se incluyeron pacientes adultos (≥18 años) con aneurisma o disección aórtica confirmada radiológicamente en angiografía por tomografía computarizada (ATC) entre 2010 y 2021. Se extrajeron datos demográficos, clínicos y morfológicos. Las asociaciones se exploraron mediante pruebas de chi-cuadrado y U de Mann-Whitney. Se aplicó regresión logística multivariante para identificar predictores independientes de mortalidad hospitalaria. Resultados: Este estudio incluyó 539 pacientes (edad media: 69,3 ± 11,5 años; 53,6% varones). Los aneurismas de aorta abdominal infrarrenales fueron los más frecuentes (63,7%), con morfología fusiforme observada en el 92% de los casos. Los aneurismas saculares fueron significativamente más comunes en mujeres ( p = 0,0267) y en segmentos no infrarrenales ( p = 0,0162). Entre los pacientes con aneurismas, el diámetro aórtico fue un predictor independiente de mortalidad (OR = 1,03; IC del 95%: 1,01-1,05; p < 0,001). Ninguna variable individual predijo significativamente la mortalidad en casos de disección. Conclusiones: En esta cohorte, predominan la localización infrarrenal y la forma fusiforme. Los patrones morfológicos se asociaron con el sexo y la distribución anatómica. Aunque se observaron tendencias, no se identificaron predictores estadísticamente significativos de muerte en casos de disección. Estos hallazgos resaltan el valor de la detección temprana y el tratamiento personalizado y refuerzan la importancia de generar datos específicos de cada región para fundamentar la toma de decisiones clínicas en entornos latinoamericanos.

Título traducido de la contribución	Caracterización anatómica basada en imágenes de aneurismas y disecciones aórticas: Un estudio observacional en un hospital terciario de Bogotá, Colombia
Idioma original	Inglés estadounidense
Número de artículo	1558
Publicación	Medicina
Volumen	61
N.º	9
DOI	https://doi.org/10.3390/medicina61091558
Estado	Publicada - sept 2025

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ODS 3: Salud y bienestar

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@article{45de043f32094c549b00c7c7330b5ecb,

title = "Imaging-Based Anatomical Characterization of Aortic Aneurysms and Dissections: An Observational Study in a Tertiary Hospital in Bogot{\'a}, Colombia",

abstract = "Background and Objectives: Aortic aneurysms and dissections are life-threatening vascular disorders with high morbidity and mortality. Enhancing diagnostic and therapeutic strategies requires a precise characterization of their anatomical and clinical features. This study aimed to detail the demographic, clinical, and imaging-based anatomical characteristics of aortic aneurysms and dissections in a cohort of Colombian patients. Materials and Methods: We conducted a retrospective, descriptive, observational study at a tertiary hospital in Bogot{\'a}, Colombia. Adult patients (≥18 years) with radiologically confirmed aortic aneurysm or dissection on computed tomography angiography (CTA) between 2010 and 2021 were included. Demographic, clinical, and morphological data were extracted. Associations were explored using chi-squared and Mann{\textendash}Whitney U tests. Multivariate logistic regression was applied to identify independent predictors of in-hospital mortality. Results: This study included 539 patients (mean age: 69.3 ± 11.5 years; 53.6\% male). Infrarenal abdominal aortic aneurysms were the most frequent (63.7\%), with fusiform morphology observed in 92\% of cases. Saccular aneurysms were significantly more common in females (p = 0.0267) and in non-infrarenal segments (p = 0.0162). Among patients with aneurysms, aortic diameter was an independent predictor of mortality (OR = 1.03; 95\% CI: 1.01{\textendash}1.05; p < 0.001). No individual variable significantly predicted mortality in dissection cases. Conclusions: In this cohort, infrarenal location and fusiform shape predominate. Morphological patterns were associated with sex and anatomical distribution. Although trends were observed, no statistically significant predictors of death were identified in dissection cases. These findings highlight the value of early detection and tailored management and reinforce the importance of generating region-specific data to inform clinical decision making in Latin American settings.",

author = "Duarte, \{Angy Carolina Villamil\} and Chavarro, \{Ernesto Fajardo\} and Adriana Urbina and Becerra, \{Juan Fernando Cediel\} and Sergio Borda and Falla, \{Mar{\'i}a Paula Cer{\'o}n\} and Ardila, \{Mar{\'i}a Andrea Calder{\'o}n\} and Bayona, \{Jorge Alberto Carrillo\}",

note = "Publisher Copyright: {\textcopyright} 2025 by the authors.",

year = "2025",

month = sep,

doi = "10.3390/medicina61091558",

language = "English (US)",

volume = "61",

journal = "Medicina",

issn = "1010-660X",

publisher = "Multidisciplinary Digital Publishing Institute (MDPI)",

number = "9",

}

Imaging-Based Anatomical Characterization of Aortic Aneurysms and Dissections: An Observational Study in a Tertiary Hospital in Bogotá, Colombia. / Duarte, Angy Carolina Villamil; Chavarro, Ernesto Fajardo; Urbina, Adriana et al.
En: Medicina, Vol. 61, N.º 9, 1558, 09.2025.

Producción científica: Contribución a revista › Artículo de Investigación › revisión exhaustiva

TY - JOUR

T1 - Imaging-Based Anatomical Characterization of Aortic Aneurysms and Dissections

T2 - An Observational Study in a Tertiary Hospital in Bogotá, Colombia

AU - Duarte, Angy Carolina Villamil

AU - Chavarro, Ernesto Fajardo

AU - Urbina, Adriana

AU - Becerra, Juan Fernando Cediel

AU - Borda, Sergio

AU - Falla, María Paula Cerón

AU - Ardila, María Andrea Calderón

AU - Bayona, Jorge Alberto Carrillo

PY - 2025/9

Y1 - 2025/9

N2 - Background and Objectives: Aortic aneurysms and dissections are life-threatening vascular disorders with high morbidity and mortality. Enhancing diagnostic and therapeutic strategies requires a precise characterization of their anatomical and clinical features. This study aimed to detail the demographic, clinical, and imaging-based anatomical characteristics of aortic aneurysms and dissections in a cohort of Colombian patients. Materials and Methods: We conducted a retrospective, descriptive, observational study at a tertiary hospital in Bogotá, Colombia. Adult patients (≥18 years) with radiologically confirmed aortic aneurysm or dissection on computed tomography angiography (CTA) between 2010 and 2021 were included. Demographic, clinical, and morphological data were extracted. Associations were explored using chi-squared and Mann–Whitney U tests. Multivariate logistic regression was applied to identify independent predictors of in-hospital mortality. Results: This study included 539 patients (mean age: 69.3 ± 11.5 years; 53.6% male). Infrarenal abdominal aortic aneurysms were the most frequent (63.7%), with fusiform morphology observed in 92% of cases. Saccular aneurysms were significantly more common in females (p = 0.0267) and in non-infrarenal segments (p = 0.0162). Among patients with aneurysms, aortic diameter was an independent predictor of mortality (OR = 1.03; 95% CI: 1.01–1.05; p < 0.001). No individual variable significantly predicted mortality in dissection cases. Conclusions: In this cohort, infrarenal location and fusiform shape predominate. Morphological patterns were associated with sex and anatomical distribution. Although trends were observed, no statistically significant predictors of death were identified in dissection cases. These findings highlight the value of early detection and tailored management and reinforce the importance of generating region-specific data to inform clinical decision making in Latin American settings.

AB - Background and Objectives: Aortic aneurysms and dissections are life-threatening vascular disorders with high morbidity and mortality. Enhancing diagnostic and therapeutic strategies requires a precise characterization of their anatomical and clinical features. This study aimed to detail the demographic, clinical, and imaging-based anatomical characteristics of aortic aneurysms and dissections in a cohort of Colombian patients. Materials and Methods: We conducted a retrospective, descriptive, observational study at a tertiary hospital in Bogotá, Colombia. Adult patients (≥18 years) with radiologically confirmed aortic aneurysm or dissection on computed tomography angiography (CTA) between 2010 and 2021 were included. Demographic, clinical, and morphological data were extracted. Associations were explored using chi-squared and Mann–Whitney U tests. Multivariate logistic regression was applied to identify independent predictors of in-hospital mortality. Results: This study included 539 patients (mean age: 69.3 ± 11.5 years; 53.6% male). Infrarenal abdominal aortic aneurysms were the most frequent (63.7%), with fusiform morphology observed in 92% of cases. Saccular aneurysms were significantly more common in females (p = 0.0267) and in non-infrarenal segments (p = 0.0162). Among patients with aneurysms, aortic diameter was an independent predictor of mortality (OR = 1.03; 95% CI: 1.01–1.05; p < 0.001). No individual variable significantly predicted mortality in dissection cases. Conclusions: In this cohort, infrarenal location and fusiform shape predominate. Morphological patterns were associated with sex and anatomical distribution. Although trends were observed, no statistically significant predictors of death were identified in dissection cases. These findings highlight the value of early detection and tailored management and reinforce the importance of generating region-specific data to inform clinical decision making in Latin American settings.

UR - https://www.scopus.com/pages/publications/105017416308

UR - https://www.scopus.com/pages/publications/105017416308#tab=citedBy

U2 - 10.3390/medicina61091558

DO - 10.3390/medicina61091558

M3 - Research Article

C2 - 41010949

SN - 1010-660X

VL - 61

JO - Medicina

JF - Medicina

IS - 9

M1 - 1558

ER -

Imaging-Based Anatomical Characterization of Aortic Aneurysms and Dissections: An Observational Study in a Tertiary Hospital in Bogotá, Colombia

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